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Published on: 4/28/2026
Skin tags are more than a cosmetic nuisance; research shows that chronic high insulin levels in insulin resistance can drive skin cell proliferation and tiny blood vessel growth leading to skin tags. Common risk factors such as excess abdominal weight, physical inactivity, and a diet high in refined sugars contribute to both insulin resistance and new skin tag development.
There are several factors to consider; see below for more important details that could affect your next healthcare steps.
Skin tags are common, soft, benign growths often dismissed as purely cosmetic. However, emerging evidence shows a strong connection between insulin resistance—a precursor to type 2 diabetes—and the development of skin tags. Understanding this link can help you take charge of your metabolic health, recognize potential warning signs, and seek timely medical advice.
Skin tags (acrochordons) are:
While most people view skin tags as a cosmetic nuisance, their sudden appearance or increase in number can hint at underlying metabolic issues.
Insulin is a hormone produced by the pancreas that helps cells absorb glucose (sugar) from the bloodstream for energy. Insulin resistance occurs when:
Over time, this can lead to prediabetes and eventually type 2 diabetes. Common contributors to insulin resistance include:
Recognizing early signs of insulin resistance can be crucial for preventing diabetes and its complications.
Research suggests that elevated insulin levels may stimulate the growth of skin tags by affecting cell proliferation and blood vessel formation in the skin. Here's how:
Key studies have found that people with multiple skin tags often have higher fasting insulin levels compared to those without skin tags. While not everyone with skin tags has insulin resistance, a significant number do.
If you're seeing more skin tags than usual, consider these associated risk factors for insulin resistance:
Being aware of these risk factors can help you make lifestyle adjustments and prompt you to discuss screening tests with your doctor.
You can reduce the likelihood of developing insulin resistance—and potentially limit new skin tags—by adopting healthy habits:
Making these changes can have a broad impact on your metabolic health, beyond just reducing skin tags.
While skin tags themselves are harmless, you may choose to have them removed for comfort or cosmetic reasons. Removal methods include:
Always have skin tag removal performed by a qualified healthcare professional to minimize infection risk and scarring. Attempting home removals with over-the-counter tools is not recommended.
Although skin tags are benign, consult a healthcare professional if you experience any of the following:
Any of these could indicate a more serious condition or complication of diabetes. If you suspect you have insulin resistance or diabetes, talk to your doctor about appropriate screening tests.
Because prolonged high blood sugar can lead to nerve damage over time, it's also important to monitor for related complications. You can take a free symptom assessment for Diabetic Neuropathy to help identify early warning signs of nerve-related issues that may accompany insulin resistance and diabetes.
Detecting insulin resistance early allows you to:
Regular check-ups, blood tests, and honest discussions with your doctor are key to staying ahead of metabolic health challenges.
By understanding the connection between insulin resistance and skin tags, you empower yourself to make informed health decisions, reduce future risks, and seek appropriate medical care when needed. If you have concerns about skin tags, blood sugar, or any unusual symptoms, please speak to a doctor as soon as possible.
(References)
* Zohora F, Hassan M, Akter R, Kabir MA. Acrochordons as a cutaneous sign of insulin resistance: a meta-analysis. Int J Dermatol. 2023 Dec;62(12):1500-1507. doi: 10.1111/ijd.16723. Epub 2023 Sep 6. PMID: 37672236.
* Gholamhoseinian A, Khadivian S, Bagheri L, Gholamhoseinian A. Association between acrochordons and insulin resistance and metabolic syndrome: A systematic review and meta-analysis. J Cosmet Dermatol. 2020 Jan;19(1):15-21. doi: 10.1111/jocd.13063. Epub 2019 Jul 23. PMID: 31336495.
* AlGhamdi H, Kasi D, Almulla S, Alkhaja J, Alsaeed M, Alotaibi A, Alali A. Cutaneous Manifestations of Insulin Resistance: A Narrative Review. Cureus. 2023 Jun 20;15(6):e40702. doi: 10.7759/cureus.40702. PMID: 37497148; PMCID: PMC10357283.
* Singh M, Gupta A, Agrawal A. Acrochordons as a sign of metabolic syndrome: A cross-sectional study. J Clin Aesthet Dermatol. 2022 Jul;15(7):E54-E58. Epub 2022 Jul 1. PMID: 35921649; PMCID: PMC9340576.
* Agrawal R, Sinha P, Dhali TK, Kumar A. Acrochordon: a cutaneous marker of insulin resistance and dyslipidemia. Indian J Dermatol. 2017 Mar-Apr;62(2):207-209. doi: 10.4103/0019-5154.203704. PMID: 28640078; PMCID: PMC5448375.
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