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Published on: 7/14/2026

What could cause sharp pain in my left armpit that comes and goes?

Sharp, intermittent pain in the left armpit is often caused by nerve irritation, muscle strain, or swollen lymph nodes. In less common cases, a small mass or cyst pressing on nearby nerves can trigger sudden, temporary discomfort. Because the armpit contains nerves, blood vessels, and lymph tissue, even minor issues can cause sharp, come-and-go sensations.

Since symptoms overlap across many conditions—ranging from harmless muscle irritation to issues needing medical review—it's important to identify the likely cause before deciding on next steps. A quick, free, and confidential symptom check can help you narrow down possibilities in minutes, understand which specialist to see, and know whether your pain warrants urgent attention or at-home care. Taking a moment now can save you time, worry, and unnecessary appointments later.

Reviewed for medical accuracy: 07/14/2026

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Explanation

There are several reasons you might feel sharp pain in your armpit that comes and goes. One possibility is that a nerve in the upper chest or back is being irritated or pinched. Nerve irritation can send sudden, sharp signals that hurt for a short time. Sometimes, a condition called complex regional pain syndrome can occur when a small growth, like a lipoma (a fatty lump), presses on nerves. Even if you do not feel the lump, it might cause brief bursts of pain. Stretching or movement can also put pressure on sensitive areas in that region, leading to temporary sharp pain. Another possibility is that the pain is linked to a general nerve issue without a clear lump or injury. Most of the time, these conditions are not serious, but they can be annoying when they happen. If the pain continues or worsens, you can use a free symptom checker to help identify potential causes before talking to a healthcare provider who can make sure that there isn't an underlying problem that needs treatment.

(References)

  • Rubin DI, Shuster EA. Axillary pain as a heralding sign of neoplasm involving the upper thoracic root. Neurology. 2006 Jun 13;66(11):1760-2. doi: 10.1212/01.wnl.0000218165.93659.6c. PMID: 16769959.

  • Mikolajczyk AE, Zhang L, Zaman A. Atypical cause of axillary pain. _Am J Med_. 2016;129(2):e29-e30. doi:10.1016/j.amjmed.2015.09.039

  • Patel RH, Sheth R, Hus N. Complex Regional Pain Syndrome Caused by an Axillary Lipoma. Cureus. 2020 Dec 25;12(12):e12280. doi: 10.7759/cureus.12280. PMID: 33510987; PMCID: PMC7828746.

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