Published on: 4/7/2025
Numbness in your left breast might happen when nerves in the area are affected by treatments like surgery or chemotherapy, or sometimes by the cancer itself.
When someone has breast cancer or is treated for it, nerves in the breast area can sometimes get hurt. For example, if you have surgery such as a mastectomy, some nerves might be cut or damaged, which can lead to numbness. This change in feeling is common because the nerves that help you sense touch might not work as well after surgery. Also, some medicines used for treating breast cancer, called chemotherapy drugs, can affect nerves elsewhere in the body, causing what we call chemotherapy-induced neuropathy. This means your brain might not receive the usual signals from the breast area. In some cases, the cancer itself might affect the nerves near it, leading to a loss of sensation. It is important to speak with your doctor about any unusual feelings or changes. They can check your health, review your treatments, and help decide if the numbness is related to treatment changes or something else. Understanding the cause can help guide any necessary steps to make you feel better.
(References)
Qin X, Cao Y. Prognostic Biomarker NUMB Is Inhibited by Breast Cancer Cell Exosomes to Promote Breast Cancer Progression. J Immunol Res. 2022 Apr 18;2022:6032076. doi: 10.1155/2022/6032076. PMID: 35478938; PMCID: PMC9038436.
Lindau ST, Pinkerton EA, Abramsohn EM, Fuller CM, Grubb D, Mendoza T, Siston AK. Importance of Breast Sensation After Mastectomy: Evidence from Three Sources. Womens Health Rep (New Rochelle). 2023 Dec 4;4(1):594-602. doi: 10.1089/whr.2023.0106. PMID: 38099078; PMCID: PMC10719638.
Zhi WI, Chen P, Kwon A, Chen C, Harte SE, Piulson L, Li S, Patil S, Mao JJ, Bao T. Chemotherapy-induced peripheral neuropathy (CIPN) in breast cancer survivors: a comparison of patient-reported outcomes and quantitative sensory testing. Breast Cancer Res Treat. 2019 Dec;178(3):587-595. doi: 10.1007/s10549-019-05416-4. Epub 2019 Aug 27. PMID: 31456070; PMCID: PMC6819268.
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Purpose and positioning of servicesUbie Doctor’s Note is a service for informational purposes, and the provision of information by physicians, medical professionals, etc. is not a medical practice. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.