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Published on: 12/11/2025
You generally can’t make a stye disappear overnight, but you can quickly reduce pain and swelling with frequent warm compresses (10–15 minutes, 3–5 times/day), gentle lid hygiene, stopping makeup/contacts, and, when appropriate, an antibiotic ointment or prescription azithromycin 1% eye drops—never squeeze it. Most clear in 7–10 days; seek care sooner for worsening redness/swelling, vision changes, or fever. There are several factors and options (including when to use oral antibiotics or drainage) that could change your next steps—see the complete guidance below.
A stye (hordeolum) is a tender, red bump on the eyelid margin caused by a bacterial infection of an eyelash follicle or oil gland. It can be external (on the lid edge) or internal (within the eyelid). While you may see some improvement overnight, fully “getting rid of a stye overnight” is rarely realistic. However, the right steps can dramatically reduce pain, swelling, and redness by morning—and set you on the fastest path to complete healing.
Warm compresses
Lid hygiene
Over-the-counter (OTC) ointments
Avoidance of irritants
Natural adjuncts (limited evidence)
For moderate to severe styes, or if there’s no improvement after 48 hours of home care, prescription options can accelerate recovery:
Topical azithromycin 1% eye drops
• Jia et al. (2010) found that azithromycin 1% drops twice daily for 7 days improved resolution rates of internal hordeolum compared to placebo, with minimal side effects. (PubMed ID: 20960022)
• Ask your doctor if these drops are appropriate for you.
Topical antibiotic/steroid combinations
• In cases of significant swelling, a combined antibiotic-steroid ointment may reduce inflammation and fight bacteria.
• Only use under direct medical supervision.
Oral antibiotics
• If the infection spreads beyond the eyelid or in immunocompromised individuals, your doctor may prescribe oral antibiotics (e.g., doxycycline or cephalexin).
• Generally reserved for large, painful internal styes or preseptal cellulitis.
Incision and drainage
• For persistent, well-defined styes not responding to conservative treatment, an eye doctor (ophthalmologist) can perform a minor in-office procedure to drain the lesion safely.
Hands-off approach
• Resist rubbing or touching your eye.
• If you accidentally touch your stye, wash hands immediately.
Sleep elevation
• Prop your head up with an extra pillow to reduce fluid accumulation and swelling around the eyes.
Hydration and nutrition
• Stay hydrated and maintain a balanced diet rich in vitamins A and C to support immune function and skin health.
Clean linens and towels
• Change pillowcases and towels regularly to limit reinfection.
Even with diligent home care, certain signs warrant prompt medical attention:
If you’re unsure how serious your symptoms are, you might consider doing a free, online symptom check for an initial assessment. This is not a substitute for professional care but can help you decide whether to seek in-person treatment sooner.
While completely eliminating a stye overnight is unlikely, following the steps above can significantly reduce discomfort and speed healing. Warm compresses, gentle lid hygiene, and appropriate antibiotic therapy (such as azithromycin 1% eye drops) form the cornerstone of effective care. Avoid squeezing the lesion, keep the area clean, and protect it from irritants.
Always monitor for warning signs—if the stye worsens or you experience vision changes, fever, or spreading redness, speak to a doctor about anything that could be life threatening or serious. With consistent treatment and proper medical guidance, most styes resolve fully within 7–10 days.
(References)
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