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Published on: 2/27/2026
Racing thoughts often reflect an overactive brain linked to low or disrupted GABA, the brain’s calming brake, and can be driven by anxiety, chronic stress, poor sleep, hormonal shifts, stimulants, or mood disorders. There are several factors to consider; see below for red flags, the mixed evidence on GABA supplements, and which lifestyle steps, CBT, and prescriptions that act on GABA may help.
For next steps, optimize sleep, exercise, slow breathing, and cut stimulants, and see a clinician if symptoms disrupt life, occur with mood swings or impulsivity, or include suicidal thoughts, since evaluation for anxiety, bipolar disorder, thyroid issues, medication effects, or substances can change treatment; complete guidance is below.
If your mind feels like it's stuck in overdrive — jumping from one thought to the next, replaying conversations, imagining worst-case scenarios, or struggling to slow down at night — you're not alone. Racing thoughts are common, especially during times of stress. But when they become persistent, intrusive, or disruptive, it's important to understand what may be happening inside your brain.
One key player in this process is GABA.
Let's break down what GABA is, how it relates to racing thoughts, and what medical next steps may help.
GABA (gamma-aminobutyric acid) is the brain's main calming neurotransmitter. Neurotransmitters are chemical messengers that allow brain cells to communicate. While some neurotransmitters stimulate brain activity, GABA does the opposite — it slows things down.
Think of GABA as your brain's brake pedal.
When GABA levels and function are balanced, you're able to:
When GABA activity is low or not working properly, the brain can feel overstimulated — like a car rolling downhill without brakes. That's when racing thoughts may show up.
Racing thoughts usually reflect a state of increased brain excitability. Several factors can disrupt GABA balance or increase stimulating chemicals like glutamate and norepinephrine.
Common causes include:
Generalized anxiety disorder (GAD), panic disorder, and social anxiety are strongly linked to altered GABA activity. When inhibitory signaling is reduced, the brain stays in "alert mode," even when there is no real danger.
Long-term stress increases cortisol. Elevated cortisol may interfere with GABA signaling and increase excitatory brain activity. The result? Difficulty turning your mind off.
Lack of sleep reduces the brain's ability to regulate neurotransmitters effectively, including GABA. This creates a cycle:
Fluctuations in estrogen and progesterone (such as during PMS, postpartum, or perimenopause) can affect GABA receptors. That's one reason some people notice worsening anxiety during hormonal shifts.
Caffeine, certain medications, and recreational stimulants increase excitatory neurotransmitters. For sensitive individuals, even moderate caffeine can intensify racing thoughts.
Conditions like bipolar disorder may cause periods of rapid thinking, pressured speech, and decreased need for sleep. In these cases, racing thoughts are part of a broader mood pattern and require medical evaluation.
People describe racing thoughts as:
Occasional episodes are normal. Persistent or severe symptoms are not something you should ignore.
If you're experiencing these symptoms and want to understand whether anxiety may be a contributing factor, Ubie's free AI-powered Anxiety Symptom Checker can provide personalized insights in just a few minutes — helping you take the first step toward clarity before speaking with a healthcare professional.
Research consistently shows that GABA dysfunction is linked to anxiety symptoms. Brain imaging studies demonstrate reduced GABA activity in individuals with anxiety disorders.
When GABA signaling is insufficient:
Certain anti-anxiety medications (like benzodiazepines) work by enhancing GABA activity. This supports the scientific connection between GABA and mental overactivity.
However, medication is not the only way to influence GABA.
While the brain is complex, there are evidence-based lifestyle approaches that may help regulate GABA function:
Sleep restores neurotransmitter balance.
Moderate aerobic exercise increases GABA levels and improves stress resilience. Even 20–30 minutes of brisk walking most days can help.
Deep, slow breathing stimulates the parasympathetic nervous system, promoting calm. Try:
Brain imaging studies show meditation may increase GABA activity. It doesn't require perfection — just consistent practice.
If you experience racing thoughts, consider limiting:
Even small reductions can make a difference.
You may see over-the-counter GABA supplements marketed for anxiety. The science is mixed.
The key issue: Oral GABA does not easily cross the blood-brain barrier. Some people report feeling calmer, but high-quality clinical evidence is limited. Supplements are not regulated like prescription medications, and quality varies.
Before starting any supplement, speak to a doctor — especially if you take other medications.
Racing thoughts deserve medical attention if they:
A healthcare professional may evaluate for:
Treatment options may include:
If racing thoughts are severe, worsening, or paired with thoughts of self-harm, speak to a doctor immediately or seek urgent medical care. Serious mental health symptoms should never be ignored.
Racing thoughts usually reflect an overactive brain state, often linked to stress, anxiety, poor sleep, or neurotransmitter imbalance — particularly involving GABA.
GABA acts as your brain's braking system. When it isn't functioning optimally, mental overactivity can follow.
The good news:
Start with simple steps: improve sleep, reduce stimulants, move your body, and practice slow breathing. If you're unsure whether your symptoms may be related to anxiety, try Ubie's free AI-powered Anxiety Symptom Checker for personalized guidance based on your specific experience.
Most importantly, speak to a doctor if symptoms are persistent, severe, or disruptive. Some causes of racing thoughts — including mood disorders or medical conditions — require proper diagnosis and treatment.
An overactive mind can feel exhausting. But with the right support and medical guidance, balance is absolutely possible.
(References)
* Owji SM, Ebrahimi H. A review of the role of GABA in the pathophysiology of anxiety disorders and the clinical efficacy of GABAergic agents. Braz J Pharm Sci. 2022 Dec 22;58:e210138. doi: 10.1590/s2175-97902022e210138. PMID: 36557688.
* LeGates TA, Kvarta MD, Thompson SM. The role of GABAergic dysfunction in the pathophysiology of anxiety disorders. Psychopharmacology (Berl). 2019 Mar;236(3):813-827. doi: 10.1007/s00213-019-05202-z. Epub 2019 Jan 23. PMID: 30671607.
* Maras PM, Baccini M, Raddi M, Chiti L, Ricca V. The neurobiology of anxiety disorders: A review. J Psychiatr Res. 2023 Jan;157:245-257. doi: 10.1016/j.jpsychires.2022.10.043. Epub 2022 Oct 26. PMID: 36262497.
* Ma Q, Yu Y, Liu X, Yang X. The Involvement of the GABAergic System in the Pathophysiology and Treatment of Anxiety Disorders. Front Pharmacol. 2022 Jul 18;13:948924. doi: 10.3389/fphar.2022.948924. PMID: 35928646; PMCID: PMC9339947.
* Kim J, D'Aquino R, Kim D, Lee H. Neural circuits underlying anxiety-related behaviors. Exp Neurobiol. 2021 Jun;30(3):149-161. doi: 10.5607/en.2021.30.3.149. Epub 2021 Jun 22. PMID: 34298132; PMCID: PMC8290520.
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