Our Services
Medical Information
Helpful Resources
Published on: 2/25/2026
Persistent muscle pain is rarely just lactic acid; lactate rises during intense exercise when oxygen falls short and clears within 30 to 60 minutes, while soreness days later usually comes from DOMS, overuse, electrolyte issues, infections, medications, or chronic conditions. There are several factors to consider, so see below to understand more.
Seek urgent care for red flags like rapid breathing, confusion, severe weakness, chest pain, or dark urine that could signal lactic acidosis or rhabdomyolysis, and see a doctor if pain lasts over a week or limits daily life; below you will find specific symptoms to watch for, self care tips, ways to reduce lactate during workouts, and the tests clinicians use to guide next steps.
Persistent muscle pain can be frustrating, especially when you're told it's "just lactic acid." While lactic acid does play a role in muscle fatigue during intense activity, it's often misunderstood — and it's rarely the cause of long-lasting muscle pain.
If you're dealing with ongoing soreness, stiffness, or muscle aches (also known as myalgia), it's important to understand what's really happening in your body and when it's time to seek medical advice.
Lactic acid is a substance your body produces when it breaks down glucose (sugar) for energy without enough oxygen available. This typically happens during:
Under these conditions, your body switches to a process called anaerobic metabolism, which results in lactate production. Lactate and hydrogen ions accumulate temporarily in muscle tissue.
Modern research shows that lactic acid itself is not the main cause of muscle soreness the next day. In fact:
Lactic acid builds up when oxygen delivery to muscles can't keep up with energy demands. Common triggers include:
In most healthy people, this buildup is temporary and normal. Your liver and other tissues recycle lactate efficiently once activity slows.
However, in rare cases, excessive lactate production or reduced clearance can lead to lactic acidosis, a serious medical condition. This is not the same as everyday exercise-related muscle fatigue.
If your muscle pain lasts more than a few days, spreads, or occurs without intense exercise, lactic acid is unlikely to be the cause.
Persistent muscle pain may be related to:
This is due to microscopic muscle injury and inflammation — not lactic acid.
Low levels of sodium, potassium, or magnesium can contribute to muscle cramping and soreness.
The flu and other viral illnesses often cause widespread muscle aches.
Certain medications, particularly statins used to lower cholesterol, may cause muscle pain in some individuals.
If your pain is ongoing, unexplained, or worsening, it's worth investigating further with a professional evaluation or using an AI-powered Myalgia (Muscle Pain) symptom checker to help identify potential causes and determine your next steps.
Unlike normal exercise-related lactic acid buildup, lactic acidosis is a medical emergency.
It may cause:
Lactic acidosis can occur due to:
If you experience these symptoms — especially with shortness of breath or confusion — seek emergency medical care immediately.
Occasional soreness is normal. Persistent muscle pain is not something to dismiss.
See a doctor if you notice:
In rare cases, severe muscle breakdown called rhabdomyolysis can occur. This condition requires urgent medical treatment and may cause:
If you speak to a doctor about persistent muscle pain, they may:
Common lab tests may include:
These tests help rule out serious causes and identify underlying conditions.
While lactic acid doesn't cause long-term soreness, you can reduce uncomfortable buildup during workouts by:
Regular training improves your body's ability to clear lactate efficiently.
For non-serious muscle pain, you can try:
Avoid pushing through severe pain. Pain is a signal, not something to ignore.
Here's what's important to understand:
If your muscle pain is mild and related to recent activity, it will likely improve within a few days. But if it's ongoing, unexplained, or severe, don't assume it's just lactic acid.
Getting a clear picture of your symptoms through a free Myalgia (Muscle Pain) assessment can help you understand what might be causing your discomfort and whether you should see a doctor.
Most importantly, speak to a doctor if:
Muscle pain is common — but persistent pain deserves attention. Getting clarity early can help you recover faster and rule out serious conditions.
(References)
* Voermans NC, van Alfen N, de Groot IJM. Metabolic Myopathies. Neuromuscular Disorders. 2017 Mar;27(3):214-222.
* Maes M, Mihaylova I, Leunis JC. Chronic fatigue syndrome and fibromyalgia are characterised by a breakdown of cellular energy production evidenced by reduced ATP/ADP ratios and an upregulation of the AMPK pathway. Mol Neurobiol. 2016 Oct;53(8):5410-23.
* DiMauro S, Garone C, Hirano M. Metabolic myopathies. Handb Clin Neurol. 2018;156:599-623.
* San Juan D, Garcia-Villalon L, Monroy M. Hyperlactatemia: causes, clinical manifestations, diagnosis, and treatment. Am J Health Syst Pharm. 2020 Jan 22;77(3):189-198.
* Parikh S, Goldstein A, Karaa A, Koenig MK, Ng YS, Saneto RP, Woung P, Zolkipli-Cunningham Z, Karaa Z. Diagnosis and Management of Mitochondrial Disease: A Consensus Statement from the Mitochondrial Medicine Society. Genet Med. 2017 Dec;19(12):1283-1291.
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.