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Published on: 2/27/2026
A stubborn sore spot on the sole that won’t heal is often a plantar wart from HPV, which grows inward under pressure and lingers if treatment is inconsistent or the diagnosis is wrong. There are several factors to consider; see below to understand how pressure, viral persistence, and your immune status can stall healing and when it might not be a wart.
Medically approved next steps start with daily salicylic acid plus gentle paring and offloading, then office treatments like cryotherapy, cantharidin, immunotherapy, or minor procedures for resistant cases, with urgent care if it’s painful, spreading, bleeding, changing, or if you have diabetes or poor circulation. Full guidance, prevention tips, and how to choose between watchful waiting and treatment are outlined below.
If you have a stubborn sore spot on the bottom of your foot that just won't go away, you might be dealing with a plantar wart. These growths can be frustrating, sometimes painful, and surprisingly persistent. Many people try over-the-counter treatments for weeks—or even months—without seeing improvement.
Here's what you need to know about plantar warts, why they can be hard to heal, and the medically approved next steps that actually work.
A plantar wart is a small growth that appears on the sole (plantar surface) of your foot. It's caused by certain strains of the human papillomavirus (HPV). The virus enters your skin through tiny cuts or weak spots in the bottom of your foot.
Unlike warts on other parts of the body, a plantar wart grows inward because of the pressure from walking and standing. This inward growth is what often causes pain.
Plantar warts are common in children, teens, athletes, and people who use public showers or pools.
It's normal to expect a skin problem to clear up quickly. But a plantar wart often doesn't. Here's why:
The bottom of your foot takes constant pressure. Every step pushes the wart inward. This pressure:
HPV infects the outer layer of your skin. Treatments have to reach and destroy infected cells. If therapy isn't consistent or deep enough, the virus can survive and regrow.
Some people clear a plantar wart quickly. Others don't. Your immune system is a key factor. If your immune response doesn't strongly target the virus, the wart may persist.
This is especially true if you:
Sometimes, what looks like a plantar wart is actually:
If it's not truly a plantar wart, standard wart treatments won't work.
If you're unsure what you're dealing with, you can use a free AI-powered Warts symptom checker to get personalized insights about your symptoms and help determine whether you should seek professional medical care.
Yes, sometimes.
In healthy individuals, many plantar warts resolve without treatment within 1–2 years. However:
Waiting is reasonable if it's not painful and not spreading—but many people prefer active treatment.
If your plantar wart isn't healing, these are evidence-based treatment options doctors commonly recommend.
This is often the first treatment recommended by medical professionals.
Salicylic acid works by:
How to use it effectively:
Consistency matters. It can take 6–12 weeks to see full results.
If home treatment fails, a doctor may use liquid nitrogen to freeze the plantar wart.
Cryotherapy:
It can cause temporary blistering and soreness, but it is generally safe and effective.
Applied in a medical office, cantharidin causes a controlled blister under the wart. This lifts the wart away from the skin.
This method is often used in children because it's typically painless during application.
For stubborn plantar warts, doctors may use treatments that stimulate your immune system, such as:
These treatments are often reserved for warts that resist standard therapy.
In persistent or painful cases, a doctor may recommend:
These are typically considered after other treatments fail, as they may involve scarring or longer healing time.
If your plantar wart won't heal, avoid these common mistakes:
Trying to "dig it out" yourself can cause infection and worsen the problem.
You should speak to a doctor if:
Foot problems in people with diabetes or circulation issues can become serious quickly. Even something that looks minor should be evaluated promptly.
If there is any chance the lesion could represent something more serious, including a skin cancer, do not delay care. While rare, unusual or non-healing lesions should always be medically assessed.
Once you've had a plantar wart, you're slightly more prone to getting another. Reduce your risk by:
Strengthening your overall immune health—through sleep, nutrition, and stress management—may also help.
A plantar wart can be stubborn, uncomfortable, and slow to heal. The virus lives in the skin, and pressure from walking makes treatment harder. While some plantar warts go away on their own, many require consistent treatment.
Start with:
If that doesn't work, medically supervised treatments like cryotherapy or immunotherapy are safe and effective options.
If you're experiencing a persistent foot lesion and want clarity before your next doctor's appointment, try using a free AI-powered Warts symptom checker to understand your symptoms better and get guidance on the appropriate next steps.
And most importantly: Speak to a doctor if the lesion is painful, spreading, bleeding, changing in appearance, or if you have any underlying medical conditions like diabetes. Foot health matters, and persistent skin problems deserve proper medical attention.
With the right approach, even the most stubborn plantar wart can be treated successfully.
(References)
* Ljubenović M, Bjekić M, Stojković-Filipović J. Warts: Current Treatment Options. Curr Med Chem. 2019;26(23):4416-4433. doi: 10.2174/0929867325666180904123847. PMID: 30182604.
* Del Rosso JQ, Del Rosso A, Del Rosso J. Human papillomavirus and plantar warts: an update on epidemiology, pathogenesis and treatment. J Clin Aesthet Dermatol. 2019 Feb;12(2):12-19. PMID: 30881519.
* Abed A, Khachemoune A, Al-Otaibi N. Treatment of Recalcitrant Plantar Warts with Combination Therapy of Topical 5% Fluorouracil and 10% Salicylic Acid: A Retrospective Study. J Cutan Aesthet Surg. 2023 Apr-Jun;16(2):166-170. doi: 10.4103/JCAS.JCAS_365_21. Epub 2023 Apr 28. PMID: 37408466. PMCID: PMC10313137.
* Maranda EL, Nguyen J, Lim VM, Lee P. Emerging therapies for warts. J Am Acad Dermatol. 2016 Oct;75(4):815-22. doi: 10.1016/j.jaad.2016.03.016. Epub 2016 May 19. PMID: 27198754.
* Al-Mutairi N, Al-Khalaf M, Al-Habeeb A, Al-Faraidy N. Immunotherapy of Warts: A Comprehensive Review. J Clin Aesthet Dermatol. 2017 Jul;10(7):36-44. PMID: 28761623. PMCID: PMC5529324.
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