Our Services
Medical Information
Helpful Resources
Published on: 2/11/2026
Rick Simpson Oil is a very high THC cannabis extract that may ease pain, sleep problems, nausea, hot flashes, and body aches for some women, but evidence is limited, responses are highly individual, and it should not replace medical care. Next steps include starting low and going slow, checking legality, reviewing medications and hormonal status, watching for side effects like anxiety, dizziness, and impaired driving, avoiding use when pregnant or breastfeeding, and talking with a clinician about fit and interactions. There are several factors to consider; see below for dosing tips, risks, who should and should not use it, and how to choose products and track your response.
Rick Simpson Oil (RSO) is a concentrated cannabis extract that has gained attention for potential symptom relief in women across different life stages. Many women explore RSO to help with pain, sleep problems, mood changes, and other concerns—sometimes alongside conventional care. This guide explains what RSO is, what it may help with, what the science says, and practical next steps—using clear language and credible, evidence‑based context.
Rick Simpson Oil (RSO) is a thick, dark cannabis extract made from the whole cannabis plant. It typically contains very high levels of THC (tetrahydrocannabinol) and smaller amounts of other cannabinoids (like CBD), terpenes, and plant compounds.
Key points to know:
Because of its strength, RSO requires careful dosing and thoughtful consideration—especially for women who may be more sensitive to hormonal and neurological changes.
Women report exploring Rick Simpson Oil (RSO) for a range of symptoms. While individual experiences vary, common reasons include:
It's important to understand that personal stories are not the same as clinical proof. Still, they help explain why interest in RSO has grown.
Research on Rick Simpson Oil (RSO) specifically is limited. However, there is broader scientific research on THC and cannabis‑based medicines that can help inform decisions.
Credible medical organizations generally agree that cannabis products may help with symptom management, but they do not replace evidence‑based medical care.
Women's bodies respond to THC differently at different times of life. Hormonal changes—especially during perimenopause and post‑menopause—can influence how RSO feels and works.
If you're experiencing hot flashes, mood changes, sleep disruption, or other midlife concerns and want to understand whether they're related to hormonal shifts, using a free Peri-/Post-Menopausal Symptoms checker can help you identify patterns and decide on your next steps with more clarity.
RSO is powerful. Understanding risks helps you make informed choices without unnecessary fear.
If you are pregnant, trying to conceive, or breastfeeding, RSO is not recommended due to potential risks to the baby.
Women who choose Rick Simpson Oil (RSO) often use it in very small amounts.
Common approaches include:
Start low and go slow is the most widely accepted harm‑reduction approach. Because potency varies by product, consistency can be challenging.
To avoid confusion and unrealistic expectations, it's important to be clear:
Using RSO without medical guidance—especially for serious or life‑threatening conditions—can delay effective care.
If you're thinking about Rick Simpson Oil (RSO), consider these grounded, practical steps:
Most importantly, speak to a doctor—especially if symptoms are severe, worsening, or could be life‑threatening. This includes chest pain, unexplained weight loss, heavy bleeding, severe depression, or neurological symptoms.
Rick Simpson Oil (RSO) may offer symptom relief for some women, particularly for pain, sleep issues, and certain menopausal complaints. At the same time, it is a high‑THC product with real risks, limited clinical evidence, and significant individual variability.
Used thoughtfully and with medical awareness, RSO may fit into a broader wellness or symptom‑management plan. Used casually or as a substitute for medical care, it can create problems or delay needed treatment.
If you're navigating complex symptoms—especially during peri‑ or post‑menopause—start with understanding your body, consider tools like a free online symptom check, and always involve a healthcare professional in decisions that affect your long‑term health.
(References)
* Armour M, MacIsaac J, Ma C, et al. Cannabinoids for the treatment of endometriosis-associated pain: A systematic review. J Endometr Pelvic Pain Disord. 2023 Apr;15(2):97-106. doi: 10.1177/22840213231163478. Epub 2023 Mar 15. PMID: 37070104.
* O'Brien J, Smith J, Mears M, et al. Real-world evidence on medical cannabis for cancer symptom management in women. Front Pain Res (Lausanne). 2023 Jun 2;4:1196429. doi: 10.3389/fpain.2023.1196429. eCollection 2023. PMID: 37333649.
* Volkow ND, Compton WM, Shokri-Kojori E, et al. The effects of cannabis on the female brain: A review of sex differences in cannabis use disorder and brain function. Neuropsychopharmacology. 2024 Jan;49(1):97-109. doi: 10.1038/s41386-023-01716-4. Epub 2023 Oct 9. PMID: 37813840.
* Bonn-Miller MO, Quigley LB, Bhayani NH, et al. The effects of medical cannabis on cancer-related symptoms and adverse effects: A systematic review and meta-analysis. J Clin Oncol. 2024 Jan 1;42(1):15-27. doi: 10.1200/JCO.23.00331. Epub 2023 Nov 2. PMID: 37910901.
* Boehnke KF, Scott JT, Greenbaum J, et al. Cannabis use for chronic pain: a longitudinal study of patient reported outcomes. J Pain. 2023 Sep;24(9):1605-1616. doi: 10.1016/j.jpain.2023.03.006. Epub 2023 Mar 25. PMID: 36968434.
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.