Over 65 Starting Farxiga? What to Watch in the First 2 Weeks

Over 65 and Starting Farxiga? What to Watch in the First 2 Weeks

Starting a new medication can feel overwhelming—especially after age 65, when the body may respond differently than it did years ago. Farxiga (dapagliflozin) is a well-studied prescription medicine used for type 2 diabetes, heart failure, and chronic kidney disease. Many adults over 65 take Farxiga safely and benefit from it, but the first two weeks are an important adjustment period.

Below is a clear, practical guide to what to expect, what to watch for, and when to speak to a doctor—based on established clinical knowledge and prescribing guidance.

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What Is Farxiga and Why Is It Prescribed?

Farxiga belongs to a class of medications called SGLT2 inhibitors. It works by helping the kidneys remove extra glucose (sugar) from the blood through urine. This action can:

• Lower blood sugar in type 2 diabetes
• Reduce hospitalizations for heart failure
• Slow the progression of chronic kidney disease

Because Farxiga works through the kidneys, age-related changes in kidney function are especially relevant for adults over 65.

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Why the First 2 Weeks Matter

The first two weeks on Farxiga are when your body adjusts to:

• Increased urination
• Changes in fluid balance
• Lower blood sugar levels

Most side effects—if they occur—show up early and are often mild. Knowing what’s normal versus what needs medical attention can help you stay safe and confident.

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Common Changes You May Notice (Often Mild)

These effects are common and usually improve as your body adjusts:

1. More Frequent Urination

Farxiga helps remove sugar through urine, which naturally increases how often you need to go.

• You may notice more bathroom trips, especially at night
• This is expected and not dangerous on its own

Tip: Stay well hydrated unless your doctor has advised fluid restrictions.

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2. Mild Dehydration or Thirst

Because Farxiga causes fluid loss, some people feel:

• Thirsty
• A dry mouth
• Slight fatigue

What helps:

• Sip water regularly throughout the day
• Avoid excessive caffeine or alcohol, which can worsen dehydration

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3. Lower Blood Sugar (Especially If Combined With Other Medications)

Farxiga alone has a low risk of causing dangerously low blood sugar. However, the risk increases if you also take insulin or certain other diabetes medications.

Watch for:

• Shakiness
• Sweating
• Dizziness
• Confusion

If this happens, check your blood sugar if you can and speak to a doctor promptly.

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Side Effects to Watch More Closely in Adults Over 65

Some side effects are uncommon but more important to recognize early.

4. Dizziness or Lightheadedness

This can happen due to changes in blood pressure or fluid balance.

• More likely when standing up quickly
• More common in the first week

What to do:

• Stand up slowly
• Sit or lie down if you feel unsteady
• Tell your doctor if it persists

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5. Genital Yeast Infections

Because Farxiga increases sugar in the urine, it can raise the risk of yeast infections—especially in the first few weeks.

Possible symptoms include:

• Itching or burning
• Redness or irritation
• Unusual discharge

These infections are usually treatable and not dangerous, but they should not be ignored. If you notice symptoms, you might consider doing a free, online symptom check for Candidal Vulvovaginitis (Yeast Infection) to help you understand what may be going on before you speak to a doctor.

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6. Urinary Tract Infections (UTIs)

UTIs are slightly more common with Farxiga.

Watch for:

• Burning with urination
• Urgent need to urinate
• Cloudy or strong-smelling urine
• Fever or back pain (more serious)

Older adults should contact a doctor early, as UTIs can worsen quickly if untreated.

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Rare but Serious Symptoms: When to Act Fast

These effects are uncommon, but it’s important not to ignore them.

7. Signs of Severe Dehydration or Kidney Stress

Call your doctor right away if you notice:

• Very low urine output
• Severe weakness
• Confusion
• Fainting

These symptoms are more likely if you are also taking diuretics (“water pills”) or become ill with vomiting or diarrhea.

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8. Symptoms of Diabetic Ketoacidosis (DKA)

Although rare, Farxiga has been linked to a condition called euglycemic DKA, even when blood sugar isn’t very high.

Seek immediate medical care if you have:

• Nausea or vomiting
• Abdominal pain
• Deep or rapid breathing
• Fruity-smelling breath

This is a medical emergency—do not wait.

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Practical Tips for the First 2 Weeks on Farxiga

To support a smooth start:

• Take Farxiga at the same time each day, usually in the morning
• Monitor blood sugar as recommended
• Drink fluids regularly, unless your doctor limits fluids
• Weigh yourself daily if advised (sudden weight loss may signal fluid loss)
• Pause and call your doctor if you become sick with vomiting or diarrhea

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Medication Interactions to Review

Before or soon after starting Farxiga, make sure your doctor knows if you take:

• Diuretics (water pills)
• Insulin or sulfonylureas
• Blood pressure medications
• NSAIDs taken frequently

This helps reduce the risk of low blood pressure, dehydration, or kidney stress.

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When to Speak to a Doctor Right Away

Do not wait or self-manage if you experience:

• Severe dizziness or fainting
• Signs of infection (fever, pain, confusion)
• Symptoms of DKA
• Trouble urinating or sudden swelling
• Any symptom that feels life-threatening or rapidly worsening

When in doubt, it is always safer to speak to a doctor.

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The Bottom Line

For adults over 65, starting Farxiga is often a positive step toward better heart, kidney, and blood sugar health. The first two weeks are about observation, hydration, and communication—not fear. Most side effects are mild, manageable, and temporary.

By knowing what to watch for, staying in touch with your healthcare provider, and acting early when something feels off, you give Farxiga the best chance to work safely and effectively for you.