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Published on: 7/15/2026
Omeprazole is a proton pump inhibitor commonly prescribed to reduce stomach acid and relieve acid reflux, GERD, and heartburn symptoms. While it's effective for many people, omeprazole can sometimes cause a persistent dry cough as a side effect. In other cases, a cough may signal that acid reflux is still occurring despite treatment, or point to an unrelated condition entirely.
Because a lingering cough can have many overlapping causes—medication side effects, reflux, allergies, infections, or something else—it's important to identify the root issue before adjusting your treatment. A free, instant, online symptom check can help you narrow down possible causes in minutes and guide you on the best next steps, whether that's speaking with your doctor or exploring lifestyle changes.
Reviewed for medical accuracy: 07/15/2026
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Submit your own QuestionOmeprazole is a medication that reduces the amount of acid in the stomach. This can help with symptoms of acid reflux, which might include nighttime choking if the acid reaches the throat. However, one of the references provided mentions a case where omeprazole caused a persistent cough.
If you experience any unusual symptoms while taking omeprazole, consider using a free symptom checker to help identify what might be causing your symptoms and talk to a healthcare provider.
(References)
Vanderhoof JA, Moran JR, Harris CL, Merkel KL, & Orenstein SR. (2003). Efficacy of a pre-thickened infant formula: a multicenter, .... Clinical pediatrics, 12921449.
Howaizi M, & Delafosse C. (2003). Omeprazole-induced intractable cough. The Annals of pharmacotherapy, 14565840.
Johnson T, Gerson L, Hershcovici T, Stave C, & Fass R. (2010). Systematic review: the effects of carbonated beverages on .... Alimentary pharmacology & therapeutics, 20055784.
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