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Published on: 10/30/2025

What factors shorten life expectancy in lupus patients?

Lupus patients may have a shorter life expectancy due to complications like kidney disease, infections, and heart problems. See below to understand more.

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Explanation

Lupus is an autoimmune disease that can affect many parts of the body, leading to various health issues that may reduce life expectancy.

Factors that can shorten life expectancy include:

  1. Kidney Disease: Lupus can cause kidney inflammation, known as lupus nephritis, which can lead to kidney failure and is a significant cause of mortality.

  2. Infections: Patients with lupus are at higher risk for infections due to both the disease and the immunosuppressive treatments used to manage it.

  3. Heart Problems: Lupus can increase the risk of cardiovascular diseases, such as heart attacks and strokes, due to inflammation and other factors.

  4. Late-Onset Lupus: People who develop lupus later in life may face different challenges and complications that can affect their survival.

  5. Disease Severity and Flare-ups: More severe disease and frequent flare-ups can lead to more complications and a higher risk of mortality.

Managing lupus effectively with regular medical care and monitoring can help mitigate these risks and improve life expectancy.

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