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Published on: 1/29/2026
Crohn’s pain often moves because inflammation can involve different parts of the bowel at different times, intestinal motility and gas shift discomfort along the tract, and shared nerve pathways create referred pain; scar-related narrowing and stress can also make pain feel migratory. There are several factors to consider. See below to understand more, including red flags that need urgent care and practical next steps like symptom tracking and when to talk with your doctor.
Crohn's disease is a chronic inflammatory condition that can affect any part of the digestive tract. One of the most confusing—and often frustrating—symptoms people report is abdominal pain that seems to move around. One day it may be low on the right side, another day higher up, or spread across the belly. This shifting pain is real, common in Crohn's, and has clear medical reasons behind it.
Below is a clear, medically grounded explanation of why Crohn's pain moves around the abdomen, written in plain language and based on well-established gastrointestinal research and clinical practice.
To understand why Crohn's pain moves, it helps to know how Crohn's behaves in the body.
Crohn's is a type of inflammatory bowel disease (IBD). Unlike some other conditions, it can affect any part of the gastrointestinal (GI) tract, from the mouth to the anus. However, it most commonly involves:
Inflammation in Crohn's is also patchy, meaning it affects some areas while skipping others. Doctors often call this "skip lesions."
Because different parts of the digestive tract sit in different areas of the abdomen, pain can appear to "travel" as inflammation changes location or intensity.
One of the main reasons Crohn's pain moves is that the disease itself is not fixed in one spot.
Inflammation may:
Each section of the gut sends pain signals to different nerve pathways, which the brain interprets as pain in different locations.
For example:
As inflammation shifts or expands, the location of pain can shift with it.
Your intestines are in constant motion, pushing food forward through rhythmic muscle contractions called peristalsis.
In Crohn's:
This can cause:
So even if inflammation stays in one place, the sensation of pain can travel as the gut contracts and relaxes.
Abdominal organs share nerve networks. Because of this, the brain doesn't always pinpoint pain accurately.
This leads to referred pain, where discomfort is felt in a nearby—or even distant—area from the actual source.
In Crohn's:
This neurological overlap explains why Crohn's pain may feel unpredictable or hard to locate.
Crohn's is known for cycles of:
During flares:
As inflammation improves:
This changing inflammatory pattern can make pain feel inconsistent, even over short periods.
Over time, repeated inflammation can lead to scar tissue (fibrosis) in the bowel wall. This can narrow parts of the intestine.
When this happens:
Because digestion is continuous, the pressure point—and therefore the pain—can move.
People with Crohn's often experience:
Even normal amounts of gas can cause discomfort in inflamed or sensitive bowel tissue. As gas moves, the pain can move with it.
This is one reason pain may:
Stress does not cause Crohn's, but it can amplify symptoms.
The gut and brain are closely connected through the nervous system. Stress can:
This can make Crohn's pain feel more diffuse or harder to pinpoint during stressful periods.
While shifting abdominal pain is common in Crohn's, some symptoms should never be ignored.
Speak to a doctor urgently if pain is accompanied by:
These could signal complications that need immediate medical care.
Because Crohn's pain can be complex, tracking symptoms is helpful. If you're experiencing unexplained or shifting abdominal pain and want to better understand if it could be related to Crohn's Disease, a free AI-powered symptom checker can help you organize your symptoms and prepare meaningful questions before your next doctor's visit.
This is not a diagnosis, but it can help guide more informed conversations.
Crohn's is a lifelong condition that benefits from ongoing medical care. A doctor can:
If symptoms change, worsen, or interfere with daily life, speak to a doctor, especially about anything that could be serious or life-threatening.
Crohn's pain moves around the abdomen because:
This pattern is common, medically understood, and manageable with proper care. While Crohn's is not something to ignore, understanding why symptoms behave the way they do can make them feel less frightening and more predictable.
With the right support and medical guidance, many people with Crohn's find ways to reduce pain and regain control over their daily lives.
(References)
* Keszthelyi D, Troost FJ, Masclee AA. Mechanisms of abdominal pain in inflammatory bowel disease. Br J Pharmacol. 2017 Oct;174(18):3902-3916. doi: 10.1111/bph.13945. Epub 2017 Oct 1. PMID: 28833139; PMCID: PMC5596486.
* Lackner JM, Drossman DA. Pain in Inflammatory Bowel Disease: A Review of Pathophysiology, Assessment, and Treatment. Dig Dis Sci. 2022 Jan 10. doi: 10.1007/s10620-021-07340-9. Epub ahead of print. PMID: 35006323.
* Ohman L, Söderholm JD. Visceral hypersensitivity in inflammatory bowel disease: a clinical and neurobiological perspective. Neurogastroenterol Motil. 2017 Apr;29(4). doi: 10.1111/nmo.13012. Epub 2017 Jan 26. PMID: 28124976.
* Sridharan N, Khan FJ, D'Silva K, Singh B, Kothari M, Patel R. Neuropathic pain in inflammatory bowel disease: a narrative review. Ann Gastroenterol. 2023 Mar-Apr;36(2):107-113. doi: 10.20524/aog.2022.0768. Epub 2022 Dec 27. PMID: 37007786; PMCID: PMC10058863.
* Corsetti M, Bravi I, Barrese V, Cicala M. Motility disturbances and visceral hypersensitivity in inflammatory bowel disease. J Clin Med. 2022 Apr 19;11(8):2253. doi: 10.3390/jcm11082253. PMID: 35456488; PMCID: PMC9028889.
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