Our Services
Medical Information
Helpful Resources
Published on: 2/25/2026
Deep, constant, throbbing pain in one bone, especially with swelling, warmth, redness, or fever, can be osteomyelitis, a serious bone infection that needs prompt medical evaluation with blood tests, imaging, and sometimes a biopsy.
Effective, medically approved treatment usually involves 4 to 6 weeks of antibiotics, sometimes surgery, and faster care improves outcomes, especially if you have diabetes, a wound, or recent surgery. There are several factors to consider; see the complete next steps, urgent red flags, and prevention guidance below.
Deep, persistent bone pain is not something to ignore. While many aches are caused by muscle strain or joint inflammation, pain that feels deep, throbbing, or constant—especially if it doesn't improve—can sometimes signal a bone infection known as osteomyelitis.
Osteomyelitis is a serious medical condition, but with early diagnosis and proper treatment, most people recover well. Below, we'll explain what osteomyelitis is, why it happens, what symptoms to watch for, and what medically approved next steps look like.
Osteomyelitis is an infection in a bone. It can be caused by bacteria or, less commonly, fungi. The infection may:
Bones are living tissue with blood supply. When bacteria reach the bone, they can multiply and trigger inflammation. If not treated promptly, this inflammation can damage bone tissue.
Osteomyelitis can affect anyone, but risk is higher in:
Pain from osteomyelitis often has specific characteristics:
In some cases, other symptoms may appear:
In children, osteomyelitis often affects long bones like the leg or arm. In adults, it more commonly affects the spine, feet (especially in people with diabetes), or hips.
Not everyone will have a fever. In fact, chronic osteomyelitis may develop slowly with mild symptoms at first.
Understanding the cause helps explain why prompt care matters.
A skin infection, urinary infection, or respiratory infection can spread bacteria through the blood to the bone. This is more common in children.
Open fractures, deep puncture wounds, or surgery can introduce bacteria directly into bone tissue.
Conditions like diabetes or peripheral artery disease reduce blood flow. When circulation is poor, the body has a harder time fighting infection, increasing the risk of osteomyelitis.
Bone infections can damage bone structure if untreated. In severe cases, complications may include:
This is not meant to alarm you—but to highlight why deep, persistent bone pain should be evaluated promptly. The earlier osteomyelitis is treated, the better the outcome.
If a doctor suspects osteomyelitis, they may recommend:
Checking for swelling, tenderness, warmth, and range of motion.
To look for signs of infection and inflammation.
In certain situations, a small sample of bone may be taken to identify the specific bacteria causing the infection. This helps guide the most effective antibiotic treatment.
If you're experiencing deep bone pain and want to better understand whether your symptoms align with osteomyelitis, you can use a free AI-powered symptom checker for Osteomyelitis to assess your risk before scheduling a doctor's visit.
Treatment depends on how severe the infection is and how long it has been present.
Most cases of osteomyelitis require:
Treatment often lasts 4 to 6 weeks, and sometimes longer for chronic cases.
It is extremely important to complete the full course of antibiotics—even if symptoms improve early.
Surgery may be necessary if:
Surgical procedures may include:
Modern surgical techniques have significantly improved recovery rates.
If diabetes, circulation problems, or immune disorders are present, managing these conditions is critical to healing and preventing recurrence.
Yes. Osteomyelitis can become chronic if:
Chronic osteomyelitis may flare up periodically and require repeated treatment. However, many people live normal lives after proper care.
You should speak to a doctor promptly if you experience:
Seek urgent care if you have:
These could signal a spreading infection and require emergency attention.
If you're experiencing deep bone pain, consider these steps:
If you're uncertain whether your symptoms warrant immediate medical attention, try using a free Osteomyelitis symptom checker to help evaluate your situation and determine the appropriate next steps.
Osteomyelitis is a bone infection that can cause deep, persistent pain and requires prompt medical treatment. While it is a serious condition, early diagnosis and appropriate antibiotics—or surgery when needed—lead to good outcomes for most people.
The key points to remember:
If you suspect osteomyelitis or have symptoms that concern you, speak to a doctor as soon as possible. Any condition involving infection can become serious or life-threatening if ignored. Getting professional medical advice is always the safest step.
Your body is very good at signaling when something isn't right. If deep bone pain persists, listen to it—and get it checked.
(References)
* Singh G, Kaur R, Dhillon DS, Gill S. Osteomyelitis: A Review of Pathophysiology, Clinical Features, and Management. J Clin Diagn Res. 2016 Jan;10(1):LE01-LE05. doi: 10.7860/JCDR/2016/16383.7088. Epub 2016 Jan 1. PMID: 26949755; PMCID: PMC4740645.
* Metsemakers WJ, Morgenstern M, McNally MA, Moriarty TF, McFadyen I, Underwood M, O'Donnell Y, Nowotarski P, Sheldon M, Romano CL, Lipsky BA, Kates SL; International Consensus Group on Osteomyelitis (ICGO). Current concepts in the diagnosis and management of chronic osteomyelitis. J Bone Joint Surg Am. 2018 Sep 5;100(17):1539-1550. doi: 10.2106/JBJS.17.00695. PMID: 30180053.
* Soliman S, Hamed M, Moustafa A, Mansour M, Al-Attar A, Gad Y. Diagnosis and Treatment of Osteomyelitis in Adults: A Systematic Review. Infect Drug Resist. 2022 Jul 25;15:4249-4267. doi: 10.2147/IDR.S372295. PMID: 35911462; PMCID: PMC9331826.
* Conterno L, Ibiapina AM. Acute and chronic osteomyelitis: Diagnosis and management. Rev Assoc Med Bras (1992). 2023;69(1):e20230001. doi: 10.1590/1806-9282.20230001. PMID: 36729583.
* Lima AL, Guerra MT. Diagnosis and management of osteomyelitis. Rev Assoc Med Bras (1992). 2023;69(1):128-135. doi: 10.1590/1806-9282.20220677. PMID: 36729575.
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.