Drooling From One Side of the Mouth

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Try one of these related symptoms.

Drooling from corner of mouth

Drooling on one side of mouth

Drooling while sleeping

Saliva leaking from corners of mouth

Excessive saliva production

Slight drooling from mouth corners while awake

Drooling sensation on one side of mouth

Dribbling from side of mouth

Drooling from right side of mouth

Drooling from left side of mouth

Drooling while awake

Excess saliva on one side of mouth

About the Symptom

Drooling is when saliva comes out of your mouth. Swallowing problems, muscle control issues, or excessive saliva production can cause drooling. It can also occur during sleep if you sleep with your mouth open.

When to See a Doctor

Seek professional care if you experience any of the following symptoms

Possible Causes

Generally, Drooling from one side of the mouth can be related to:

Related Serious Diseases

Sometimes, Drooling from one side of the mouth may be related to these serious diseases:

Doctor's Diagnostic Questions

Your doctor may ask these questions to check for this symptom:

Reviewed By:

Bret Mobley, MD, MS

Bret Mobley, MD, MS (Neuropathology)

Dr. Mobley graduated from the University of Michigan Medical School, completing a masters degree in neuroscience between his second and third years of medical school. He trained as a resident in pathology at Stanford University Hospital before joining the faculty of Vanderbilt University Medical Center in Nashville Tennessee in 2010. He was promoted to Associate Professor in 2018 and to Neuropathology Division Director in 2020.

Shohei Harase, MD

Shohei Harase, MD (Neurology)

Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.

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Content updated on Jan 29, 2025

Following the Medical Content Editorial Policy

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FAQs

Q.

What Are Effective Methods to Stop Drooling While Sleeping?

A.

To reduce sleeping drooling, you can use a combination of medications, sleep position adjustments, and exercises to help improve saliva control.

References:

James E, Ellis C, Brassington R, Sathasivam S, Young CA. Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis. Cochrane Database Syst Rev. 2022 May 20;5(5):CD006981. doi: 10.1002/14651858.CD006981.pub3. PMID: 35593746; PMCID: PMC9121913.

You P, Strychowsky J, Gandhi K, Chen BA. Anticholinergic treatment for sialorrhea in children: A systematic review. Paediatr Child Health. 2021 Aug 27;27(2):82-87. doi: 10.1093/pch/pxab051. PMID: 35599670; PMCID: PMC9113838.

Thie NM, