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Published on: 8/20/2026
Right-side pain running from your shoulder down to your leg is often caused by nerve, muscle, or spinal issues. Common causes include sciatica (nerve compression in the lower back), scoliosis (curvature of the spine), pinched nerves, muscle strain, or costochondritis (inflammation of the chest wall). In some cases, referred pain from internal organs like the gallbladder or liver can also travel along this path.
Because the symptoms overlap across many conditions—some minor, others serious—self-diagnosis can be risky. The fastest way to understand what's driving your pain and what to do next is to take a free, instant, online symptom check. It only takes a few minutes, is backed by physicians, and gives you personalized insights so you can make an informed decision about next steps.
Reviewed for medical accuracy: 07/15/2026
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When you feel pain on one side from your shoulder all the way down to your leg, there are a few things that might be causing it. One reason is scoliosis, where your spine curves in a twist, which can press on nerves and cause pain along one side. Another possible cause is sciatica. This happens when a nerve in your lower back is squeezed, causing pain to shoot down your leg. Sometimes, the muscles and joints on one side can become sore or inflamed. For example, costochondritis causes pain where your rib bones meet the cartilage near your chest, and this pain can sometimes stretch out to the shoulder and lower body. In some cases, internal issues such as a peptic ulcer (a sore in your stomach lining) may cause pain that you feel on your right side, though this is less common. Because many different things can cause pain along one side of your body, it's important to get personalized insights—you can start by taking a free AI symptom checker assessment to better understand what might be happening and help guide your next steps toward feeling better.
(References)
Goldberg CJ, Moore DP, Fogarty EE, Dowling FE. Scoliosis: a review. Pediatr Surg Int. 2008 Feb;24(2):129-44. doi: 10.1007/s00383-007-2016-5. Epub 2007 Sep 22. PMID: 17891405.
Koes BW, van Tulder MW, Peul WC. Diagnosis and treatment of sciatica. BMJ. 2007 Jun 23;334(7607):1313-7. doi: 10.1136/bmj.39223.428495.BE. PMID: 17585160; PMCID: PMC1895638.
Yamada E, Thomas DC. Common musculoskeletal diagnoses of upper and lower extremities in older patients. Mt Sinai J Med. 2011 Jul-Aug;78(4):546-57. doi: 10.1002/msj.20274. PMID: 21748743.
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