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Published on: 7/14/2026

Can a lump on the perineum be a sign of cancer, and what are the warning signs to look for?

A lump on the perineum is usually not cancer, but in some cases it can be. Warning signs of a cancerous perineal lump include:

  • Changes in size, shape, or color
  • Persistent pain
  • Bleeding
  • Non-healing sores or lesions

Because these symptoms can overlap with many benign conditions, it's difficult to know the cause without a proper evaluation. Taking a free, instant, online symptom check can help you better understand what may be causing your symptoms and guide you on the right next steps—whether that's monitoring at home or seeing a doctor promptly.

Reviewed for medical accuracy: 07/14/2026

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Explanation

A lump on the perineum, the area between the vagina and anus for females, is most often benign (not cancer) and can be caused by conditions like cysts or infections. However, in rare cases, a lump could be a sign of cancer. Some perineal cancers or aggressive tumors, like aggressive angiomyxoma, may show up as a mass in this area.

Warning signs that suggest you should talk with your healthcare provider include: if the lump grows in size over time, changes shape, or its skin changes color; if it becomes very painful or starts to bleed; or if the lump does not heal over a period of time.

Other signs like discharge or noticeable ulcers around the lump could also be concerning. If you're experiencing any of these symptoms, you can use Ubie's free AI symptom checker to help assess your condition and determine whether you need immediate medical attention. Your doctor will perform a physical examination and may recommend imaging tests, such as an ultrasound or MRI, to get a closer look at the lump. If needed, they might do a biopsy, where a small piece of tissue is taken, to check if cancer cells are present. Early evaluation helps ensure that any serious condition is caught and treated promptly.

(References)

  • Boaz E, Freund MR, Harbi A, Dagan A, Gilshtein H, Reissman P, Yellinek S. Anorectal Malignancies Presenting as a Perianal Abscess or Fistula. Am Surg. 2023 Jun;89(6):2572-2576. doi: 10.1177/00031348221101481. Epub 2022 May 27. PMID: 35621130.

  • Deckers C, Dumitru L, Corbisier F. Perineal aggressive angiomyxoma in a menopausal woman. BMJ Case Rep. 2017 Dec 7;2017:bcr2017222622. doi: 10.1136/bcr-2017-222622. PMID: 29222207; PMCID: PMC5728223.

  • Wang X, Yang H, Zhang H, Shi T, Ren W. Transvaginal sonographic features of perineal masses in the female lower urogenital tract: a retrospective study of 71 patients. Ultrasound Obstet Gynecol. 2014 Jun;43(6):702-10. doi: 10.1002/uog.13251. PMID: 24254259.

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