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Published on: 2/27/2026

Racing Thoughts? Why Your Brain Is Overactive: GABA & Medical Next Steps

Racing thoughts often reflect an overactive brain linked to low or disrupted GABA, the brain’s calming brake, and can be driven by anxiety, chronic stress, poor sleep, hormonal shifts, stimulants, or mood disorders. There are several factors to consider; see below for red flags, the mixed evidence on GABA supplements, and which lifestyle steps, CBT, and prescriptions that act on GABA may help.

For next steps, optimize sleep, exercise, slow breathing, and cut stimulants, and see a clinician if symptoms disrupt life, occur with mood swings or impulsivity, or include suicidal thoughts, since evaluation for anxiety, bipolar disorder, thyroid issues, medication effects, or substances can change treatment; complete guidance is below.

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Explanation

Racing Thoughts? Why Your Brain Is Overactive: GABA & Medical Next Steps

If your mind feels like it's stuck in overdrive — jumping from one thought to the next, replaying conversations, imagining worst-case scenarios, or struggling to slow down at night — you're not alone. Racing thoughts are common, especially during times of stress. But when they become persistent, intrusive, or disruptive, it's important to understand what may be happening inside your brain.

One key player in this process is GABA.

Let's break down what GABA is, how it relates to racing thoughts, and what medical next steps may help.


What Is GABA?

GABA (gamma-aminobutyric acid) is the brain's main calming neurotransmitter. Neurotransmitters are chemical messengers that allow brain cells to communicate. While some neurotransmitters stimulate brain activity, GABA does the opposite — it slows things down.

Think of GABA as your brain's brake pedal.

When GABA levels and function are balanced, you're able to:

  • Relax after stress
  • Fall asleep more easily
  • Stay focused
  • Regulate anxious thoughts
  • Avoid feeling mentally overwhelmed

When GABA activity is low or not working properly, the brain can feel overstimulated — like a car rolling downhill without brakes. That's when racing thoughts may show up.


Why Does the Brain Become Overactive?

Racing thoughts usually reflect a state of increased brain excitability. Several factors can disrupt GABA balance or increase stimulating chemicals like glutamate and norepinephrine.

Common causes include:

1. Anxiety Disorders

Generalized anxiety disorder (GAD), panic disorder, and social anxiety are strongly linked to altered GABA activity. When inhibitory signaling is reduced, the brain stays in "alert mode," even when there is no real danger.

2. Chronic Stress

Long-term stress increases cortisol. Elevated cortisol may interfere with GABA signaling and increase excitatory brain activity. The result? Difficulty turning your mind off.

3. Sleep Deprivation

Lack of sleep reduces the brain's ability to regulate neurotransmitters effectively, including GABA. This creates a cycle:

  • Poor sleep → reduced GABA balance
  • Reduced GABA → more racing thoughts
  • More racing thoughts → worse sleep

4. Hormonal Changes

Fluctuations in estrogen and progesterone (such as during PMS, postpartum, or perimenopause) can affect GABA receptors. That's one reason some people notice worsening anxiety during hormonal shifts.

5. Stimulants

Caffeine, certain medications, and recreational stimulants increase excitatory neurotransmitters. For sensitive individuals, even moderate caffeine can intensify racing thoughts.

6. Mood Disorders

Conditions like bipolar disorder may cause periods of rapid thinking, pressured speech, and decreased need for sleep. In these cases, racing thoughts are part of a broader mood pattern and require medical evaluation.


What Do Racing Thoughts Feel Like?

People describe racing thoughts as:

  • Thoughts moving too fast to control
  • Constant mental chatter
  • Replaying past conversations
  • Imagining worst-case scenarios
  • Jumping rapidly between unrelated ideas
  • Difficulty concentrating
  • Trouble falling asleep due to a "busy brain"

Occasional episodes are normal. Persistent or severe symptoms are not something you should ignore.

If you're experiencing these symptoms and want to understand whether anxiety may be a contributing factor, Ubie's free AI-powered Anxiety Symptom Checker can provide personalized insights in just a few minutes — helping you take the first step toward clarity before speaking with a healthcare professional.


The Role of GABA in Anxiety and Racing Thoughts

Research consistently shows that GABA dysfunction is linked to anxiety symptoms. Brain imaging studies demonstrate reduced GABA activity in individuals with anxiety disorders.

When GABA signaling is insufficient:

  • The amygdala (fear center) becomes overactive
  • Stress responses increase
  • Relaxation becomes harder
  • Thoughts become repetitive and intrusive

Certain anti-anxiety medications (like benzodiazepines) work by enhancing GABA activity. This supports the scientific connection between GABA and mental overactivity.

However, medication is not the only way to influence GABA.


