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Published on: 2/24/2026
Benzonatate numbs cough receptors in the lungs and airways to reduce the urge to cough without affecting breathing, typically starting in 15 to 20 minutes and lasting 3 to 8 hours.
If you are still coughing, there are several factors to consider; see below for medically approved next steps, including when to seek urgent care for red flags like shortness of breath, fever, chest pain, blood in mucus, or a cough over 3 weeks, and targeted options for causes like postnasal drip, GERD, asthma, or infection.
A lingering cough can be frustrating, exhausting, and sometimes concerning. If you've been prescribed benzonatate, you may be wondering how it works, how long it takes to help, and what to do if your cough doesn't improve.
Here's what you need to know—based on credible medical guidance—about benzonatate, when it helps, and what steps to take if you're still coughing.
Benzonatate is a prescription medication used to relieve cough. It is commonly prescribed for coughs caused by:
It is sold under brand names such as Tessalon and Tessalon Perles.
Unlike cough syrups that act on the brain, benzonatate works directly in the lungs and airways. It is classified as a non-narcotic cough suppressant.
Coughing happens when nerve endings in your airways become irritated. These nerves send signals to your brain, triggering the cough reflex.
Benzonatate works by:
This numbing effect helps calm persistent, dry coughing.
It typically starts working within 15 to 20 minutes and can last for 3 to 8 hours.
Proper use is critical.
Chewing or breaking the capsule can cause numbness in the mouth or throat. In rare cases, this may lead to choking or serious reactions.
It reduces symptoms but does not address the underlying cause.
If your cough isn't improving, there are several possible reasons.
Common causes of prolonged cough include:
If you're coughing up mucus, suppressing it too much may not be helpful. Productive coughs help clear the lungs.
In some cases, a persistent cough may signal:
If your symptoms include fever, chest pain, shortness of breath, or worsening fatigue, it's important to look deeper.
To help determine whether your symptoms could indicate something more serious like Pneumonia (Lower Respiratory Tract Infection), you can use a free AI-powered symptom checker that evaluates your specific situation in minutes.
While benzonatate is effective for many people, you should contact a healthcare provider if:
A persistent cough is not always dangerous—but it should not be ignored if it's not improving.
Most people tolerate benzonatate well when taken correctly.
If you experience:
Seek medical care immediately.
Accidental overdose can be dangerous, especially in children. Even a small amount can cause serious harm in young children.
If benzonatate alone isn't enough, your doctor may suggest additional treatments depending on the cause.
Cough duration is generally categorized as:
If your cough moves into the chronic category, a medical evaluation is important. Chronic cough can sometimes signal asthma, chronic bronchitis, or other underlying conditions that need targeted treatment.
Yes. Benzonatate does not cause dependence. You can stop it when:
There is no withdrawal effect.
Speak with a doctor before taking benzonatate if you:
Always follow prescription instructions closely.
While most coughs are caused by viral infections and improve on their own, certain symptoms require prompt medical attention.
Speak to a doctor right away if you have:
These could indicate a serious or life-threatening condition that requires urgent care.
Even if symptoms are mild, consult a healthcare provider if your cough:
It's always better to ask than to guess.
Benzonatate is a safe and effective prescription medication for calming dry, persistent coughs when used correctly. It works by numbing cough receptors in the lungs, helping reduce the urge to cough.
However, it does not treat infections or underlying causes. If your cough continues despite treatment, it may signal something that needs further evaluation.
If you're concerned about whether your lingering cough could be a sign of Pneumonia (Lower Respiratory Tract Infection), a quick online symptom assessment can help clarify your risk and guide your next steps.
And most importantly:
If you experience severe symptoms or anything that feels life-threatening, seek medical care immediately and speak to a doctor. Persistent coughs are common—but they should never be ignored when warning signs are present.
Your lungs matter. Take symptoms seriously, but calmly—and get the right care when you need it.
(References)
* Jain, N., & Gupta, A. (2018). Benzonatate: An Antitussive Agent. In *StatPearls*. StatPearls Publishing.
* Morice, A. H., Millqvist, E., Bieksiene, K., Birring, S. S., Chung, K. F., Diamant, Z., ... & Van Bussel, E. (2018). European Respiratory Society guidelines for the management of chronic cough. *European Respiratory Journal*, *51*(1), 1701349.
* Kahrilas, P. J., & Smith, J. A. (2019). Chronic cough: a practical approach to diagnosis and management. *Clinical and Translational Gastroenterology*, *10*(2), e00010.
* Chung, K. F., & Smith, J. A. (2020). Pathophysiology and management of chronic cough. *The Lancet Respiratory Medicine*, *8*(6), 570-582.
* Polverino, M., Caimmi, S., & Chellini, E. (2022). Therapeutic approaches to chronic cough. *Expert Review of Respiratory Medicine*, *16*(12), 1199-1211.
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