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Published on: 11/26/2025

Do oxymetazoline nasal sprays worsen symptoms if used too long?

Using oxymetazoline nasal sprays for too long can cause your nose to become more blocked, a condition called rhinitis medicamentosa.

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Explanation

Using oxymetazoline nasal sprays for an extended period can cause a condition known as rhinitis medicamentosa. This happens because the nasal spray can lead to a rebound effect, where your nose becomes more congested after the medication wears off.

Here are some key points:

  1. Rebound Congestion: Prolonged use of oxymetazoline nasal spray can cause the blood vessels in the nose to become less responsive, leading to increased congestion when the spray is not used.

  2. Short-term Use Recommended: It is generally advised to use oxymetazoline nasal spray for no more than three to five days to avoid this problem.

  3. Possible Solution: According to research, using a nasal steroid like fluticasone can help reverse the congestion caused by long-term use of oxymetazoline.

To avoid worsening symptoms, it is best to follow the recommended usage instructions for nasal sprays and consult a healthcare professional if you experience persistent congestion.

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