Published on: 4/7/2025
A molar pregnancy is an abnormal growth of tissue instead of a normal baby, usually caused by an error during fertilization. It leads to symptoms such as unusual vaginal bleeding, severe nausea, and a quickly growing uterus.
In a molar pregnancy, something goes wrong when an egg is fertilized. Instead of creating a healthy placenta and baby, the tissue grows abnormally. There are two main types: complete and partial. In a complete molar pregnancy, no normal baby tissue forms at all, while in a partial molar pregnancy, there might be some normal cells mixed with the abnormal tissue. This problem is caused by mistakes in the genetic material when the egg and sperm come together during fertilization. Because of the abnormal growth, the body makes very high levels of pregnancy hormones. This can cause symptoms like unusual vaginal bleeding, severe nausea and vomiting, and a uterus that grows faster than expected. Other signs might include pelvic pain and, in rare cases, problems related to the thyroid because of the high hormone levels. If someone has these symptoms, it is important to see a doctor quickly. Doctors use tests like ultrasounds and blood tests to check if a molar pregnancy is present so that they can help manage the condition safely.
(References)
Joyce CM, Fitzgerald B, McCarthy TV, Coulter J, O'Donoghue K. Advances in the diagnosis and early management of gestational trophoblastic disease. BMJ Med. 2022 Dec 16;1(1):e000321. doi: 10.1136/bmjmed-2022-000321. PMID: 36936581; PMCID: PMC9978730.
Cue L, Farci F, Ghassemzadeh S, et al. Hydatidiform Mole. [Updated 2024 Dec 11]. In: StatPearls [Internet].
Bruce S, Sorosky J. Gestational Trophoblastic Disease. [Updated 2024 Feb 25]. In: StatPearls [Internet].
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