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Published on: 12/17/2025

Could swollen lymph nodes cause a female’s pain under the right armpit?

Yes—swollen axillary lymph nodes can cause pain under the right armpit in women, often tender and worse with arm movement, and most commonly linked to infections, recent vaccinations, or minor injuries. Seek prompt care if a lump is hard, fixed, rapidly enlarging, >2 cm, or accompanied by fever, night sweats, weight loss, or breast changes; imaging like ultrasound and mammography may be used. There are several factors to consider; see below for other possible causes, home assessment tips, supportive care, and when in-person evaluation or biopsy may be needed.

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Explanation

Could swollen lymph nodes cause a female’s pain under the right armpit?

Swollen (enlarged) lymph nodes in the axilla (armpit) are a common source of discomfort and sometimes pain. In women, understanding when a swollen node is benign versus when it warrants further evaluation can help you take appropriate action without unnecessary anxiety.

Anatomy and Function of Axillary Lymph Nodes

  • Lymph nodes filter fluid (lymph) and trap bacteria, viruses, and abnormal cells.
  • The axilla contains 20–40 lymph nodes that drain the arm, chest wall, and breast tissue.
  • When these nodes react to infection or inflammation, they can enlarge and become tender.

How Swelling Leads to Pain

  • Capsules around lymph nodes stretch as they fill with immune cells.
  • Local inflammation releases chemicals that stimulate pain receptors.
  • Pain often worsens with arm movement or pressure on the armpit.

Common Benign Causes

  1. Local skin or soft-tissue infections
    • Insect bites, boils, or cellulitis on the arm or chest wall
    • Signs: redness, warmth, fever
  2. Upper respiratory infections
    • Colds, flu, throat infections
    • May cause generalized lymph node enlargement
  3. Recent vaccinations
    • Vaccines for COVID-19, flu, or tetanus can trigger temporary swelling
  4. Minor injuries or muscle strain
    • Pectoral or shoulder muscle overuse
    • Pain often feels deeper in muscle rather than a discrete lump

When to Consider Imaging
According to Ko et al. (2013), imaging can help distinguish benign from suspicious axillary nodes:

  • Ultrasound (US)
  • Mammography (for breast-related concerns)
  • MRI (in select cases)

Features suggesting a benign node on US include:

  • Oval shape with an intact fatty hilum
  • Thin cortex (<3 mm)
  • No abnormal blood flow patterns

Red Flags That Need Prompt Medical Attention
If you have any of the following, speak to a doctor without delay:

  • A hard, fixed lump that persists > 2 – 4 weeks
  • Rapidly growing node
  • Unexplained weight loss, night sweats, or persistent fevers
  • Significant breast changes (nipple discharge, skin dimpling)
  • Widespread lymph node enlargement (neck, groin)

Less Common—but Serious—Causes
• Breast cancer metastasis to axillary nodes
• Lymphoma (Hodgkin’s or non-Hodgkin’s)
• Tuberculosis or other systemic infections

Other Possible Causes of Right-Side Armpit Pain in Women

  • Muscular strain (rotator cuff, chest wall)
  • Referred pain from rib injury or gallbladder disease
  • Shingles (herpes zoster) before rash appears
  • Hidradenitis suppurativa (chronic inflammatory skin condition)

Assessing Your Symptoms at Home
Ask yourself:

  • Do I have fever, chills, or signs of infection?
  • Is the lump moveable or fixed in place?
  • Am I experiencing any breast changes?
  • Does arm movement make it worse or better?

If you’re unsure, consider doing a free, online “symptom check for pain under right armpit female” to help clarify your next steps.

When to Seek In-Person Care
• Severe, worsening pain that limits arm use
• Signs of systemic infection (high fever, feeling unwell)
• Lymph node > 2 cm or continuously enlarging
• Any red flags listed above

What to Expect at Your Doctor’s Visit

  • Physical exam of the armpit, breast, and nearby lymph node regions
  • Blood tests (complete blood count, inflammatory markers)
  • Imaging (ultrasound, mammogram, MRI if indicated)
  • Possible biopsy if malignancy is suspected

Preventive and Supportive Measures

  • Warm compresses to ease discomfort
  • Over-the-counter pain relievers (ibuprofen or acetaminophen)
  • Rest and elevating the arm when possible
  • Treat any obvious skin infections promptly

Key Takeaways

  • Yes, swollen lymph nodes can cause a female’s pain under the right armpit.
  • Most cases are benign and related to infections or minor injuries.
  • Persistent, hard, or rapidly growing nodes need evaluation.
  • Imaging (US, mammography, MRI) helps rule out serious conditions (Ko et al., 2013).
  • Always “speak to a doctor” about life-threatening or serious red-flag symptoms.

If you experience any severe, persistent, or worrying symptoms, please speak to a doctor as soon as possible. Your health and peace of mind are too important to delay professional evaluation.

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