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Published on: 2/28/2026
Sudden fever with chills, sweats, body aches, or fatigue after recent travel or residence in a malaria area can mean your immune system is fighting malaria, a mosquito-borne parasite that invades and bursts red blood cells and causes cyclical fevers.
Act now: get urgent medical care for a malaria blood test such as a blood smear or rapid test and prompt prescription treatment; malaria is serious but highly treatable when diagnosed early, and seek emergency help for red flags like confusion, trouble breathing, seizures, jaundice, severe weakness, or persistent vomiting. There are several factors to consider that can change your next steps, including parasite type, exposure location, and drug resistance; see the complete guidance below to choose the safest plan.
A sudden fever can feel alarming—especially if it comes with chills, sweating, body aches, or fatigue. If you've recently traveled to or live in an area where malaria is common, your immune system may be reacting to a malaria infection.
Understanding what's happening inside your body can help you act quickly and calmly. Malaria is serious—but it is treatable, especially when diagnosed early.
Below, we explain what malaria is, why it causes fever, what symptoms to watch for, and the medically approved next steps you should take.
Malaria is a life-threatening infection caused by parasites (most commonly Plasmodium falciparum or Plasmodium vivax). These parasites are transmitted through the bite of an infected female Anopheles mosquito.
Once inside your body, the parasite:
It's this invasion of your red blood cells that causes most malaria symptoms.
Malaria is most common in:
If you've recently traveled to one of these areas, even weeks ago, malaria should be considered.
Your fever is not random—it's your immune system fighting back.
When malaria parasites infect red blood cells, they multiply inside them. Eventually, the infected cells burst, releasing:
Your immune system recognizes this as a threat and releases chemicals called cytokines. These chemicals:
This cycle can repeat every 48–72 hours, depending on the type of malaria parasite involved. That's why malaria fever can feel intense and come in waves.
Early symptoms often resemble the flu, which is why malaria can sometimes be overlooked.
As the infection progresses, symptoms may worsen.
These are medical emergencies.
Malaria is not just a fever. It directly attacks red blood cells, which carry oxygen throughout your body.
If untreated, malaria can lead to:
Children under 5, pregnant women, older adults, and people with weakened immune systems are at highest risk of severe complications.
This is why early diagnosis and treatment are critical.
If malaria is suspected, a doctor will usually order:
These tests identify the presence of malaria parasites in your bloodstream.
Malaria cannot be diagnosed based on symptoms alone. A laboratory test is required.
If you have a fever and recent travel history, tell your doctor immediately. Travel history is a crucial clue.
The good news: Malaria is treatable with prescription medications.
Treatment depends on:
Common treatments include:
Severe malaria requires:
Do not attempt to self-treat malaria. Proper medication and dosing are essential to prevent complications.
Seek urgent medical attention if you experience:
Malaria can worsen quickly. Acting early significantly improves outcomes.
Because early malaria symptoms resemble flu, COVID-19, or other infections, it can be difficult to know what's causing your fever.
If you're experiencing symptoms and have recently traveled to a malaria-risk area, you can use a free AI-powered Malaria symptom checker to help assess your risk level and understand whether you need urgent medical attention.
A symptom checker is not a diagnosis—but it can help guide whether you should seek urgent care.
Yes.
Depending on the parasite type:
This is why it's important to tell your doctor about travel within the past year, not just recent trips.
If you live in or travel to areas where malaria is common:
For travelers, doctors may prescribe preventive antimalarial medication before, during, and after travel.
Prevention is highly effective when done correctly.
When diagnosed early and treated properly:
Most people recover fully.
The biggest danger comes from delayed diagnosis or untreated infection.
If you have a sudden fever and possible exposure to malaria, do not ignore it.
If you suspect malaria—or if you have a high fever with recent travel history—speak to a doctor immediately.
Malaria can become life-threatening without proper treatment, but it is highly treatable when caught early. A medical professional can perform the necessary blood tests and begin the right therapy.
If symptoms feel severe or rapidly worsening, seek emergency care.
Sudden fever can be frightening, but it is often your body doing exactly what it's designed to do: fight infection. When it comes to malaria, early action makes all the difference.
Listen to your body. Check your symptoms. And when in doubt, speak to a doctor.
(References)
* White NJ, Pukrittayakamee S, Hien TT, Faiz MA, Mokuolu OA, Dondorp AM. Malaria. Lancet. 2014 Mar 29;383(9918):723-35. doi: 10.1016/S0140-6736(13)60024-0. Epub 2013 Nov 1. PMID: 24656124.
* Dondorp AM, Fanello CI, Krishna S, Pukrittayakamee S, Tarning J, White NJ. The Management of Severe Malaria. N Engl J Med. 2019 Jan 10;380(2):189-200. doi: 10.1056/NEJMra1715454. PMID: 30625076.
* Ashley EA, Phyo AP, White NJ. The treatment of uncomplicated malaria. Lancet. 2021 Mar 27;397(10280):1196-1208. doi: 10.1016/S0140-6736(20)32431-3. PMID: 33773121.
* Langhorne J, Ndungu FM, Sponsel N, Nottle L. Immunity to malaria: more questions than answers. Nat Immunol. 2023 Feb;24(2):236-243. doi: 10.1038/s41590-022-01402-w. PMID: 36720743.
* Rosário VE, Lameirão J, Viana M, Arez AP. Recent Advances and Challenges in Malaria Diagnosis. Diagnostics (Basel). 2023 Feb 11;13(4):659. doi: 10.3390/diagnostics13040659. PMID: 36832168; PMCID: PMC9955762.
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