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Published on: 2/4/2026

The "Skin Tag" Secret: The Surprising Physical Signs of Insulin Resistance

Multiple skin tags, especially in friction areas like the neck, armpits, or groin, can be an early outward sign of insulin resistance, which is linked to high insulin, rising blood sugar, dark velvety skin patches, abdominal weight gain, and higher risks for type 2 diabetes and heart disease. There are several factors and next steps to consider, including which lab tests to request, lifestyle changes that improve insulin sensitivity, and when to see a clinician; see below for complete details that could influence your healthcare plan.

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Explanation

The “Skin Tag” Secret: The Surprising Physical Signs of Insulin Resistance

Skin tags are often brushed off as harmless, cosmetic annoyances. Many people notice them in places like the neck, armpits, or groin and never give them a second thought. But in some cases, these small growths can be a visible clue to something happening deeper inside the body—Insulin Resistance.

This article explains what skin tags may be telling you, how they connect to Insulin Resistance, and what practical steps you can take to protect your long-term health. The goal is to inform and empower—not to alarm.


What Is Insulin Resistance?

Insulin Resistance happens when your body’s cells stop responding well to insulin, a hormone that helps move sugar (glucose) from your blood into your cells for energy.

When insulin doesn’t work properly:

  • The pancreas produces more insulin to compensate
  • Blood sugar levels may slowly rise
  • The body remains in a high-insulin state for years

Over time, Insulin Resistance can increase the risk of:

  • Type 2 diabetes
  • Heart disease
  • Fatty liver disease
  • Polycystic ovary syndrome (PCOS)
  • Certain skin changes, including skin tags

This process often develops quietly, without obvious symptoms at first.


What Are Skin Tags?

Skin tags, medically called acrochordons, are:

  • Small, soft, flesh-colored or slightly darker growths
  • Usually painless and non-cancerous
  • Common in adults, especially after age 30

They most often appear in areas where skin rubs together, such as:

  • Neck
  • Armpits
  • Groin
  • Under the breasts
  • Eyelids

While friction plays a role, research shows that Insulin Resistance is a significant underlying factor for many people.


The Link Between Skin Tags and Insulin Resistance

Multiple medical studies have found a strong association between skin tags and Insulin Resistance, even in people who do not yet have diabetes.

Why Does This Happen?

When insulin levels stay high for long periods:

  • Insulin acts as a growth-promoting hormone
  • Skin cells and connective tissue may grow more rapidly
  • This can lead to the formation of skin tags

High insulin levels also affect other growth factors in the body, increasing skin cell turnover and thickening.

What Research Has Shown

Credible medical research has found that people with multiple skin tags are more likely to have:

  • Elevated fasting insulin levels
  • Higher blood sugar readings
  • Increased waist circumference
  • Abnormal cholesterol levels

In short, skin tags can be a visible marker of metabolic stress, not just a skin issue.


Other Physical Signs That May Appear Alongside Skin Tags

Skin tags rarely appear alone when Insulin Resistance is involved. Other physical signs may include:

  • Darkened skin patches (acanthosis nigricans)
    • Velvety, darker skin often on the neck or armpits
  • Weight gain around the abdomen
    • Especially weight that is hard to lose
  • Fatigue after meals
    • Feeling sleepy or sluggish after eating carbohydrates
  • Frequent hunger or sugar cravings
  • High blood pressure
  • Elevated triglycerides or low HDL (“good”) cholesterol

Not everyone with Insulin Resistance will have all these signs, but patterns matter.


Who Is More Likely to Develop Insulin Resistance?

Insulin Resistance can affect people of all sizes and ages, but certain factors increase risk:

  • Family history of type 2 diabetes
  • Sedentary lifestyle
  • Chronic stress or poor sleep
  • Diet high in refined carbohydrates and added sugars
  • Hormonal conditions such as PCOS
  • History of gestational diabetes

Skin tags may be one of the earliest outward signs—sometimes appearing years before diabetes develops.


