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Published on: 2/24/2026
Stomach burning can be a peptic ulcer, most often from H. pylori infection or frequent NSAID use; classic signs are gnawing upper-abdominal pain that changes with meals, though reflux, gastritis, gallbladder issues, or pancreatitis can feel similar.
Key next steps include seeing a clinician for H. pylori testing and possible endoscopy, using acid-reducing medication and antibiotics if indicated, and getting urgent care for vomiting blood, black stools, or sudden severe pain; there are several factors to consider, so see the complete guidance below for details that could change your next steps.
A burning feeling in your stomach can be uncomfortable, distracting, and sometimes scary. You may wonder: Is it just heartburn—or could it be an ulcer?
An ulcer is an open sore that forms in the lining of the stomach or the first part of the small intestine (duodenum). When it happens in the stomach, it's called a gastric ulcer. When it happens in the small intestine, it's called a duodenal ulcer. Together, these are known as gastroduodenal ulcers or peptic ulcers.
Let's break down what causes an ulcer, how to recognize it, and what steps you should take next.
Your stomach produces acid to help digest food. Normally, a protective layer of mucus shields your stomach lining from that acid. When this protective barrier breaks down, acid can damage the tissue underneath. Over time, that damage can form an ulcer.
Helicobacter pylori (H. pylori) infection
A common bacterial infection that weakens the stomach's protective lining.
Frequent use of NSAIDs
Medications like ibuprofen, naproxen, and aspirin can irritate and thin the stomach lining.
Smoking
Heavy alcohol use
Severe physical stress (such as major illness, burns, or surgery)
Less commonly, certain medical conditions that increase acid production can lead to ulcers.
The classic symptom of an ulcer is burning or gnawing pain in the upper abdomen, often between the breastbone and belly button.
However, ulcer symptoms can vary.
Some people have no symptoms at all until complications develop.
Not all stomach burning is an ulcer. Other common causes include:
Because symptoms overlap, guessing isn't reliable. If you're experiencing persistent burning pain and want clarity on whether it could be an ulcer, try this free Gastroduodenal Ulcer symptom checker to get personalized insights and guidance on your next steps.
Still, no online tool replaces professional medical evaluation.
Most ulcers are treatable. However, untreated ulcers can lead to complications, some of which are life-threatening.
These may be signs of:
These are medical emergencies. Do not delay care.
If your symptoms suggest an ulcer, a doctor may recommend:
This can be done through:
A thin, flexible tube with a camera is passed through your mouth into your stomach. This allows direct visualization of the ulcer and, if needed, a biopsy.
In some cases, imaging studies may be used to evaluate complications.
An endoscopy is often recommended if you:
The good news: Most ulcers heal with proper treatment.
Treatment typically lasts 10–14 days.
Healing usually takes:
It's critical to complete the full course of antibiotics if prescribed. Stopping early can lead to recurrence and antibiotic resistance.
While medication is essential, lifestyle adjustments help reduce irritation and prevent recurrence.
There's no strict "ulcer diet," but if certain foods worsen symptoms (spicy, acidic, fried), limiting them can help you feel better.
Most ulcers do not turn into cancer.
However:
This is not meant to alarm you. It's simply a safety measure to ensure proper diagnosis.
Occasional heartburn after a heavy meal is common. But ongoing or worsening burning pain is not something to ignore.
You should speak to a doctor if:
Early treatment prevents complications and speeds healing.
If you're concerned your symptoms may indicate a Gastroduodenal Ulcer, a quick online assessment can help you understand your risk and what to do next.
Most importantly, speak to a doctor about persistent stomach pain, especially if you experience warning signs like bleeding, black stools, fainting, or severe abdominal pain. These could indicate a life-threatening condition and require urgent medical care.
Burning stomach pain is common—but it's never something you should ignore when it persists. With proper evaluation and treatment, most ulcers heal completely, and you can get back to feeling like yourself again.
(References)
* Lau JY, Leung WK, Wu JC, Sung JJ. Peptic ulcer disease. Lancet. 2021 Jul 3;398(10294):40-52.
* Moayyedi P, Lacy BE, Andrews CN, et al. ACG Clinical Guideline: Management of Dyspepsia. Am J Gastroenterol. 2017 Jul;112(7):991-1002.
* Malfertheiner P, Megraud F, Rokkas T, et al. Management of Helicobacter pylori infection: the Maastricht V/Florence Consensus Report. Gut. 2017 Jan;66(1):6-30.
* Chait MM, Maity C, Sen T, et al. NSAID-induced Gastropathy: A Comprehensive Review. J Clin Transl Hepatol. 2023 Apr 28;11(2):373-380.
* Ford AC, Mahadeva S, Talley NJ. Functional Dyspepsia. Gastroenterology. 2017 Jul;153(1):9-27.
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