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Published on: 2/24/2026

Is Your Hematocrit Abnormal? Why Your Blood Is Off & Medically Approved Next Steps

Hematocrit is the percent of your blood made up of red blood cells; low levels often point to anemia or nutrient deficiencies, while high levels are commonly due to dehydration, smoking, altitude, lung or heart disease, or rarer marrow disorders. There are several factors to consider. See below to understand more.

Next steps typically include repeating the test, targeted labs, and treating the cause such as iron or B12 for low, or hydration, smoking cessation, sleep apnea treatment, or phlebotomy for high, with urgent care for red flags like chest pain, stroke signs, severe shortness of breath, or heavy bleeding. Important details that could change your plan are outlined below.

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Explanation

Is Your Hematocrit Abnormal? Why Your Blood Is Off & Medically Approved Next Steps

If you've recently had blood work done and noticed your hematocrit is higher or lower than normal, you're not alone. Hematocrit is a common lab value, but many people aren't sure what it actually means — or how serious an abnormal result might be.

The good news? In many cases, an abnormal hematocrit is treatable. But it can also signal something that needs medical attention. Here's what you need to know.


What Is Hematocrit?

Hematocrit measures the percentage of your blood that is made up of red blood cells.

Red blood cells carry oxygen from your lungs to the rest of your body. If your hematocrit is too low or too high, your body may not be getting the oxygen it needs — or your blood may be thicker than it should be.

Hematocrit is usually part of a complete blood count (CBC), a routine blood test.

Normal Hematocrit Ranges (may vary slightly by lab)

  • Adult men: ~41% to 53%
  • Adult women: ~36% to 46%
  • Children: Varies by age

Your doctor will interpret your hematocrit based on your age, sex, medical history, and symptoms.


What Does It Mean If Your Hematocrit Is Low?

A low hematocrit means you have fewer red blood cells than normal. This condition is often associated with anemia.

Common Causes of Low Hematocrit

  • Iron-deficiency anemia (most common cause)
  • Vitamin B12 deficiency
  • Folate deficiency
  • Chronic kidney disease
  • Blood loss (heavy periods, ulcers, injury)
  • Chronic inflammatory diseases
  • Bone marrow disorders

Symptoms of Low Hematocrit

You may experience:

  • Fatigue or weakness
  • Pale skin
  • Shortness of breath
  • Dizziness
  • Cold hands and feet
  • Headaches
  • Rapid heartbeat

Sometimes, mild anemia causes no obvious symptoms.

If your hematocrit is low and you're experiencing any of these warning signs, using a free AI-powered Anemia symptom checker can help you understand your symptoms and prepare informed questions before your doctor's appointment.


What Does It Mean If Your Hematocrit Is High?

A high hematocrit means your blood contains a higher percentage of red blood cells than normal. This can make your blood thicker, which may increase the risk of clotting problems in certain cases.

Common Causes of High Hematocrit

  • Dehydration (very common and often temporary)
  • Smoking
  • Living at high altitude
  • Chronic lung disease
  • Heart disease
  • Sleep apnea
  • Polycythemia vera (a rare bone marrow disorder)

Symptoms of High Hematocrit

Some people have no symptoms. Others may experience:

  • Headaches
  • Dizziness
  • Blurred vision
  • Fatigue
  • Flushing of the skin
  • Itching (especially after a hot shower)

In more serious cases, thickened blood can increase the risk of:

  • Blood clots
  • Stroke
  • Heart attack

That said, many elevated hematocrit results are mild and related to dehydration or lifestyle factors.


How Serious Is an Abnormal Hematocrit?

It depends on:

  • How far outside the normal range it is
  • Whether you have symptoms
  • Your overall health
  • Other abnormal lab results

A slightly abnormal hematocrit is often not an emergency. But significant abnormalities — especially with symptoms — require medical evaluation.

Seek immediate medical care if you have:

  • Chest pain
  • Sudden shortness of breath
  • Signs of stroke (facial drooping, slurred speech, weakness)
  • Severe dizziness or fainting
  • Unusual or heavy bleeding

These could signal a serious complication.


Why Would Your Hematocrit Suddenly Change?

