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Published on: 4/7/2025

What Causes Discoloration of the Nail Bed, and How Can It Be Treated?

Discoloration of the nail bed can be a result of medications (for example, minocycline), fungal infections, or pigment changes. Treatment depends on the cause and may involve stopping a medication, using antifungal creams, or simply monitoring if it is a harmless pigment change.

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Explanation

When the nail bed changes color, it can happen for a few reasons. One cause is medication use. For example, minocycline, an antibiotic, may cause the nail bed and skin to become discolored. Another reason is a fungal infection, where the nail may turn dull yellow or brown. In some cases, a condition called melanonychia leads to extra pigment building up in the nail, which might show as a band or overall darkening. Sometimes, simple injuries or repeated minor trauma can also make the nail look darker. Treating nail bed discoloration depends on what is causing it. If it is due to medication, your doctor might decide to change your treatment. For a fungal infection, topical or oral antifungal medicines may be used to clear up the problem. For pigment changes that are benign, the doctor might only monitor them, especially if they do not cause any discomfort. It’s important to have a healthcare provider look at any new or changing nail discoloration to decide on the best treatment plan.

(References)

  • Abdullah L, Abbas O. Common nail changes and disorders in older people: Diagnosis and management. Can Fam Physician. 2011 Feb;57(2):173-81. PMID: 21321168; PMCID: PMC3038811.

  • Tavares J, Leung WW. Discoloration of nail beds and skin from minocycline. CMAJ. 2011 Feb 8;183(2):224. doi: 10.1503/cmaj.091498. Epub 2010 Nov 22. PMID: 21098068; PMCID: PMC3033929.

  • Singal A, Bisherwal K. Melanonychia: Etiology, Diagnosis, and Treatment. Indian Dermatol Online J. 2020 Jan 13;11(1):1-11. doi: 10.4103/idoj.IDOJ_167_19. PMID: 32055501; PMCID: PMC7001389.

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