Our Services
Medical Information
Helpful Resources
Published on: 8/20/2026
Yes, marijuana can cause feelings of detachment or numbness, a state known as depersonalization. This happens because THC alters brain activity in areas that regulate self-awareness, emotion, and perception, sometimes leaving users feeling disconnected from themselves, their body, or their surroundings.
These symptoms can be temporary, but for some people they linger or return even after the high fades. Since detachment and numbness can also signal anxiety, depression, or other underlying conditions, it's important not to guess. Take a free, instant, online symptom check to better understand what may be causing these feelings and get clear guidance on your next steps.
Reviewed for medical accuracy: 07/15/2026
Quick answers
The most common questions people search after this page
When you smoke or use marijuana, it can change blood flow and how your brain processes things. For some people, this results in feeling like you're not fully connected to yourself. You might feel as if you are watching yourself from outside or that everything feels unreal. This sensation is known as depersonalization.
Not everyone has these experiences, but it can happen, especially in people who are more sensitive to marijuana's effects or who use it in higher quantities. These feelings usually pass as the effects of the marijuana wear off.
However, if you often feel detached or disconnected after using weed, or if it makes you really upset, it might be a good idea to talk with a trusted adult or healthcare professional. If you're experiencing concerning symptoms and want to better understand what might be going on, you can check your symptoms with a free AI-powered assessment to help guide your next steps. Remember, taking care of your mental health is just as important as taking care of your physical health, and there are lots of people who can help you if these feelings become too strong.
(References)
Mathew RJ, Wilson WH, Tant SR. Acute changes in cerebral blood flow associated with marijuana smoking. Acta Psychiatr Scand. 1989 Feb;79(2):118-28. doi: 10.1111/j.1600-0447.1989.tb08579.x. PMID: 2923005.
Mathew RJ, Wilson WH, Humphreys D, Lowe JV, Weithe KE. Depersonalization after marijuana smoking. Biol Psychiatry. 1993 Mar 15;33(6):431-41. doi: 10.1016/0006-3223(93)90171-9. PMID: 8490070.
Hürlimann F, Kupferschmid S, Simon AE. Cannabis-induced depersonalization disorder in adolescence. Neuropsychobiology. 2012;65(3):141-6. doi: 10.1159/000334605. Epub 2012 Feb 25. PMID: 22378193.
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.