Changes in hematocrit can happen due to:

  • Dehydration (can falsely elevate levels)
  • Recent illness
  • Pregnancy
  • Blood loss
  • Changes in kidney function
  • New medications
  • Nutritional deficiencies

Sometimes a repeat test shows that the level has normalized.


Medically Approved Next Steps

If your hematocrit is abnormal, here's what doctors typically recommend.

1. Repeat the Test

Mild abnormalities are often rechecked to confirm accuracy. Hydration status alone can affect results.

2. Additional Blood Tests

Your doctor may order:

  • Hemoglobin level
  • Iron studies
  • Vitamin B12 and folate levels
  • Reticulocyte count
  • Kidney function tests
  • Erythropoietin level
  • Oxygen saturation

These help identify the root cause.

3. Treat the Underlying Cause

Treatment depends on what's causing the abnormal hematocrit.

For Low Hematocrit

  • Iron supplements (if iron deficiency)
  • Vitamin B12 or folate supplements
  • Treating underlying bleeding
  • Managing chronic disease
  • In severe cases, blood transfusion

For High Hematocrit

  • Hydration
  • Smoking cessation
  • Treating sleep apnea
  • Managing lung or heart disease
  • Therapeutic phlebotomy (in specific conditions like polycythemia vera)

Never start supplements without medical guidance — too much iron, for example, can be harmful.


Lifestyle Factors That Affect Hematocrit

Some everyday habits influence your hematocrit level:

Hydration

Not drinking enough fluids can temporarily raise hematocrit.

Smoking

Smoking increases red blood cell production due to reduced oxygen delivery.

High Altitude

Living at high elevation naturally increases hematocrit.

Nutrition

Low iron, B12, or folate intake can reduce red blood cell production.


When Should You Speak to a Doctor?

You should discuss your hematocrit results with a healthcare professional if:

  • Your level is outside the normal range
  • You have symptoms
  • You have a chronic medical condition
  • You are pregnant
  • You have a family history of blood disorders

Even if you feel fine, abnormal blood work deserves proper evaluation.

If anything could be serious or life‑threatening, speak to a doctor immediately or seek urgent medical care.


The Bottom Line

An abnormal hematocrit level is a signal — not a diagnosis.

  • Low hematocrit often points to anemia or nutrient deficiencies.
  • High hematocrit may be caused by dehydration, smoking, altitude, or more serious conditions.
  • Many causes are treatable once identified.
  • Some cases require urgent care.

The key is identifying the underlying reason.

If your hematocrit is abnormal, don't panic — but don't ignore it either. Review your symptoms, and if you're concerned about anemia-related issues, try Ubie's free AI-powered Anemia symptom checker to gain personalized insights before scheduling a conversation with your doctor to determine next steps.

Your blood work is valuable information. With the right follow‑up, most hematocrit issues can be addressed safely and effectively.

(References)

  • * Kaushansky K. Anemia: evaluation and management. Blood. 2023 Feb 16;141(7):696-708. doi: 10.1182/blood.2022018894. PMID: 36737397.

  • * Lopez A, Cacoub P, Macdougall IC, Peyrin-Biroulet M. Iron deficiency anemia: pathophysiology, diagnosis, and treatment. Am J Hematol. 2016 Nov;91(11):1141-1150. doi: 10.1002/ajh.24459. Epub 2016 Aug 29. Erratum in: Am J Hematol. 2019 Feb;94(2):E65. PMID: 27486071.

  • * Swerdlow PS, Steensma DP, Jamieson C, Mesa RA. Polycythemia vera: 2021 update on diagnosis, risk stratification and management. Am J Hematol. 2021 Mar;96(3):362-378. doi: 10.1002/ajh.26083. Epub 2020 Dec 28. PMID: 33366904.

  • * Spivak JL. Secondary erythrocytosis: Clinical approach to diagnosis and management. Blood. 2014 Jan 2;123(1):154-8. doi: 10.1182/blood-2013-11-536034. PMID: 24430154.

  • * Piva R, Piva N, Piva E. The complete blood count: a comprehensive review of its components and relevance to disease states. Clin Chem Lab Med. 2015 Apr;53(5):671-89. doi: 10.1515/cclm-2014-0708. PMID: 25691167.

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