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Published on: 5/6/2025

What Might Cause Right Lower Abdominal Pain at 6 Weeks Pregnant?

At 6 weeks pregnant, right lower abdominal pain can be caused by several conditions including appendicitis, ovarian cyst complications (such as rupture or torsion), or corpus luteum-related issues. It may also be related to other gastrointestinal or urinary causes.

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Explanation

During early pregnancy (around 6 weeks), several possible conditions can lead to right lower abdominal pain. One important cause to consider is appendicitis, which remains a common source of acute abdominal pain even in pregnant women. The diagnosis can sometimes be challenging because the typical signs may overlap with normal early pregnancy symptoms. Another possibility is that an ovarian cyst—such as a corpus luteum cyst—is causing pain. In early pregnancy, the corpus luteum produces hormones essential for maintaining the pregnancy, but if it becomes overly enlarged, ruptures, or undergoes torsion (twisting), it can cause sudden, sharp pain on one side, often in the right lower area. Other potential causes include gastrointestinal disturbances (like constipation or gas) as well as urinary tract infections, which can also present with lower abdominal pain. Due to the overlap of symptoms and the importance of accurate diagnosis during pregnancy, any significant or persistent pain should be evaluated promptly by a healthcare provider. Investigations may include a physical exam and imaging tests such as ultrasound or, in selected cases, MRI, which are safe during pregnancy. Early evaluation helps ensure the appropriate treatment, protecting both your health and that of your developing baby.

(References)

  • Daume DL, Becker PM, Linke K, Ries JJ, Fourie L, Klasen JM. Differential diagnoses of right lower quadrant pain in late pregnancy. J Surg Case Rep. 2022 Jul 25;2022(7):rjac200. doi: 10.1093/jscr/rjac200. PMID: 35903664; PMCID: PMC9322997.

  • Aptilon Duque G, Oladipo AF, Lotfollahzadeh S. Appendicitis in Pregnancy. [Updated 2023 Nov 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK551642/

  • Zachariah SK, Fenn M, Jacob K, Arthungal SA, Zachariah SA. Management of acute abdomen in pregnancy: current perspectives. Int J Womens Health. 2019 Feb 8;11:119-134. doi: 10.2147/IJWH.S151501. PMID: 30804686; PMCID: PMC6371947.

  • Cappell MS, Friedel D. Abdominal pain during pregnancy. Gastroenterol Clin North Am. 2003 Mar;32(1):1-58. doi: 10.1016/s0889-8553(02)00064-x. PMID: 12635413.

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