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Published on: 9/14/2026
Skin tags, particularly when paired with dark velvety patches of skin (acanthosis nigricans), can be an outward sign of elevated insulin, and insulin resistance itself is often reversible through losing 5 to 10 percent of body weight, cutting refined carbohydrates and added sugars, getting 150 minutes of weekly activity that includes resistance training, prioritizing sleep, and in some cases medications such as metformin or GLP-1 agonists. Existing skin tags usually do not vanish on their own and may require removal by a clinician, but improving insulin sensitivity can reduce how many new ones appear. Timelines, useful lab tests like fasting insulin, A1c, and lipid panels, and other possible causes of skin tags differ from person to person, so there are several important factors to consider below before assuming insulin resistance is the culprit.
Because skin tags can signal prediabetes, PCOS, thyroid or hormonal issues, or nothing serious at all, a free, instant, online symptom check can help you see how your specific combination of symptoms fits together. It takes only a few minutes, requires no sign-up, and gives you a clearer starting point for deciding whether to test, treat, or simply monitor.
Last reviewed for medical accuracy: 09/13
Insulin resistance occurs when your body’s cells don’t respond properly to insulin, the hormone that helps move glucose from your bloodstream into cells for energy. Over time, your pancreas makes more insulin to compensate. This can lead to higher insulin levels in the blood (hyperinsulinemia) and eventually to elevated blood sugar. One visible clue that you may have insulin resistance is the appearance of skin tags—small, soft growths that commonly show up around your neck, underarms or groin.
Skin tags themselves are harmless, but they often signal underlying metabolic changes. If you’ve noticed new or growing skin tags, it’s worth exploring whether insulin resistance may be at play and what you can do to reverse it.
Reversing insulin resistance often involves lifestyle adjustments that improve how your body uses insulin. Below are evidence-based strategies you can start today.
Shifting what—and how—you eat is one of the most powerful ways to improve insulin sensitivity.
Exercise helps your muscles use glucose more efficiently, lowering blood sugar and improving insulin resistance.
Even modest weight loss (5–10% of body weight) can significantly improve insulin sensitivity.
Poor sleep can worsen insulin resistance by disrupting hormonal balance.
Chronic stress raises cortisol, which can increase blood sugar and insulin levels.
Keeping track of your numbers can help you see what’s working and catch any issues early.
If lifestyle changes aren’t enough, medications may help:
If you’re concerned about insulin resistance or related symptoms—such as increasing skin tags, unexplained weight gain, excessive thirst or fatigue—it’s wise to get a full evaluation. You might also consider a free, online symptom check, using the doctor approved Ubie Symptom Checker to gain immediate insights into what might be going on.
Speak to your doctor or a qualified healthcare professional if you experience:
While removing skin tags doesn’t treat insulin resistance, it can boost your comfort and confidence. Always consult a healthcare professional before attempting removal.
Reversing insulin resistance is an ongoing journey, not a one-time fix. Keep these principles in mind:
Insulin resistance is a reversible condition for many people, especially when addressed early. By focusing on a balanced diet, regular exercise, healthy sleep, stress management and medical guidance when needed, you can improve how your body processes insulin—and reduce skin tags along the way.
If you’re unsure where to start or have concerning symptoms, try a free, online symptom check, using the doctor approved Ubie Symptom Checker. And remember: always speak to a doctor about anything that could be life threatening or serious. Your health deserves personalized attention and professional care.
(References)
* Maitra SK, Rowland Payne CM. The obesity syndrome and acanthosis nigricans. Acanthosis nigricans is a common cosmetic problem providing epidemiological clues to the obesity syndrome, the insulin-resistance syndrome, the thrifty metabolism, dyslipidaemia, hypertension and diabetes mellitus type II. J Cosmet Dermatol. 2004 Dec;3(4):202-10. doi: 10.1111/j.1473-2130.2004.00078.x. PMID: 17166107.
* Tamega Ade A, Aranha AM, Guiotoku MM, Miot LD, Miot HA. [Association between skin tags and insulin resistance]. An Bras Dermatol. 2010 Jan-Feb;85(1):25-31. doi: 10.1590/s0365-05962010000100003. PMID: 20464083.
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* Saraiya A, Al-Shoha A, Brodell RT. Hyperinsulinemia associated with acanthosis nigricans, finger pebbles, acrochordons, and the sign of Leser-Trélat. Endocr Pract. 2013 May-Jun;19(3):522-5. doi: 10.4158/EP12192.RA. PMID: 23425641.
* Oran M, Erfan G, Mete R, Yanik ME, Yildirim O, Aydin M, Tasolar K, Topcu B. Association of colon adenomas and skin tags: coincidence or coexistence? Eur Rev Med Pharmacol Sci. 2014;18(7):1073-7. PMID: 24763889.
* Wali V, Wali VV. Assessment of Various Biochemical Parameters and BMI in Patients with Skin Tags. J Clin Diagn Res. 2016 Jan;10(1):BC09-11. doi: 10.7860/JCDR/2016/15994.7062. Epub 2016 Jan 1. PMID: 26894056; PMCID: PMC4740583.
* Agarwal P, Rai P, Jain M, Mishra S, Singh U, Gupta SK. Prevalence of colonic polyp and its predictors in patients with acromegaly. Indian J Endocrinol Metab. 2016 Jul-Aug;20(4):437-42. doi: 10.4103/2230-8210.183455. PMID: 27366708; PMCID: PMC4911831.
* Belgam Syed SY, Lipoff JB, Chatterjee K. Acrochordon. 2026 Jan. PMID: 28846244.
* Uzuncakmak TK, Akdeniz N, Karadag AS. Cutaneous manifestations of obesity and themetabolic syndrome. Clin Dermatol. 2018 Jan-Feb;36(1):81-88. doi: 10.1016/j.clindermatol.2017.09.014. Epub 2017 Sep 8. PMID: 29241757.
* Tripathy T, Singh BSTP, Kar BR. Association of Skin Tag with Metabolic Syndrome and its Components: A Case-control Study from Eastern India. Indian Dermatol Online J. 2019 May-Jun;10(3):284-287. doi: 10.4103/idoj.IDOJ_238_18. PMID: 31149572; PMCID: PMC6536054.
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