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Published on: 2/27/2026

Painful Swallowing? Why Esophagitis Is Inflaming Your Throat and Medically Approved Next Steps

Painful swallowing is often from esophagitis, an inflammation of the esophagus caused by acid reflux, eosinophilic allergy, irritating medications, or infections, and it can feel like burning, chest pain, or food getting stuck.

Medically approved next steps include evaluation with endoscopy and biopsy when needed, targeted treatments such as PPIs for reflux, swallowed steroids or diet changes for eosinophilic disease, adjusting culprit medications, and antifungal or antiviral therapy for infections, plus supportive lifestyle changes. Seek urgent care for food impaction, inability to swallow liquids, severe chest pain, or bleeding; there are several factors to consider, so see the complete details below to guide your next steps.

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Explanation

Painful Swallowing? Why Esophagitis Is Inflaming Your Throat and Medically Approved Next Steps

Painful swallowing can feel alarming. If it burns when you eat, hurts when you drink, or feels like food is getting stuck, esophagitis may be the cause.

Esophagitis is inflammation of the esophagus—the muscular tube that carries food from your mouth to your stomach. When this lining becomes irritated or damaged, swallowing can become painful and uncomfortable.

The good news? Most cases of esophagitis are treatable. But it's important to understand what's causing it and when to seek medical care.


What Is Esophagitis?

Esophagitis occurs when the lining of the esophagus becomes inflamed. This inflammation can result from:

  • Stomach acid backing up into the esophagus
  • Allergic reactions
  • Infections
  • Certain medications
  • Physical injury or irritation

Over time, untreated esophagitis can lead to complications such as narrowing (strictures), ulcers, bleeding, or scarring. In rare cases, chronic inflammation may increase the risk of more serious conditions.

That's why recognizing the symptoms early matters.


Common Symptoms of Esophagitis

Symptoms can range from mild to severe. Some people experience only discomfort, while others have significant pain.

Typical symptoms include:

  • Painful swallowing (odynophagia)
  • Difficulty swallowing (dysphagia)
  • A burning sensation in the chest (heartburn)
  • Chest pain, especially after eating
  • Food feeling stuck in the throat or chest
  • Regurgitation of food or sour liquid
  • Chronic cough
  • Hoarseness or sore throat

Children may show different signs, such as feeding difficulties, vomiting, or poor weight gain.

If swallowing becomes severely painful or you cannot swallow liquids, seek urgent medical care.


The Main Types of Esophagitis

Understanding the type of esophagitis is key to proper treatment.

1. Reflux Esophagitis (GERD-Related)

This is the most common form. It happens when stomach acid frequently flows back into the esophagus (acid reflux or GERD).

Over time, acid damages the lining, causing inflammation.

Risk factors include:

  • Obesity
  • Pregnancy
  • Smoking
  • Large or late-night meals
  • Hiatal hernia

2. Eosinophilic Esophagitis (EoE)

Eosinophilic esophagitis is a chronic immune condition. It occurs when a type of white blood cell (eosinophil) builds up in the esophagus, often in response to food allergens or environmental triggers.

Symptoms may include:

  • Difficulty swallowing
  • Food impaction (food getting stuck)
  • Chest pain
  • Persistent reflux that doesn't improve with acid medication

If these symptoms sound familiar, you can use a free AI-powered Eosinophilic Esophagitis symptom checker to assess your risk and get personalized guidance before your doctor's appointment.

3. Medication-Induced Esophagitis

Certain pills can irritate the esophagus if they don't pass quickly into the stomach.

Common culprits:

  • NSAIDs (like ibuprofen)
  • Certain antibiotics
  • Potassium supplements
  • Iron supplements
  • Some osteoporosis medications

Taking pills without enough water or lying down immediately afterward increases risk.

4. Infectious Esophagitis

More common in people with weakened immune systems, this form is caused by:

  • Fungal infections (like Candida)
  • Viral infections (such as herpes simplex)
  • Bacterial infections (rare)

It can cause severe pain and difficulty swallowing.


Why Painful Swallowing Happens

When the esophagus becomes inflamed:

  • The lining swells
  • Nerve endings become more sensitive
  • Acid or food passing through triggers pain

In some cases, inflammation can cause narrowing of the esophagus. This can lead to food getting stuck—a medical situation that may require urgent care.

Painful swallowing should never be ignored if it persists or worsens.


How Doctors Diagnose Esophagitis

If symptoms continue for more than a few days or interfere with eating, a doctor may recommend testing.

