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Published on: 12/10/2025
Rough patches on skin are usually due to common conditions like dry skin, eczema, psoriasis, keratosis pilaris, contact dermatitis, or sun damage (actinic keratosis), but they can also reflect systemic issues such as diabetes, hypothyroidism, nutritional deficiencies, or cholestatic liver disease that causes intense itching. Watch for red flags—rapid change, bleeding, infection, or systemic symptoms (like jaundice)—which warrant medical evaluation. There are several factors to consider; see below for detailed causes, home care versus professional treatments, diagnostic steps, and when to seek care.
What Is Causing the Rough Patch on Your Skin?
Rough patches on the skin are common and usually harmless, but they can be annoying or even painful. Understanding the possible causes can help you decide whether simple home care will do—or if you need to see a doctor. Below is a guide to what might be behind that rough patch on your skin, how it's diagnosed, and when professional help is needed.
Common Causes of Rough Patches on Skin
Systemic and Less Common Causes
Diagnosing a Rough Patch on Skin
A thorough evaluation starts with a skin exam and history:
When necessary, your doctor may order:
Home Care and Over-the-Counter Treatments
For many rough patches, you can start with simple measures:
If you're noticing hard, thickened areas on your skin and aren't sure what's causing them, Ubie's free AI symptom checker can help you identify possible causes and determine if you need medical attention.
Professional Treatments
If home care isn't enough, a healthcare provider may recommend:
When to See a Doctor
Seek medical attention if your rough patch on skin is:
Speak to a doctor promptly about anything that could be life-threatening or serious.
Key Takeaways
Always remember: if you have concerns about your skin—especially changes that are new, worsening or causing significant discomfort—it's best to speak to a doctor.
(References)
Bergasa NV, & Jones EA. (2006). Pathogenesis and treatment of pruritus in cholestatic liver… World J Gastroenterol, 16937426.
Friedrich-Rust M, Ong MF, Martens S, Marotic A, Sarrazin C, Bojunga J, Zeuzem S, & Herrmann E. (2008). Performance of transient elastography for staging of liver… Eur J Gastroenterol Hepatol, 18378833.
European Association for the Study of the Liver. (2017). EASL clinical practice guidelines: management of cholestatic liver… J Hepatol, 29107549.
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