Published on: 3/17/2025
Treating a drool rash from the corners of the mouth usually involves keeping the area clean and dry while using protective creams and, if necessary, targeted medications.
A drool rash at the corners of the mouth often happens when constant moisture irritates the skin. The first step is to gently cleanse the area with mild soap and water, then gently pat it dry. Keeping the affected area dry is important, so consider using a soft tissue or cloth to absorb excess moisture. A protective barrier cream, such as petroleum jelly, can be applied to shield the skin from saliva and prevent further irritation. If the rash appears red, sore, or shows signs of a fungal or bacterial infection, your healthcare provider might recommend topical antifungal or antibiotic treatments. In some cases, if inflammation is significant, a mild topical steroid may be used under supervision; however, these should be used with caution. Additionally, addressing any underlying causes of drooling is important—for instance, if drooling is linked with burning mouth syndrome or other conditions, proper management of those issues can help prevent the rash from recurring. If the irritation persists or worsens, it’s a good idea to speak with a healthcare professional for further evaluation and customized treatment.
(References)
Federico JR, Basehore BM, Zito PM. Angular Chelitis. [Updated 2023 Mar 7]. In: StatPearls [Internet].
Tolaymat L, Hall MR. Perioral Dermatitis. [Updated 2023 Sep 4]. In: StatPearls [Internet].
Bhaiyya PS, Sonar PR, Paul P, Gabhane SS, Rathi A, Dhole PD. Burning Mouth Syndrome in Association With Angular Cheilitis: A Case Report. Cureus. 2024 Aug 21;16(8):e67407. doi: 10.7759/cureus.67407. PMID: 39310405; PMCID: PMC11415152.
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