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Published on: 1/31/2026
Farxiga (dapagliflozin) in older adults: key benefits and risks
Farxiga can meaningfully help older adults by improving blood sugar with low hypoglycemia risk, reducing heart failure hospitalizations, and slowing chronic kidney disease progression. However, it may also increase risks of dehydration, urinary tract infections (UTIs), and dizziness from lower blood pressure.
Key safety tips for older adults on Farxiga:
Because symptoms like dizziness, fatigue, urinary changes, or dehydration can overlap with other conditions, it's important to understand what's really going on before deciding your next step. Taking a free, instant, online symptom check can help you quickly identify possible causes, spot red flags, and know when to call your doctor—empowering you to make informed decisions about your care.
Reviewed for medical accuracy: 07/09/2026
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Submit your own QuestionIf you are over 65 and have been prescribed farxiga (dapagliflozin), it's normal to want a clear, balanced explanation of what it can help with—and what to watch for. Farxiga is widely used and well-studied, including in older adults, but age can change how your body responds to medications. Below is a practical, plain‑language guide to the benefits and risks of farxiga, with special attention to dehydration, urinary tract infections (UTIs), and dizziness.
Farxiga is a prescription medication in a class called SGLT2 inhibitors. It works by helping your kidneys remove excess sugar through the urine.
Doctors prescribe farxiga for several conditions, including:
Because these conditions are more common after age 65, farxiga is frequently used in older adults.
Large clinical studies and real‑world use show that farxiga offers meaningful benefits, even later in life.
Farxiga lowers blood sugar without relying on insulin.
Why this matters for older adults:
Farxiga reduces the risk of hospitalization for heart failure and can improve symptoms like shortness of breath and fatigue.
Key advantages:
Farxiga slows the progression of chronic kidney disease.
For those over 65:
Farxiga may cause mild weight loss and slightly lower blood pressure.
While farxiga has real benefits, certain side effects deserve extra attention after age 65.
Farxiga makes you urinate more to remove sugar from the body. This can also cause fluid loss.
Older adults are more vulnerable because:
If you're experiencing these symptoms and want to better understand whether Dehydration may be the cause, a free AI-powered symptom checker can help you evaluate your condition and decide if you should seek medical attention.
Because farxiga increases sugar in the urine, it can create an environment where bacteria grow more easily.
Older adults may already be at higher risk due to:
Most UTIs linked to farxiga are mild and treatable, especially when caught early.
Farxiga can lower blood pressure slightly. In older adults, this may cause:
This is more likely if you:
Falls are not an inevitable part of aging, and medication adjustments can often reduce this risk.
Less common but important side effects include:
Your healthcare provider will typically monitor kidney function and overall health through regular blood tests.
You may need closer monitoring or a different treatment if you:
This does not mean farxiga is unsafe—but it does mean personalized care is essential.
Before starting or continuing farxiga, consider discussing:
Always speak to a doctor right away if you experience symptoms that feel severe, sudden, or life‑threatening, such as fainting, confusion, high fever, or signs of a serious infection.
Farxiga offers real, evidence‑based benefits for blood sugar control, heart failure, and kidney protection—even in older adults. For many people over 65, these benefits outweigh the risks when the medication is used thoughtfully and monitored closely.
At the same time, dehydration, UTIs, and dizziness are not side effects to ignore. The good news is that most risks can be reduced with:
If something doesn't feel right, trust your instincts and speak to a doctor. Medications work best when they fit your body, your health goals, and your stage of life.
With the right guidance, farxiga can be a helpful part of staying healthier and more independent as you age.
(References)
* Li D, Li H, Li S, Lin H, Jia W, Wang Z, Gu R. Dapagliflozin in elderly patients with type 2 diabetes: a systematic review and meta-analysis. J Diabetes Complications. 2019 May;33(5):372-381. doi: 10.1016/j.jdiacomp.2019.01.011. Epub 2019 Jan 21. PMID: 30678683.
* Alatawi Y, Alnami F, Alenzi F, Alenzi A, Alsogair M. Safety of SGLT2 Inhibitors in Older Patients with Type 2 Diabetes Mellitus: A Narrative Review. Cureus. 2022 Oct 11;14(10):e30198. doi: 10.7759/cureus.30198. PMID: 36364132; PMCID: PMC9642699.
* Tella SH, Chung S, Gupte R, Vella A, Zaccardi F. Adverse events of SGLT2 inhibitors in older adults with type 2 diabetes: A systematic review and meta-analysis. Diabetes Obes Metab. 2020 Aug;22(8):1292-1304. doi: 10.1111/dom.14039. Epub 2020 May 19. PMID: 32415664.
* Cho NH, Vella A, Cho YK, Pan C, Han P, Li Y, Rhee EJ, Tan H, Yang W. Real-world effectiveness and safety of dapagliflozin in older patients with type 2 diabetes mellitus from the Asia-Pacific region: Results from the Asia-Pacific Diabetes and Cardiovascular (ADVICE) Registry. J Diabetes Investig. 2021 Jul;12(7):1233-1243. doi: 10.1111/jdi.13508. Epub 2021 Mar 22. PMID: 33918076; PMCID: PMC8255953.
* Mascolo A, Sessa M, Faillace P, Vitale C, Capuano A. Cardiorenal Benefits of SGLT2 Inhibitors in the Elderly: A Narrative Review. J Cardiovasc Dev Dis. 2022 May 19;9(5):165. doi: 10.3390/jcdd9050165. PMID: 35626998; PMCID: PMC9144490.
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