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Published on: 10/30/2025

What exactly happens in the body when someone has lupus?

Lupus is when the body’s immune system mistakenly attacks its own tissues, causing inflammation and damage to various organs. See below to understand more.

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Explanation

Lupus, or systemic lupus erythematosus (SLE), is a disease where the immune system, which usually fights germs, starts attacking the body’s own cells. This can cause inflammation and harm to many parts of the body like the skin, joints, kidneys, and heart.

How Lupus Affects the Body:

  1. Immune System Confusion: In lupus, the immune system gets confused and thinks the body’s own cells are invaders.
  2. Antibody Production: The body makes special proteins called antibodies that attack its own tissues.
  3. Inflammation: This attack causes swelling, redness, and pain in the affected areas.
  4. Organ Damage: Over time, this can lead to damage in organs like the kidneys, skin, and heart.

Why Does This Happen?

  • Genetic Factors: Some people have genes that make them more likely to get lupus.
  • Environmental Triggers: Things like sunlight, infections, or stress can trigger lupus in people who are at risk.

Lupus is a complex disease, and its symptoms can vary widely, making it important to understand and manage it with the help of healthcare professionals.

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Systemic Lupus Erythematosus (SLE)

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