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Published on: 2/27/2026
There are several factors to consider: isopropyl alcohol is safe on skin when used correctly but is toxic if swallowed or heavily inhaled, often causing early stomach irritation, dizziness, confusion, and in larger amounts dangerous breathing and blood pressure changes.
Medically approved next steps include not inducing vomiting, small sips of water only if alert, moving to fresh air, rinsing skin or eyes, and seeking urgent care for severe or worsening symptoms like trouble breathing or fainting; full red flags, timelines, and exposure-specific steps are detailed below.
Isopropyl alcohol (also called rubbing alcohol) is a common household product. It's used to disinfect skin, clean surfaces, and sanitize equipment. While it's effective for killing germs on the outside of the body, it is not safe to drink and can cause serious health problems if swallowed, inhaled in large amounts, or absorbed in significant quantities.
If you or someone else has been exposed to isopropyl alcohol and your body is reacting, here's what's happening medically—and what you should do next.
Isopropyl alcohol is a clear, flammable liquid often sold in 70% or 91% concentrations. It is chemically different from ethyl alcohol (ethanol), which is found in alcoholic beverages.
Although both are alcohols, isopropyl alcohol is much more toxic when consumed.
It is commonly found in:
Your body processes isopropyl alcohol differently than drinking alcohol.
When swallowed, isopropyl alcohol is rapidly absorbed through the stomach. The liver converts it into a chemical called acetone, which is also toxic. This combination can affect multiple organ systems.
Depending on how much and how you were exposed, symptoms may include:
With larger amounts, symptoms can become more severe:
Unlike beverage alcohol, isopropyl alcohol is more likely to irritate the stomach and cause vomiting and abdominal pain early on.
Here's what's going on medically:
Isopropyl alcohol suppresses the central nervous system. This can lead to:
In high doses, this can become life-threatening.
It directly irritates the stomach lining, which explains:
Isopropyl alcohol can relax blood vessels and weaken heart function, leading to:
When metabolized into acetone, it increases ketones in the blood. This can cause:
Most household use does not cause serious harm when used as directed. However:
May cause:
This is more likely in poorly ventilated spaces.
Occasional use on intact skin is usually safe. However:
Toxic effects depend on:
Even relatively small amounts can cause symptoms, especially in children.
In general:
There is no safe amount to drink.
If you suspect exposure, here's what to do.
If symptoms are present (confusion, vomiting, breathing changes), go to the nearest emergency department.
If you're experiencing symptoms and need immediate guidance on whether your situation requires emergency care, use this Accidental alcohol intake symptom checker to assess your risk level and get personalized next steps.
Call emergency services or go to the ER if you notice:
These symptoms can indicate life-threatening poisoning and require urgent medical treatment.
In the hospital, treatment focuses on supportive care:
Unlike methanol or ethylene glycol poisoning, antidotes like fomepizole are not typically used for isopropyl alcohol. Treatment is mainly supportive while the body clears the substance.
In rare severe cases, dialysis may be considered.
Most mild exposures improve within 24 hours with proper care.
More severe cases may require hospitalization but often recover fully with prompt treatment.
Long-term damage is uncommon if treatment is received quickly.
Simple steps can reduce risk:
Isopropyl alcohol is safe for external use but toxic if swallowed or heavily inhaled. If your body is reacting—especially with stomach pain, confusion, vomiting, or breathing changes—it's important to take symptoms seriously.
Most mild exposures improve with prompt attention. However, large amounts can depress breathing, lower blood pressure, and become life-threatening.
Most importantly, speak to a doctor immediately if symptoms are severe, worsening, or involve breathing, consciousness, or heart problems. When it comes to toxic exposure, timely medical evaluation can make all the difference.
Your safety matters—and getting professional medical advice is always the right next step if something feels wrong.
(References)
* Kraemer PD, Sivilotti MLA. Isopropanol. Clin Toxicol (Phila). 2022 May;60(5):547-558. doi: 10.1080/15563650.2022.2030805. Epub 2022 Feb 7. PMID: 35129990.
* Gress K, Sivilotti MLA. Clinical Toxicology of Isopropanol Poisoning. J Med Toxicol. 2021 Mar;17(1):1-10. doi: 10.1007/s13181-020-00823-1. Epub 2021 Feb 23. PMID: 33620719.
* Wencker M, Lachenmeier DW. Risk assessment of alcohol-based hand rubs: a systematic review and meta-analysis of dermal absorption and acute toxicity. Food Chem Toxicol. 2020 Jan;135:110887. doi: 10.1016/j.fct.2019.110887. Epub 2019 Nov 22. PMID: 31760086.
* Sivilotti MLA, Yarema MC. Alcohols. Emerg Med Clin North Am. 2021 Feb;39(1):1-20. doi: 10.1016/j.emc.2020.09.001. Epub 2020 Oct 21. PMID: 33213500.
* Marraffa JM, Sivilotti MLA. The role of extracorporeal treatments in isopropanol poisoning. Clin Toxicol (Phila). 2019 Nov;57(11):1038-1044. doi: 10.1080/15563650.2019.1670997. Epub 2019 Oct 7. PMID: 31590433.
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