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Published on: 2/24/2026
Confusion and nausea can be signs of low sodium in the blood, or hyponatremia, which can progress from mild to life-threatening and warrants prompt medical care, especially with severe headache, persistent vomiting, seizures, or extreme drowsiness.
There are several factors to consider, from excess water intake and medications to heart, kidney, liver, thyroid, or adrenal problems, and treatment depends on the cause with sodium corrected slowly to avoid harm. See complete details below to learn key risks, when it is an emergency, what tests confirm it, and the right next steps.
If you're feeling confused, nauseated, unusually tired, or just "not yourself," low sodium levels in your blood—called hyponatremia—could be a possible cause.
Hyponatremia is a common but sometimes serious medical condition. It happens when the level of sodium in your blood falls below normal. Sodium is an essential electrolyte that helps regulate:
When sodium levels drop too low, your body—especially your brain—can't function properly. Understanding why this happens and what to do next can help you stay safe and get appropriate care.
Hyponatremia occurs when blood sodium levels fall below 135 mEq/L. It can range from mild to severe:
The more rapidly sodium levels fall, the more dangerous the situation can be. A slow decline may cause subtle symptoms. A sudden drop can become life-threatening.
Sodium plays a key role in balancing fluids inside and outside your cells. When sodium levels fall:
Because your skull limits space, brain swelling can lead to symptoms such as:
In more severe cases, hyponatremia can cause:
This is why confusion combined with nausea should never be ignored—especially in older adults.
Hyponatremia usually develops because of an imbalance between water and sodium—not simply from "not eating enough salt."
Here are the most common causes:
Excessive water intake can dilute sodium levels. This sometimes occurs in:
Certain medications increase the risk of hyponatremia, including:
Older adults are especially vulnerable.
Problems with hormone regulation can affect sodium balance:
Chronic medical conditions can disrupt fluid regulation and cause dilutional hyponatremia.
Prolonged gastrointestinal illness can lead to sodium loss and dehydration.
Hospitalized patients are at higher risk due to IV fluids, medications, or stress-related hormone changes.
Certain groups are more likely to develop hyponatremia:
If you fall into one of these categories and develop confusion or nausea, medical evaluation is especially important.
Mild hyponatremia may cause only subtle symptoms. However, severe or rapidly developing hyponatremia is a medical emergency.
Seek immediate medical care if someone experiences:
Do not wait to "see if it gets better." Rapid sodium shifts can be life-threatening.
Diagnosis is straightforward with a blood test measuring sodium levels. However, identifying the cause requires additional evaluation.
Your doctor may order:
Because treatment depends entirely on the underlying cause, accurate diagnosis is critical.
Treatment varies depending on:
If symptoms are minimal, treatment may include:
Doctors may:
Severe hyponatremia requires hospital care. Treatment may include:
It's important to note: Sodium must be corrected slowly. Raising levels too quickly can cause a serious neurological condition called osmotic demyelination syndrome. That's why medical supervision is essential.
You should not attempt to self-treat hyponatremia with salt tablets or sports drinks without medical guidance.
While mild cases may only require fluid adjustments, the wrong approach can make the problem worse—especially if the cause involves fluid retention rather than sodium loss.
If you're experiencing symptoms like confusion, nausea, or unexplained fatigue and want to understand whether Hyponatremia could be the cause, a quick assessment may help you determine if you need to seek medical care right away.
However, an online tool is not a substitute for professional evaluation.
Prevention depends on managing underlying risks.
General tips include:
Older adults should be especially cautious, as symptoms may be mistaken for normal aging or dementia.
Confusion is never "normal." Even mild disorientation can signal a serious imbalance like hyponatremia.
In older adults, hyponatremia may present as:
Because these symptoms overlap with other conditions, blood testing is often needed to identify the cause.
Hyponatremia is a potentially serious condition caused by low sodium levels in the blood. It can lead to confusion, nausea, headache, and in severe cases, seizures or coma.
The key points to remember:
If you are experiencing confusion, vomiting, severe headache, seizures, or extreme drowsiness, seek emergency medical attention immediately.
Even if symptoms seem mild, it's wise to speak to a doctor about persistent nausea, mental changes, or unusual fatigue—especially if you have risk factors for hyponatremia.
Low sodium is treatable. The most important step is recognizing the symptoms early and getting appropriate medical care.
(References)
* Verbalis, J. G., Goldsmith, S. R., Greenberg, A., Schrier, R. W., & Sterns, R. H. (2021). The diagnosis, evaluation, and treatment of hyponatremia. New England Journal of Medicine, 385(13), 1215-1226.
* Clayton, J. A., Rodgers, C., & McCammack, L. (2020). Hyponatremia: A Practical Approach to Diagnosis and Treatment. American Family Physician, 101(12), 741-748.
* Palmer, B. F., & Sterns, R. H. (2019). Clinical approaches to the treatment of hyponatremia. Kidney International, 95(4), 762-773.
* Hoorn, E. J., & Zietse, R. (2017). Diagnosis and Treatment of Hyponatremia: Core Curriculum 2017. American Journal of Kidney Diseases, 69(4), 543-552.
* Spasovski, G., Vanholder, R., Allolio, B., Annane, D., Ball, S., Bichet, D., ... & European Society of Endocrinology and European Society of Intensive Care Medicine. (2014). Clinical practice guideline on diagnosis and treatment of hyponatraemia. Intensive Care Medicine, 40, 320-331.
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