What are the side effects of citalopram?

Side Effects of Citalopram: What You Need to Know

Citalopram is a selective serotonin reuptake inhibitor (SSRI) commonly prescribed for depression and anxiety. You may come across the term “citalopram controlled substance,” but unlike medications in schedules I–V, citalopram is not classified as a controlled substance by the U.S. Drug Enforcement Administration. It is, however, prescription-only—meaning your doctor will assess if it’s right for you before writing a prescription.

Understanding potential side effects can help you recognize what’s normal, what may improve over time, and what requires medical attention. This guide draws on credible sources and uses clear language; it’s not meant to create anxiety, but rather to inform. Always speak to a healthcare professional about any concerns.

How Citalopram Works

Citalopram increases serotonin levels in the brain, which can improve mood, reduce anxiety, and help relieve physical symptoms of stress. Because every person’s body reacts differently, side effects vary in type and severity.

Common Side Effects

Most people tolerate citalopram well, especially after the first few weeks. Common side effects often fade as your body adjusts:

• Nausea
  Mild queasiness, usually in the first 1–2 weeks.
• Headache
  Tension-type or mild migraine-like headaches.
• Dry Mouth
  Sipping water, sugar-free gum or lozenges can help.
• Drowsiness or Insomnia
  You may feel sleepy or have trouble sleeping; adjusting dose timing can help.
• Sweating
  Increased perspiration, particularly at night.
• Fatigue
  Tiredness that usually improves after 1–2 weeks.
• Sexual Side Effects
  Reduced libido, delayed ejaculation or difficulty with orgasm.
• Diarrhea or Constipation
  Mild digestive upset as your gut adjusts.

If these effects interfere with daily life or worsen after a month, talk to your prescriber about dose adjustments or timing changes.

Less Common Side Effects

These occur in fewer than 10% of users but are still worth noting:

• Tremor (shakiness in hands)
• Appetite Changes (weight loss or gain)
• Yawning (especially when starting or increasing dose)
• Blurred Vision
• Anxiety or Nervousness (paradoxical increase)
• Restless Legs (uncomfortable urge to move legs)
• Yawning
• Mild Skin Rash or Itching

If you notice any new or bothersome symptoms, report them. Sometimes switching to another SSRI or adjusting your regimen helps.

Rare but Serious Side Effects

Though uncommon, these warrant immediate medical attention:

• Serotonin Syndrome
  Occurs when serotonin levels get too high. Symptoms may include high fever, rapid heartbeat, agitation, tremors, and confusion. This is a medical emergency—call 911 or go to the nearest emergency department.
• Severe Allergic Reaction (Anaphylaxis)
  Signs: hives, swelling of face or throat, difficulty breathing. Seek emergency care right away.
• QT Interval Prolongation
  Citalopram can rarely affect heart rhythm, leading to palpitations, dizziness, or fainting. Notify your doctor immediately if you experience these.
• Low Sodium (Hyponatremia)
  More common in older adults. Look for headache, confusion, weakness, seizures.
• Severe Mood Changes or Suicidal Thoughts
  Pay close attention to new or worsening depression, anxiety, or thoughts of self-harm—especially in the first few months. This risk is higher in young adults under 25.

Managing Side Effects

Many side effects improve with time; here are strategies that may help:

• Start with a low dose and increase gradually under your doctor’s guidance.
• Take citalopram in the morning if it causes insomnia, or in the evening if it causes drowsiness.
• Stay hydrated and keep healthy snacks on hand to counteract nausea.
• Maintain a regular sleep schedule and practice relaxation techniques for insomnia.
• Use lubricants or discuss alternative therapies with your doctor for sexual side effects.
• Monitor your weight and appetite; consider light exercise to manage changes.
• Keep a symptom diary to track side effects, their onset, and any patterns.

When to Reach Out for Help

If you’re uncertain about a symptom or it feels serious, don’t hesitate:

• Sudden chest pain, irregular heartbeat, or fainting
• High fever, severe headache, stiff neck, or sensitivity to light
• Signs of infection (fever with rash, sore throat)
• New or worsening depression, unusual mood swings, suicidal thoughts
• Severe gastrointestinal distress or dehydration

For a free, online symptom check, using the doctor approved Ubie Symptom Checker, visit this link.

Discussing Citalopram with Your Doctor

Before starting or stopping citalopram, tell your healthcare provider about:

• Current medications (including over-the-counter drugs, supplements)
• Personal or family history of heart issues, seizures, glaucoma, or bipolar disorder
• Pregnancy status or plans to become pregnant
• Breastfeeding concerns

Never adjust your dose or discontinue suddenly; suddenly stopping citalopram can cause withdrawal symptoms such as dizziness, irritability, and insomnia.

Key Takeaways

• Citalopram is an SSRI—not a “controlled substance” under DEA schedules—but it requires a prescription.
• Common side effects (nausea, headache, fatigue) often improve within weeks.
• Less common or rare side effects should be reported promptly.
• Serious reactions (serotonin syndrome, allergic reaction, severe mood changes) require immediate medical attention.
• Effective management includes dose timing, hydration, sleep hygiene, and open communication with your doctor.
• Use the Ubie Symptom Checker for a free, online assessment.

Always speak to a doctor about any side effect that is severe, persistent, or life-threatening. Your healthcare team is there to ensure you get the benefits of citalopram while minimizing risks.