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Published on: 9/24/2026
Citalopram (brand name Celexa) is not a controlled substance in the United States, meaning it carries no DEA schedule classification because it is not considered to have abuse or addiction potential. It is, however, a prescription-only SSRI antidepressant, so it can only be obtained and adjusted under the direction of a licensed clinician. Even though it is not scheduled, citalopram should never be stopped abruptly, as discontinuation symptoms such as dizziness, irritability, flu-like feelings, and electric-shock sensations can occur, and it also carries dose limits tied to heart rhythm (QT prolongation) risks. There are several other important considerations, including drug interactions, mood or suicidality warnings, and state-level prescribing rules, so see below to understand more.
If you are weighing whether citalopram or another treatment fits your situation, or you are noticing new symptoms while taking it, getting clarity on what you are experiencing is the smartest first step. A free, instant, online symptom check can help you organize your symptoms, understand possible causes, and see which next steps or type of clinician to prioritize before your next appointment.
Last reviewed for medical accuracy: 09/24/2026
Is citalopram a controlled substance? Here’s what you need to know about citalopram’s legal status, how it works, and safe use.
What Is Citalopram?
Citalopram is a prescription medication in the class of selective serotonin reuptake inhibitors (SSRIs). It’s commonly used to treat:
SSRIs like citalopram increase serotonin levels in the brain, which can improve mood, reduce anxiety, and help you think more clearly.
A “controlled substance” is a drug regulated by law because of its potential for abuse or dependence. In the United States, the Drug Enforcement Administration (DEA) categorizes controlled substances into five schedules (I-V):
No—citalopram is not classified as a controlled substance by the DEA. It is:
Because it’s not scheduled, you won’t see citalopram on the DEA’s Schedules list. Your doctor can write a prescription that you fill at a pharmacy just like any other non-controlled medication.
SSRIs such as citalopram have:
These characteristics place citalopram outside DEA scheduling criteria.
Even though citalopram isn’t controlled, it’s still a prescription drug. Follow your healthcare provider’s directions:
Dosage and timing
Missed doses
Stopping treatment
Monitoring
Most people tolerate citalopram well, but be aware of:
If you ever feel life-threatening symptoms or severe side effects, seek medical attention without delay.
Before starting citalopram, share your full health history and medication list:
Feeling better on citalopram can take several weeks. To get the most benefit:
If you’re unsure whether your symptoms point to depression, anxiety, or another condition, consider a free, online symptom check, using the doctor approved Ubie Symptom Checker. It’s a quick way to gather insights and decide when to reach out for professional care.
Nothing in this guide replaces personalized medical advice. If you experience:
Speak to your doctor right away—or in an emergency, call 911. Always consult a healthcare professional before starting or stopping any medication.
(References)
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* Khan A, Schwartz K. Suicide risk and symptom reduction in patients assigned to placebo in duloxetine and escitalopram clinical trials: analysis of the FDA summary basis of approval reports. Ann Clin Psychiatry. 2007 Jan-Mar;19(1):31-6. doi: 10.1080/10401230601163550. PMID: 17453659.
* Zohar J. Escitalopram in the treatment of obsessive-compulsive disorder. Expert Rev Neurother. 2008 Mar;8(3):339-49. doi: 10.1586/14737175.8.3.339. PMID: 18345966.
* Aagaard L, Thirstrup S, Hansen EH. Opening the white boxes: the licensing documentation of efficacy and safety of psychotropic medicines for children. Pharmacoepidemiol Drug Saf. 2009 May;18(5):401-11. doi: 10.1002/pds.1735. PMID: 19326364.
* Sheeler RD, Ackerman MJ, Richelson E, Nelson TK, Staab JP, Tangalos EG, Dieser LM, Cunningham JL. Considerations on safety concerns about citalopram prescribing. Mayo Clin Proc. 2012 Nov;87(11):1042-5. doi: 10.1016/j.mayocp.2012.07.009. Epub 2012 Sep 24. PMID: 23018033; PMCID: PMC3532688.
* Keller DL. Prescribe escitalopram instead of citalopram. Am J Med. 2013 Jun;126(6):e21. doi: 10.1016/j.amjmed.2012.10.024. PMID: 23684405.
* Vieweg WV, Hasnain M, Howland RH. The reply. Am J Med. 2013 Jun;126(6):e23. doi: 10.1016/j.amjmed.2012.11.016. PMID: 23684406.
* Horton DB, Gerhard T, Davidow A, Strom BL. Impact of the black triangle label on prescribing of new drugs in the United Kingdom: lessons for the United States at a time of deregulation. Pharmacoepidemiol Drug Saf. 2017 Nov;26(11):1307-1313. doi: 10.1002/pds.4304. Epub 2017 Aug 31. PMID: 28857309; PMCID: PMC5670006.
* Hooimeyer A, Bhasale A, Perry L, Fabbri A, Mohammad A, McEwin E, Mintzes B. Regulatory post-market drug safety advisories on cardiac harm: A comparison of four national regulatory agencies. Pharmacol Res Perspect. 2020 Dec;8(6):e00680. doi: 10.1002/prp2.680. PMID: 33169534; PMCID: PMC7652786.
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