How does ramelteon differ from melatonin supplements in treating REM Sleep Behavior Disorder (RBD)?

Ramelteon is a prescription medication that works by targeting specific receptors in the brain to help regulate the sleep-wake cycle. It has been shown to have beneficial effects on REM Sleep Behavior Disorder (RBD) by potentially reducing the frequency of disruptive sleep behaviors.

On the other hand, melatonin supplements are over-the-counter products that mimic the natural hormone melatonin, which helps regulate sleep. While melatonin supplements can aid in general sleep issues, their effectiveness in specifically treating RBD is less clear.

Key Differences:

1. Prescription vs. Over-the-Counter: Ramelteon requires a doctor's prescription, while melatonin is available over-the-counter.
2. Mechanism of Action: Ramelteon directly targets melatonin receptors in the brain, whereas melatonin supplements increase overall melatonin levels.
3. Efficacy for RBD: Ramelteon may offer specific benefits for RBD, as suggested by research, while melatonin's role is less defined.

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