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Published on: 11/6/2025
Does ibuprofen cause stomach ulcers?
Yes, ibuprofen can cause stomach ulcers, especially if taken frequently or in high doses. See below to understand more.
Concerned about ibuprofen and stomach ulcers?
Explanation
Ibuprofen is a type of medicine called a nonsteroidal anti-inflammatory drug (NSAID). According to research, like the study by Scheiman et al., NSAIDs, including ibuprofen, can increase the risk of stomach ulcers. This happens because these drugs can irritate the stomach lining.
Key Points
- Risk Factors: Taking ibuprofen often or in large amounts can increase the chance of getting stomach ulcers.
- Protective Measures: Some studies, like the one by Bello et al., suggest that certain combinations of medicines can help protect the stomach while taking NSAIDs.
Conclusion
If you need to take ibuprofen regularly, it might be a good idea to talk to a healthcare provider about ways to protect your stomach. They might suggest taking the lowest effective dose or using additional medications to help reduce the risk of ulcers.
(References)
- Scheiman JM, Cryer B, Kimmey MB, Rothstein RI, Riff DS, & Wolfe MM. (2004). A randomized, controlled comparison of ibuprofen at the .... Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 15067622.
- Bello AE, Kent JD, & Holt RJ. (2015). Gastroprotective efficacy and safety of single-tablet .... The Physician and sportsmedicine, 26165391.
- Hawkey CJ. (2000). Nonsteroidal anti-inflammatory drug gastropathy. Gastroenterology, 10930388.
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