Which blood test is used to check for iron deficiency anemia in multiple myeloma patients?

Reviewed by Yoshinori Abe, MD

Internal Medicine

Iron deficiency anemia in people with multiple myeloma is typically diagnosed through blood tests. The most common tests include serum ferritin, which measures stored iron, and reticulocyte hemoglobin content (CHr), which reflects recent iron availability for red blood cell production. Together, these tests help doctors confirm iron deficiency and guide treatment decisions.

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Reviewed for medical accuracy: 07/14/2026

Important Next Steps

Learn if iron deficiency anemia needs care Discover likely causes of your anemia Find out if multiple myeloma is possible See OTC options for anemia symptoms Find a hematologist for anemia care Understand home remedies for iron deficiency Check if your anemia needs urgent care

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Explanation

Iron deficiency anemia can be checked using specific blood tests. Serum ferritin is a common test that helps show how much iron is stored in the body. Another useful test is the reticulocyte hemoglobin content (CHr), which looks at the hemoglobin in young red blood cells to see if there is enough iron. These tests help doctors understand if a person has iron deficiency anemia, even if they have a condition like multiple myeloma.

Key Tests:

Serum Ferritin: Measures iron storage in the body
Reticulocyte Hemoglobin Content (CHr): Checks iron levels in new red blood cells

These tests are important because they help doctors decide if a person needs more iron in their diet or through supplements. If you're experiencing symptoms that concern you, you can check your symptoms to better understand what might be causing them. These blood tests are especially useful for people with conditions like multiple myeloma, where iron levels need to be carefully monitored.

(References)

Naghii MR, & Fouladi AI. (2006). Correct assessment of iron depletion and iron deficiency .... Nutrition and health, 16859176.
Higgins C. (1995). Deficiency testing for iron, vitamin B12 and folate. Nursing times, 7603852.
Stoffman N, Brugnara C, & Woods ER. (2005). An algorithm using reticulocyte hemoglobin content (CHr) .... The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 15909357.

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