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Published on: 9/15/2026

How much Rick Simpson Oil should I take and how do I use it?

Rick Simpson Oil is a highly concentrated cannabis extract, and typical protocols start with a very small dose about the size of half a grain of rice taken up to three times daily, gradually increased over roughly 90 days, though it can be taken orally, placed under the tongue, or applied to the skin. Because RSO is extremely potent in THC, dosing depends on your tolerance, body weight, other medications, and legal access, and side effects like sedation, dizziness, and anxiety are common when doses rise too quickly. There are several important factors and safety considerations to weigh, so see below to understand more before starting or adjusting a regimen.

If you are considering RSO because of ongoing symptoms, pain, nausea, sleep trouble, or something you cannot quite explain, it helps to know what you may actually be dealing with first. Take a free, instant, online symptom check to get clearer insight into possible causes and practical next steps, including when to talk with a clinician.

Last reviewed for medical accuracy: 09/14/2026

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Explanation

How Much Rick Simpson Oil (RSO) Should I Take and How Do I Use It?

Rick Simpson Oil (RSO) is a concentrated cannabis extract developed by hemp activist Rick Simpson. It’s gained attention for its high cannabinoid content—particularly THC—and its anecdotal use in managing pain, inflammation, and other symptoms. This guide covers general dosing recommendations, administration methods, and important safety notes. Always discuss any serious health concerns with a qualified healthcare provider.


Understanding RSO Dosage

  1. No “One-Size-Fits-All” Dose
    • RSO is extremely potent (often 60–90% THC).
    • Individual response varies based on tolerance, body weight, metabolism, and the condition being addressed.
    • Start low and go slow.

  2. Typical RSO Protocol (Rick Simpson’s Original Recommendation)
    Total Amount: Approx. 60 grams of RSO over ~90 days.
    Daily Intake: ~0.5 gram per day (divided into three or more doses).
    Goal: Complete a full 60-gram course steadily, not all at once.

  3. Micro-Dosing Approach
    For those new to cannabis or seeking milder symptom relief:

    • Start Dose: A “rice grain” size (≈10 mg THC).
    • Frequency: Once or twice daily.
    • Titration: Increase by one additional rice-grain dose every 3–5 days until you reach your desired effect or begin to feel mild intoxication.
  4. Moderate Dosing for Symptom Control

    • Day 1–7: 10 mg THC (rice-grain) once daily.
    • Week 2–3: 10 mg twice daily (20 mg total).
    • Week 4+: 10 mg three times daily (30 mg total), adjusting up to a maximum of 50 mg–60 mg per day if well tolerated and needed.
  5. High-Dose Therapeutic Protocol

    • Often used in anecdotal cancer regimens.
    • Daily Intake: Up to 0.5 gram RSO (300–450 mg THC), divided into three doses (≈0.15 g each).
    • Duration: Continue for 60–90 days, monitoring tolerance and side effects.

How to Use RSO Safely

  1. Oral Administration (Most Common)

    • Syringe/Fingertip Method:
      • RSO often comes in a pre-filled syringe.
      • Place the dose under your tongue for 60–90 seconds before swallowing.
    • With Food:
      • Mix RSO into soft foods (yogurt, applesauce) or spread on crackers.
      • Fatty foods (nut butter, milk) can enhance absorption.
  2. Topical Application

    • For localized pain/inflammation (e.g., arthritis, muscle soreness).
    • Apply a pea-sized amount directly to clean skin; massage gently.
  3. Suppository (Less Common)

    • Some users report better relief for pelvic or lower-back conditions.
    • Requires specialized RSO formulation or preparation in a compounding pharmacy.
  4. Inhalation (Not Typical for RSO)

    • RSO is too viscous and thick for standard vape pens.
    • Not recommended without specialized equipment.

Practical Tips

  • Keep a Journal: Record dose, time, effects, and any side effects.
  • Be Patient: Steady increases over weeks help find your sweet spot without overwhelming side effects.
  • Store Properly: Keep RSO in a cool, dark place (refrigerator works).
  • Label Clearly: Prevent accidental ingestion or dosing by others.

Potential Benefits and Risks

Benefits (Anecdotal/Preliminary Studies)

  • Pain relief
  • Anti-inflammatory effects
  • Appetite stimulation
  • Mood stabilization

Possible Side Effects

  • Drowsiness or sedation
  • Dry mouth
  • Dizziness or lightheadedness
  • Temporary cognitive slowing or mild paranoia (especially at high doses)

Note: Side effects often decrease as tolerance builds. If they persist or become severe, reduce your dose or pause usage.


When to Seek Professional Guidance

  • If you have a serious or life-threatening condition, always speak to a doctor first.
  • For questions about drug interactions (e.g., blood thinners, antidepressants), consult a healthcare professional.
  • Consider a free, online symptom check, using the doctor approved Ubie Symptom Checker to help you decide whether to seek in-person care:
    https://ubiehealth.com/

Final Reminders

  • Start Low, Go Slow: Begin with micro-doses and gradually increase.
  • Individualize Your Plan: Tailor dosage to your goals, tolerance, and response.
  • Monitor Carefully: Keep notes on efficacy and side effects.
  • Consult Your Doctor: Any serious symptoms or concerns should prompt an immediate discussion with a qualified healthcare provider.

By following these guidelines, you can responsibly explore RSO’s potential while minimizing risks. Always prioritize safety, stay informed, and partner with healthcare professionals for the best outcomes.

(References)

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