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Published on: 7/15/2026

Could multiple myeloma be causing me to feel lightheaded when I stand up?

Yoshinori Abe

Reviewed by Yoshinori Abe, MD

Internal Medicine

Lightheadedness when standing up is not typically a direct symptom of multiple myeloma. However, multiple myeloma can cause anemia, kidney problems, or high blood calcium, all of which may indirectly lead to dizziness or lightheadedness upon standing. If you experience this symptom frequently, it's important to consider a broader range of possible causes, including dehydration, low blood pressure, medication side effects, or other underlying conditions.

Because dizziness when standing can stem from many different issues, the smartest next step is to identify what's actually driving your symptoms. A free, instant, online symptom check can help you quickly narrow down possible causes, understand your risk level, and guide you toward the right next steps—whether that means self-care, seeing a doctor, or seeking urgent evaluation. Taking a few minutes now could save you time, worry, and unnecessary guesswork.

Reviewed for medical accuracy: 07/14/2026

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Important Next Steps

Discover if lightheadedness could signal multiple myelomaLearn whether your standing dizziness needs careSee likely causes of lightheadedness when standingFind OTC options for lightheadedness reliefFind doctors for multiple myeloma symptomsExplore home remedies for standing lightheadednessUnderstand if these symptoms need urgent care

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Explanation

From the references given, there is no direct mention of multiple myeloma causing lightheadedness when standing. However, lightheadedness can occur due to changes in blood flow when you stand up.

  1. Blood Flow and Posture: One study discusses blood flow changes in the brain when you stand up, which might cause lightheadedness. This can happen if the blood flow is not fast enough to adjust to the new position.

  2. Other Causes: Balance problems and dizziness can happen after neck surgery, but this is different from what you asked about.

  3. Unrelated Conditions: Another reference talks about symptoms from a liver condition, which is not related to multiple myeloma.

If you are worried about feeling lightheaded, you can use Ubie's free AI symptom checker to help identify potential causes and determine if you should speak with a doctor.

(References)

  • Mathew RJ, Wilson WH, Humphreys D, Lowe JV, & Wiethe KE. (1992). Middle cerebral artery velocity during upright posture after .... Acta psychiatrica Scandinavica, 1529742.

  • Newton JL. (2010). Systemic symptoms in non-alcoholic fatty liver disease. Digestive diseases (Basel, Switzerland), 20460914.

  • Hermansen A, Peolsson A, Hedlund R, & Kammerlind AS. (2020). Balance problems and dizziness after neck surgery. Physiotherapy theory and practice, 30686102.

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