Why Early Awareness Matters

The good news is that Insulin Resistance is often reversible, especially when caught early.

Addressing it early can:

  • Reduce the risk of type 2 diabetes
  • Improve energy levels
  • Support heart and liver health
  • Decrease the formation of new skin tags

Ignoring the signs doesn’t make the issue go away—it just delays treatment.


What You Can Do If You Notice Skin Tags

If you’ve developed multiple skin tags, especially alongside other symptoms, it may be worth checking in on your metabolic health.

Practical Next Steps

  • Track patterns, not just one symptom
  • Consider blood tests such as fasting glucose, HbA1c, and fasting insulin
  • Review lifestyle habits, including sleep, movement, and diet

You may also want to consider doing a free, online symptom check for Medically approved LLM Symptom Checker Chat Bot to help organize your symptoms before speaking with a healthcare professional.


Lifestyle Changes That Support Insulin Sensitivity

Small, consistent changes can make a meaningful difference.

Nutrition

  • Focus on whole foods: vegetables, lean protein, healthy fats
  • Reduce sugary drinks and refined carbs
  • Eat balanced meals that include protein and fiber

Movement

  • Aim for regular physical activity, even walking
  • Strength training improves insulin sensitivity
  • Avoid sitting for long, uninterrupted periods

Sleep and Stress

  • Aim for 7–9 hours of quality sleep
  • Manage stress through relaxation techniques or mindfulness
  • Chronic stress can worsen Insulin Resistance

These changes are not about perfection—they are about progress.


Should Skin Tags Be Removed?

Removing skin tags may improve comfort or appearance, but it does not treat Insulin Resistance itself.

Important points:

  • Skin tag removal does not address the underlying cause
  • New skin tags may continue to form if insulin levels remain high
  • Medical removal is safest, especially for uncertain growths

Always have new or changing skin growths evaluated by a medical professional.


When to Speak to a Doctor

You should speak to a doctor if:

  • Skin tags appear suddenly or increase rapidly
  • You also experience symptoms like extreme fatigue, excessive thirst, or frequent urination
  • You have a family history of diabetes or heart disease
  • Any skin growth is painful, bleeding, or changing in color

Anything that could be life-threatening or serious should always be discussed with a qualified healthcare professional as soon as possible.


The Bottom Line

Skin tags are common and usually harmless—but they can sometimes be an early, visible sign of Insulin Resistance. Paying attention to these small physical clues gives you a chance to act before more serious health problems develop.

You don’t need to panic, and you don’t need to ignore them either. Awareness, informed choices, and professional guidance can make a real difference.

If you’re unsure what your symptoms might mean, consider starting with a free symptom check for Medically approved LLM Symptom Checker Chat Bot and then follow up by speaking to a doctor about your results.

Your skin may be telling you a story—listening early can help protect your future health.

(References)

  • * Karthikeyan K, et al. Acrochordons and insulin resistance. Indian J Dermatol Venereol Leprol. 2011 May-Jun;77(3):362-5. doi: 10.4103/0378-6323.79728. PMID: 21508595.

  • * Rukhsana S, et al. Association of acrochordons with insulin resistance, metabolic syndrome, and other cardiovascular risk factors. J Pak Assoc Dermatol. 2017;27(4):307-313.

  • * Erkek E, et al. Acrochordons: potential clinical marker for insulin resistance. J Clin Exp Dermatol Res. 2013;4(5):1000185.

  • * Katsogianni M, et al. Cutaneous manifestations of metabolic syndrome. World J Diabetes. 2021 Mar 15;12(3):284-301. doi: 10.4239/wjd.v12.i3.284. PMID: 33767897; PMCID: PMC7986064.

  • * Hasler P, et al. Cutaneous manifestations of insulin resistance. Clin Dermatol. 2004 Nov-Dec;22(6):534-42. doi: 10.1016/j.clindermatol.2004.07.017. PMID: 15680145.

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