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Published on: 2/24/2026
Red, warm, swollen, painful skin on one leg is most often cellulitis, a bacterial infection that needs prompt medical evaluation and antibiotics, and you should seek urgent care if redness is rapidly spreading, you have fever or severe pain, or you notice red streaks, numbness, blisters, or blackened skin.
There are several factors to consider, including other possible causes like blood clots, venous disease, eczema, or gout and how quickly to act; see below for complete details on symptoms, risks, diagnosis, treatment, home care, prevention, and exact next steps.
If your leg is red, warm, swollen, and painful to the touch, it's natural to feel concerned. These symptoms are common, but they should never be ignored. One possible cause is cellulitis, a bacterial skin infection that can become serious without proper treatment.
Understanding what might be happening—and knowing what to do next—can help you act quickly and confidently.
Cellulitis is a bacterial infection of the deeper layers of the skin and the tissue underneath. It most often affects the lower legs, but it can occur anywhere on the body.
The infection typically develops when bacteria enter through:
Once inside, bacteria can spread rapidly through the skin tissue.
Cellulitis is not usually contagious, but it can become serious if left untreated.
Symptoms often develop quickly and may worsen over hours to a few days.
You may notice:
In some cases, red streaks may extend from the affected area. This can indicate the infection is spreading through the lymphatic system.
If redness is expanding quickly, or you develop fever, that's a sign you need prompt medical attention.
Swelling happens because your immune system is fighting infection. White blood cells rush to the area, causing inflammation. Fluid can also accumulate in the tissues.
With cellulitis, swelling is often:
Swelling without redness or pain may suggest a different cause, such as poor circulation or a blood clot. That's why medical evaluation is important—leg swelling has many possible causes.
Most cases of cellulitis respond well to antibiotics when treated early. However, without treatment, the infection can spread deeper into the body and cause complications such as:
Certain people are at higher risk of complications:
The key point: Cellulitis is treatable, but timing matters.
Call a doctor urgently or go to an emergency department if you notice:
These could be signs of a more serious infection.
Do not wait if symptoms are worsening.
A doctor usually diagnoses cellulitis by examining your skin and reviewing your symptoms. In most cases, no special tests are required.
However, your provider may order:
It's important to distinguish cellulitis from other conditions such as:
Because symptoms can overlap, professional evaluation is essential.
The primary treatment for cellulitis is antibiotics. Most mild cases are treated with oral antibiotics for 5–14 days.
Severe infections may require:
It's important to:
Improvement usually begins within 24–48 hours of starting antibiotics.
In addition to antibiotics, you can:
Avoid squeezing, massaging, or applying unapproved creams unless directed by a healthcare professional.
Yes. Recurrent cellulitis is common, especially in people with:
Preventive steps include:
If you've had cellulitis before, speak with your doctor about prevention strategies.
Not all red, swollen legs are caused by cellulitis. Other possibilities include:
Because these conditions require different treatments, guessing is not safe. Getting an accurate diagnosis protects your health.
If you're experiencing red, swollen skin and want to better understand your symptoms before seeing a doctor, consider using a free Cellulitis / Erysipelas symptom checker to evaluate whether your symptoms align with this bacterial infection.
A structured symptom check can help you:
This does not replace medical evaluation, but it can be a helpful starting point.
If you suspect cellulitis, don't wait several days to "see if it goes away."
Seek medical advice:
Early treatment prevents complications and often leads to faster recovery.
A red, swollen, painful leg is not something to ignore. Cellulitis is a common and treatable bacterial infection, but it can become serious if left untreated.
Key takeaways:
If you are experiencing symptoms that could be life threatening or serious, speak to a doctor immediately. Your health and safety come first.
Prompt evaluation, proper treatment, and simple preventive steps can make a significant difference—and most people recover fully with timely care.
(References)
* Delle Monache M, et al. The acute unilateral painful red swollen leg: diagnostic algorithm. Intern Emerg Med. 2019 Jun;14(4):659-668.
* O'Brien N, et al. Unilateral Leg Swelling: A Diagnostic Challenge. Am Fam Physician. 2020 Jan 1;101(1):31-38.
* Raff AB, Kroshinsky D. Cellulitis: A Review. JAMA. 2016 Oct 18;316(14):1478-1490.
* Di Minno MN, et al. D-dimer testing in patients with suspected deep vein thrombosis: a systematic review. J Thromb Haemost. 2021 Mar;19(3):772-785.
* Doughty A, et al. Clinical Assessment of Acute Leg Swelling. West J Emerg Med. 2018 Jan;19(1):154-164.
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