Can You Naturally Support GABA?

While the brain is complex, there are evidence-based lifestyle approaches that may help regulate GABA function:

1. Prioritize Sleep

  • Aim for 7–9 hours nightly
  • Keep a consistent bedtime
  • Limit screens before bed
  • Reduce caffeine after noon

Sleep restores neurotransmitter balance.

2. Exercise Regularly

Moderate aerobic exercise increases GABA levels and improves stress resilience. Even 20–30 minutes of brisk walking most days can help.

3. Practice Slow Breathing

Deep, slow breathing stimulates the parasympathetic nervous system, promoting calm. Try:

  • Inhale for 4 seconds
  • Hold for 4 seconds
  • Exhale for 6 seconds
    Repeat for several minutes.

4. Mindfulness and Meditation

Brain imaging studies show meditation may increase GABA activity. It doesn't require perfection — just consistent practice.

5. Reduce Stimulants

If you experience racing thoughts, consider limiting:

  • Caffeine
  • Energy drinks
  • Nicotine

Even small reductions can make a difference.


What About GABA Supplements?

You may see over-the-counter GABA supplements marketed for anxiety. The science is mixed.

The key issue: Oral GABA does not easily cross the blood-brain barrier. Some people report feeling calmer, but high-quality clinical evidence is limited. Supplements are not regulated like prescription medications, and quality varies.

Before starting any supplement, speak to a doctor — especially if you take other medications.


When Should You See a Doctor?

Racing thoughts deserve medical attention if they:

  • Interfere with sleep regularly
  • Affect work or relationships
  • Cause panic attacks
  • Occur with mood swings or high energy
  • Are accompanied by impulsive behavior
  • Include suicidal thoughts

A healthcare professional may evaluate for:

  • Anxiety disorders
  • Depression
  • Bipolar disorder
  • Thyroid problems
  • Medication side effects
  • Substance-related causes

Treatment options may include:

  • Cognitive behavioral therapy (CBT)
  • Stress management training
  • Prescription medications
  • Sleep treatment strategies

If racing thoughts are severe, worsening, or paired with thoughts of self-harm, speak to a doctor immediately or seek urgent medical care. Serious mental health symptoms should never be ignored.


The Bottom Line

Racing thoughts usually reflect an overactive brain state, often linked to stress, anxiety, poor sleep, or neurotransmitter imbalance — particularly involving GABA.

GABA acts as your brain's braking system. When it isn't functioning optimally, mental overactivity can follow.

The good news:

  • Many cases improve with lifestyle changes
  • Anxiety is treatable
  • Effective therapies and medications exist
  • You don't have to manage it alone

Start with simple steps: improve sleep, reduce stimulants, move your body, and practice slow breathing. If you're unsure whether your symptoms may be related to anxiety, try Ubie's free AI-powered Anxiety Symptom Checker for personalized guidance based on your specific experience.

Most importantly, speak to a doctor if symptoms are persistent, severe, or disruptive. Some causes of racing thoughts — including mood disorders or medical conditions — require proper diagnosis and treatment.

An overactive mind can feel exhausting. But with the right support and medical guidance, balance is absolutely possible.

(References)

  • * Owji SM, Ebrahimi H. A review of the role of GABA in the pathophysiology of anxiety disorders and the clinical efficacy of GABAergic agents. Braz J Pharm Sci. 2022 Dec 22;58:e210138. doi: 10.1590/s2175-97902022e210138. PMID: 36557688.

  • * LeGates TA, Kvarta MD, Thompson SM. The role of GABAergic dysfunction in the pathophysiology of anxiety disorders. Psychopharmacology (Berl). 2019 Mar;236(3):813-827. doi: 10.1007/s00213-019-05202-z. Epub 2019 Jan 23. PMID: 30671607.

  • * Maras PM, Baccini M, Raddi M, Chiti L, Ricca V. The neurobiology of anxiety disorders: A review. J Psychiatr Res. 2023 Jan;157:245-257. doi: 10.1016/j.jpsychires.2022.10.043. Epub 2022 Oct 26. PMID: 36262497.

  • * Ma Q, Yu Y, Liu X, Yang X. The Involvement of the GABAergic System in the Pathophysiology and Treatment of Anxiety Disorders. Front Pharmacol. 2022 Jul 18;13:948924. doi: 10.3389/fphar.2022.948924. PMID: 35928646; PMCID: PMC9339947.

  • * Kim J, D'Aquino R, Kim D, Lee H. Neural circuits underlying anxiety-related behaviors. Exp Neurobiol. 2021 Jun;30(3):149-161. doi: 10.5607/en.2021.30.3.149. Epub 2021 Jun 22. PMID: 34298132; PMCID: PMC8290520.

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