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Published on: 10/9/2026
A lobotomy was a form of psychosurgery, popularized in the 1930s through the 1950s, in which a surgeon severed the nerve connections linking the prefrontal cortex to the rest of the brain in an attempt to calm severe mental illness such as schizophrenia, depression, and agitation. It is no longer performed because the results were unpredictable and frequently devastating, causing permanent personality change, apathy, seizures, incontinence, and in some cases death, and because the arrival of antipsychotic medications in the 1950s, along with modern informed-consent and ethical standards, made the practice both unnecessary and indefensible. There are several important historical and medical distinctions to consider, including how today's precisely targeted neurosurgical treatments differ from lobotomy, so read the complete answer below before drawing conclusions.
If you or someone you care about is struggling with mood, memory, thinking, or behavior changes, you deserve answers grounded in current medicine rather than fear of outdated procedures, and the first step is simply understanding what your symptoms may indicate. Take a free, instant, online symptom check to clarify what might be going on and get guidance on the right next steps and the right kind of care.
Last reviewed for medical accuracy: 10/08/2026
A lobotomy was a form of psychosurgery introduced in the early 20th century to treat severe mental illnesses. The term “lobotomy” comes from the Greek words lobos (“lobe”) and tomē (“cutting”), literally meaning “cutting of a lobe.” In practice, it involved severing or scraping away connections in the brain’s prefrontal cortex—the region behind the forehead responsible for decision-making, emotional regulation, and social behavior.
Prefrontal (standard) lobotomy
Transorbital lobotomy
Post-operative care
Physicians hoped lobotomy would:
However, outcomes varied widely:
Positive reports (in some cases):
Common negative effects:
By the late 1950s, lobotomy fell out of favor for multiple reasons:
Introduction of psychiatric medications
Unpredictable and often debilitating side effects
Evolving ethical standards
Advances in psychotherapy and alternative treatments
By the 1970s, virtually all psychiatric associations had condemned lobotomy. Today, it is considered an obsolete and unethical practice.
The history of lobotomy highlights critical principles in medicine:
Rigorous clinical trials
Any new treatment must undergo controlled studies to assess safety and efficacy.
Patient rights and informed consent
Individuals must understand potential risks and benefits before undergoing irreversible procedures.
Holistic care
Mental health treatment should combine medication, therapy, social support, and respect for patient autonomy.
While lobotomy meaning remains an important chapter in psychiatric history, current treatments focus on:
If you’re experiencing symptoms such as persistent sadness, overwhelming anxiety, unusual thoughts or behaviors, you might consider a free, online symptom check, using the doctor approved Ubie Symptom Checker to better understand what you’re experiencing.
If you or someone you know is facing severe or worsening mental health symptoms—especially thoughts of self-harm, inability to care for oneself, or sudden personality changes—always seek professional help right away. Only a qualified doctor can provide a full assessment and recommend the safest, most effective treatment.
Summary
A lobotomy was a surgical procedure aimed at disrupting brain circuits thought to cause severe mental illness. Once widespread, it is no longer performed due to unpredictable outcomes, high risk of permanent harm, and the advent of safer, more effective treatments. If you have concerns about your mental health, use tools like the Ubie Symptom Checker and speak directly with a healthcare provider.
(References)
* Williams M. Psychosurgery. Br J Perioper Nurs. 2002 Dec;12(12):443-8. doi: 10.1177/175045890201201202. PMID: 12572400.
* Stewart DG, Davis KL. The lobotomist. Am J Psychiatry. 2008 Apr;165(4):457-8. doi: 10.1176/appi.ajp.2008.08020174. PMID: 18381916.
* Elias WJ, Cosgrove GR. Psychosurgery. Neurosurg Focus. 2008;25(1):E1. doi: 10.3171/FOC/2008/25/7/E1. PMID: 18590377.
* Luigjes J, de Kwaasteniet BP, de Koning PP, Oudijn MS, van den Munckhof P, Schuurman PR, Denys D. Surgery for psychiatric disorders. World Neurosurg. 2013 Sep-Oct;80(3-4):S31.e17-28. doi: 10.1016/j.wneu.2012.03.009. Epub 2012 Mar 30. PMID: 22465369.
* Temel Y, Lim LW. Neurosurgical treatments of depression. Curr Top Behav Neurosci. 2013;14:327-39. doi: 10.1007/7854_2012_222. PMID: 22865464.
* Cleary DR, Ozpinar A, Raslan AM, Ko AL. Deep brain stimulation for psychiatric disorders: where we are now. Neurosurg Focus. 2015 Jun;38(6):E2. doi: 10.3171/2015.3.FOCUS1546. PMID: 26030702.
* Bertolote JM. Egas Moniz: twice a double life. Arq Neuropsiquiatr. 2015 Oct;73(10):885-6. doi: 10.1590/0004-282X20150138. PMID: 26465405.
* Rzesnitzek L, Hariz M, Krauss JK. The Origins of Human Functional Stereotaxis: A Reappraisal. Stereotact Funct Neurosurg. 2019;97(1):49-54. doi: 10.1159/000496157. Epub 2019 Feb 13. PMID: 30759450.
* Mithani K, Meng Y, Abrahao A, Mikhail M, Hamani C, Giacobbe P, Lipsman N. Electroencephalography in Psychiatric Surgery: Past Use and Future Directions. Stereotact Funct Neurosurg. 2019;97(3):141-152. doi: 10.1159/000500994. Epub 2019 Aug 14. PMID: 31412334.
* Warsi N, Thiong'o GM, Zuccato J, Ibrahim GM. Multiple hippocampal transections: Post-operative Memory Outcomes and Seizure Control. Epilepsy Behav. 2019 Nov;100(Pt A):106496. doi: 10.1016/j.yebeh.2019.106496. Epub 2019 Oct 23. PMID: 31654940.
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