Published on: 5/6/2025
Gynecomastia, or enlarged male breasts, often happens when the balance between estrogen and testosterone is upset. When there is low testosterone or high estrogen for any reason, it can lead to extra breast tissue growth.
Gynecomastia is the term used when a man’s breast tissue grows larger than usual. This happens because of an imbalance of hormones in the body. In healthy males, testosterone is higher and helps keep estrogen (a hormone also found in men) in check. When testosterone levels drop or estrogen levels rise, the balance shifts. Low testosterone means there isn’t enough of the hormone that usually helps prevent the growth of breast tissue. With less testosterone to control it, estrogen’s effects become stronger, which can lead to the development of extra breast tissue. Other factors, like puberty, aging, use of certain medications, or other health issues, can also upset this balance. In some cases, the body may produce more estrogen or become more sensitive to it. Checking hormone levels can help understand the cause. Treatment may involve addressing the underlying cause, adjusting medications, or using therapies that target the hormonal imbalance.
(References)
Shi Z, Xin M. Endocrine Hormones and Their Impact on Pubertal Gynecomastia. J Clin Med. 2024 Dec 30;14(1):158. doi: 10.3390/jcm14010158. PMID: 39797240; PMCID: PMC11721017.
Sansone A, Romanelli F, Sansone M, Lenzi A, Di Luigi L. Gynecomastia and hormones. Endocrine. 2017 Jan;55(1):37-44. doi: 10.1007/s12020-016-0975-9. Epub 2016 May 4. PMID: 27145756.
Lemaine V, Cayci C, Simmons PS, Petty P. Gynecomastia in adolescent males. Semin Plast Surg. 2013 Feb;27(1):56-61. doi: 10.1055/s-0033-1347166. PMID: 24872741; PMCID: PMC3706045.
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