Common diagnostic tools include:

  • Upper endoscopy (EGD): A small camera is used to look at the esophagus and take biopsies.
  • Biopsy: Tissue samples can confirm eosinophilic esophagitis or infection.
  • pH monitoring: Measures acid levels in the esophagus.
  • Barium swallow X-ray: Helps detect narrowing or structural problems.

Biopsy is especially important for diagnosing eosinophilic esophagitis, as it cannot be confirmed by symptoms alone.


Medically Approved Treatments for Esophagitis

Treatment depends on the underlying cause.

For Reflux Esophagitis

  • Proton pump inhibitors (PPIs) to reduce acid production
  • H2 blockers
  • Lifestyle changes (see below)
  • In severe cases, surgery may be considered

For Eosinophilic Esophagitis

  • Swallowed topical corticosteroids
  • Dietary elimination of trigger foods
  • Biologic therapies (for certain patients)
  • Esophageal dilation (if narrowing occurs)

For Medication-Induced Esophagitis

  • Stopping or switching the medication
  • Taking pills with a full glass of water
  • Remaining upright for at least 30 minutes after taking medications

For Infectious Esophagitis

  • Antifungal medications
  • Antiviral therapy
  • Treatment of underlying immune issues

Treatment is often highly effective when started early.


Lifestyle Changes That Support Healing

For many people, simple changes can significantly reduce symptoms of esophagitis.

Helpful habits include:

  • Eating smaller, more frequent meals
  • Avoiding late-night eating
  • Staying upright for 2–3 hours after meals
  • Limiting trigger foods (spicy, acidic, fatty foods)
  • Reducing caffeine and alcohol
  • Quitting smoking
  • Maintaining a healthy weight
  • Elevating the head of the bed

These steps are particularly helpful for reflux-related esophagitis.


When to Seek Immediate Medical Care

While esophagitis is often manageable, certain symptoms require urgent evaluation.

Seek emergency care if you experience:

  • Food stuck in your throat that won't pass
  • Inability to swallow liquids
  • Severe chest pain
  • Vomiting blood
  • Black or tarry stools
  • Signs of dehydration

Always speak to a doctor about symptoms that are severe, worsening, or potentially life threatening.


Can Esophagitis Lead to Complications?

Yes, especially if untreated.

Potential complications include:

  • Esophageal strictures (narrowing)
  • Ulcers
  • Bleeding
  • Chronic scarring
  • Barrett's esophagus (a precancerous condition linked to long-term acid damage)

These outcomes are uncommon when esophagitis is properly diagnosed and treated. That's why early medical attention matters.


The Bottom Line

Painful swallowing is not something you should ignore. Esophagitis is a common and treatable cause, but the type of inflammation determines the right treatment.

If you're experiencing:

  • Persistent heartburn
  • Food getting stuck
  • Ongoing chest discomfort
  • Swallowing pain

It's time to speak with a healthcare professional.

If symptoms suggest an allergic or immune cause, you can start by checking your symptoms with a free AI-powered Eosinophilic Esophagitis assessment tool to help you prepare for a more informed conversation with your doctor.

Most importantly, talk to a doctor about any symptoms that feel severe, persistent, or concerning. Early treatment can relieve discomfort, prevent complications, and protect your long-term esophageal health.

Painful swallowing has a cause. With proper care, it also has a solution.

(References)

  • * Shah SC, et al. Esophagitis: A Comprehensive Review. J Clin Med. 2023 Jul 26;12(15):4974. doi: 10.3390/jcm12154974. PMID: 37573656.

  • * Dellon ES. Current approaches to the management of esophagitis. Ann N Y Acad Sci. 2023 May;1525(1):153-167. doi: 10.1111/nyas.14959. PMID: 37170889.

  • * Shaheen NJ, et al. AGA Clinical Practice Guideline on the Medical Management of Eosinophilic Esophagitis. Gastroenterology. 2020 Jul;159(1):283-301. doi: 10.1053/j.gastro.2020.04.052. PMID: 32360215.

  • * Singh M, et al. Reflux Esophagitis: An Update. Curr Gastroenterol Rep. 2021 Apr 19;23(6):9. doi: 10.1007/s11894-021-00806-z. PMID: 33877478.

  • * Genta RM, et al. Etiology, Diagnosis, and Management of Esophagitis. Curr Gastroenterol Rep. 2018 Dec 20;20(12):58. doi: 10.1007/s11894-018-0661-0. PMID: 30570642.

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