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Published on: 2/24/2026
Pancreatitis is inflammation of the pancreas that typically causes sudden severe upper abdominal pain that can spread to the back with nausea or vomiting; common triggers are gallstones and alcohol, but high triglycerides, certain medicines, infections, injury, autoimmune disease, and other causes are possible.
Because it can become life-threatening, seek prompt medical care for severe or persistent pain so doctors can confirm it with enzyme blood tests and imaging, give IV fluids, pain control, and bowel rest, and treat the cause such as removing gallstones or stopping alcohol. There are several factors to consider. See below to understand more.
If you're experiencing severe upper abdominal pain, nausea, or vomiting, you may be wondering: Is it pancreatitis?
Pancreatitis is a condition where the pancreas becomes inflamed. It can range from mild and temporary to severe and life-threatening. Knowing the signs, causes, and medical next steps can help you act quickly and confidently.
This guide explains what pancreatitis is, why it happens, what symptoms to look for, and what to do next—based on trusted medical evidence and clinical guidelines.
The pancreas is a small but powerful organ located behind your stomach. It plays two major roles:
Pancreatitis occurs when digestive enzymes activate too early—while still inside the pancreas—causing inflammation and damage to the organ itself.
There are two main types:
Acute pancreatitis is more common and can sometimes become serious quickly.
The most common symptom of acute pancreatitis is upper abdominal pain. This pain often:
Other symptoms may include:
Chronic pancreatitis may cause:
If pain is severe, persistent, or associated with fever or vomiting, it is important to seek medical care right away.
Several conditions can trigger pancreatitis. The most common causes include:
Gallstones are the leading cause of acute pancreatitis. A gallstone can block the pancreatic duct, trapping digestive enzymes inside the pancreas and triggering inflammation.
Heavy or long-term alcohol use is another major cause. Alcohol can irritate pancreatic cells and interfere with normal enzyme function.
Very high levels of triglycerides (a type of fat in the blood) can inflame the pancreas.
Certain medications may rarely trigger pancreatitis.
Viral infections can sometimes lead to pancreatic inflammation.
Trauma or surgery involving the abdomen can cause damage.
In rare cases, the immune system mistakenly attacks the pancreas.
In some people, no clear cause is found.
Most cases of acute pancreatitis are mild and improve with medical treatment in a few days. However, about 15–20% of cases can become severe.
Severe pancreatitis may lead to:
These complications require urgent medical treatment, often in a hospital setting.
This is why abdominal pain that is severe or persistent should never be ignored.
Doctors diagnose pancreatitis using a combination of:
Classic abdominal pain pattern.
Elevated levels of pancreatic enzymes:
A diagnosis usually requires at least two of the following:
If pancreatitis is suspected, here's what typically happens:
Most people with acute pancreatitis are admitted to the hospital for:
In mild cases, recovery may take just a few days.
Once stabilized, doctors focus on preventing recurrence:
If complications develop, treatment may include:
Prevention depends on the cause, but helpful steps include:
If you've had pancreatitis before, your doctor will help create a personalized prevention plan.
Go to the emergency room or seek urgent care if you have:
Pancreatitis can escalate quickly. Early treatment significantly improves outcomes.
If you're experiencing severe upper abdominal pain that radiates to your back along with nausea or vomiting, you might be dealing with Acute Pancreatitis—take a free symptom assessment to better understand your condition and determine how urgently you should seek care.
While online tools do not replace a medical diagnosis, they can help you better understand your symptoms and decide how urgently to seek care.
If inflammation keeps coming back, it can lead to chronic pancreatitis. Over time, this can cause:
Chronic pancreatitis requires long-term management, including:
Early intervention after the first episode of acute pancreatitis reduces the risk of chronic damage.
Hearing the word pancreatitis can be frightening. It's true that severe cases can be life-threatening. However:
The key is not to ignore symptoms—especially severe abdominal pain.
Pancreatitis is inflammation of the pancreas that can range from mild to severe. The most common signs include sudden upper abdominal pain, nausea, and vomiting. Gallstones and alcohol use are the leading causes, but high triglycerides, medications, and other conditions may also play a role.
If you suspect pancreatitis:
If your symptoms feel intense, worsening, or life-threatening, seek emergency care immediately.
And for any concerning or persistent symptoms, speak to a doctor. Only a healthcare professional can properly diagnose pancreatitis and determine the right treatment plan.
Your health is too important to guess—especially when it comes to the pancreas.
(References)
* Wang G, Li Y, Yang C, et al. Acute pancreatitis: recent advances in diagnosis, imaging and management. J Gastroenterol Hepatol. 2023 Mar;38(3):355-364. doi: 10.1111/jgh.16067. Epub 2022 Nov 20. PMID: 36398335.
* Singh VK, Yadav D. Acute Pancreatitis: Etiology, Pathophysiology, and Management. Gastroenterol Clin North Am. 2022 Mar;51(1):15-32. doi: 10.1016/j.gtc.2021.09.006. Epub 2021 Dec 2. PMID: 35123566; PMCID: PMC8759325.
* Singh VK, Yadav D. AGA Clinical Practice Update on the Management of Acute Pancreatitis: Expert Review. Gastroenterology. 2022 Jan;162(1):315-321. doi: 10.1053/j.gastro.2021.09.027. Epub 2021 Sep 28. PMID: 34592237.
* Pezzilli R, Uomo G, Al-Haddad M, et al. Chronic pancreatitis: update on pathophysiology, imaging, and management. Minerva Gastroenterol. 2023 Mar;69(1):1-16. doi: 10.23736/S2724-5975.22.07221-7. Epub 2022 Nov 17. PMID: 36394541.
* Gukovskaya AS, Gukovsky I, Algül H, et al. Pancreatitis. Lancet. 2020 Jan 25;395(10220):305-323. doi: 10.1016/S0140-6736(19)32971-4. Epub 2019 Jan 10. PMID: 30638520; PMCID: PMC7264875.
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