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Published on: 8/20/2026
Left-side muscle pain under the ribs is often caused by musculoskeletal or nerve-related conditions. Common causes include:
Because these conditions share overlapping symptoms with more serious issues involving the heart, lungs, spleen, or digestive organs, identifying the true cause matters. The fastest way to narrow it down is to take a free, instant, online symptom check—it uses your specific symptoms to suggest possible causes and recommend the right next steps, so you can decide whether home care, a doctor's visit, or urgent evaluation is appropriate.
Reviewed for medical accuracy: 07/15/2026
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This type of pain might have several causes. One possibility is twelfth rib syndrome, where the last rib becomes irritated and hurts the muscles nearby. Another possibility is intercostal neuralgia. This is when the nerves between your ribs, called intercostal nerves, become irritated or inflamed, causing pain. Painful rib syndrome is another condition, where the area around the rib, including soft tissues and muscles, becomes sore, often because of small injuries or strain. In addition, costochondritis, which is inflammation of the cartilage connecting your ribs to your breastbone, can cause pain under your ribs on one side. Sometimes, the pain might also be due to muscle strain from heavy lifting, awkward movements, or even poor posture. If you continue to have pain, you can use our free symptom checker to help identify possible causes, and it's important to talk to your doctor so they can determine the cause and help you feel better.
(References)
Cranfield KA, Buist RJ, Nandi PR, Baranowski AP. The twelfth rib syndrome. J Pain Symptom Manage. 1997 Mar;13(3):172-5. doi: 10.1016/s0885-3924(96)00271-0. PMID: 9114637.
Fazekas D, Doroshenko M, Horn DB. Intercostal Neuralgia. [Updated 2023 Aug 14]. In: StatPearls [Internet].
Scott EM, Scott BB. Painful rib syndrome--a review of 76 cases. Gut. 1993 Jul;34(7):1006-8. doi: 10.1136/gut.34.7.1006. PMID: 8344569; PMCID: PMC1374244.
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