Low Albumin? Why Your Body Is Losing Protein & Medically Approved Next Steps

If you've been told you have low albumin, it's natural to wonder what that means and how serious it is. Albumin is one of the most important proteins in your blood. When levels drop, it can be a signal that something deeper is going on in your body.

The good news? Low albumin is often treatable once the root cause is identified. The key is understanding why your body is losing protein — and what to do next.

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What Is Albumin?

Albumin is a protein made by your liver. It plays several essential roles:

• Keeps fluid from leaking out of blood vessels
• Carries hormones, vitamins, and medications through your bloodstream
• Helps maintain proper blood volume and pressure
• Supports tissue growth and repair

Normal blood albumin levels are typically 3.5 to 5.0 grams per deciliter (g/dL). When levels fall below this range, the condition is called hypoalbuminemia.

Low albumin is not a disease itself — it's a sign that something else may be affecting your liver, kidneys, digestive system, or overall nutrition.

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What Causes Low Albumin?

Low albumin usually happens for one of three reasons:

1. Your body isn't making enough
2. You're losing too much
3. Your body is breaking it down faster than usual

Let's look at the most common medically recognized causes.

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1. Liver Disease

Since albumin is made in the liver, liver problems can reduce production.

Common causes:

• Cirrhosis
• Chronic hepatitis
• Severe liver inflammation
• Alcohol-related liver damage

When liver function declines, albumin levels often fall gradually.

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2. Kidney Disease (Protein Loss in Urine)

Healthy kidneys prevent protein from leaking into urine. But in conditions like:

• Nephrotic syndrome
• Chronic kidney disease
• Diabetic kidney disease

Albumin can spill into the urine in large amounts. This leads to swelling (especially in legs and around eyes).

If your doctor suspects this, they'll usually order a urine protein test.

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3. Malnutrition or Poor Protein Intake

Albumin levels can drop if you're not consuming enough protein or calories.

This may happen due to:

• Severe calorie restriction
• Eating disorders
• Chronic illness
• Older age with poor appetite
• Limited access to food

However, in developed countries, low albumin is more often related to illness than diet alone.

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4. Malabsorption or Protein-Losing Gastroenteropathy

Sometimes, you're eating enough protein — but your body isn't absorbing it properly or is losing it through the digestive tract.

This can occur in:

• Inflammatory bowel disease (Crohn's, ulcerative colitis)
• Celiac disease
• Intestinal infections
• Lymphatic disorders
• Certain autoimmune conditions

If you're experiencing chronic diarrhea, bloating, unexplained weight loss, or swelling alongside low albumin, it may be worth checking whether Malabsorption Syndrome or Protein Losing Gastroenteropathy could explain your symptoms — Ubie offers a free AI-powered tool to help you understand what might be happening before your next doctor's visit.

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5. Severe Inflammation or Infection

During serious illness, trauma, or infection, your body shifts priorities. Albumin production may decrease as part of the inflammatory response.

This can occur with:

• Sepsis
• Major burns
• Cancer
• Autoimmune diseases
• Severe COVID-19

In these cases, low albumin often reflects the severity of illness.

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6. Heart Failure

In congestive heart failure, fluid buildup and liver congestion may reduce albumin production and alter fluid balance, leading to swelling.

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Symptoms of Low Albumin

Low albumin itself doesn't always cause symptoms. But when levels drop significantly, you may notice:

• Swelling in legs, ankles, or abdomen
• Puffy eyelids
• Fatigue
• Muscle weakness
• Fluid in the abdomen (ascites)
• Unexplained weight changes

If you experience shortness of breath, chest pain, severe swelling, confusion, or rapid weight gain, seek urgent medical care.

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How Doctors Diagnose the Cause

Finding the cause of low albumin is more important than the number itself.

Your doctor may order:

• Comprehensive metabolic panel (CMP)
• Liver function tests
• Kidney function tests
• Urine protein testing
• Inflammatory markers
• Imaging (ultrasound or CT scan)
• Stool studies (if malabsorption is suspected)

Diagnosis is often a step-by-step process.

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Medically Approved Next Steps

Treatment depends entirely on the underlying cause. Simply "eating more protein" is rarely enough if there's an organ issue involved.

Here's what evidence-based care typically includes:

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✅ 1. Treat the Underlying Condition

• Liver disease → manage hepatitis, reduce alcohol, specialist care
• Kidney disease → blood pressure control, diabetes management, nephrology referral
• Inflammatory bowel disease → anti-inflammatory or immune-modifying medications
• Heart failure → fluid management and cardiac medications

Correcting the root problem often improves albumin levels.

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✅ 2. Optimize Nutrition

If nutrition is contributing, your doctor may recommend:

• 1.0–1.5 grams of protein per kilogram of body weight daily (varies by condition)
• High-quality protein sources (eggs, fish, poultry, legumes, dairy)
• Oral nutrition supplements
• Referral to a registered dietitian

In severe cases, medical nutrition therapy may be required.

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✅ 3. Manage Fluid Balance

If swelling is present:

• Sodium restriction
• Diuretics (if appropriate)
• Monitoring daily weight

Never start diuretics without medical supervision.

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✅ 4. Monitor Albumin Over Time

Albumin is often used as a marker of overall health. Improving levels usually indicates that treatment is working.

Doctors typically recheck levels every few weeks to months depending on severity.

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Can Low Albumin Be Dangerous?

Yes — but context matters.

Mildly low albumin may not cause immediate harm. However, severely low albumin (under 2.5 g/dL) increases risk of:

• Serious swelling
• Infections
• Delayed wound healing
• Complications after surgery
• Increased hospitalization risk

Low albumin is often a sign that the body is under stress. It should never be ignored.

That said, many causes are treatable — especially when caught early.

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When to Speak to a Doctor Immediately

Seek prompt medical attention if you have:

• Rapid swelling
• Severe abdominal bloating
• Shortness of breath
• Yellowing of skin or eyes
• Frothy urine
• Confusion or extreme fatigue

Low albumin linked to liver failure, kidney failure, or severe infection can become life-threatening without proper care.

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The Bottom Line

Low albumin is not just a lab number — it's a signal.

Your body may be:

• Not making enough protein
• Losing it through kidneys or intestines
• Breaking it down during illness
• Not absorbing it properly

The solution is not guesswork. It's identifying and treating the underlying cause.

If you're unsure whether digestive protein loss could be involved, Ubie's free AI-powered symptom checker can help you explore whether Malabsorption Syndrome or Protein Losing Gastroenteropathy might match your experience — giving you valuable context to discuss with your healthcare provider.

Most importantly, speak to a doctor about any abnormal albumin result. Some causes are mild. Others can be serious or even life-threatening if left untreated. Early evaluation gives you the best chance for a straightforward recovery.

With the right diagnosis and medically guided treatment plan, albumin levels often improve — and so does your overall health.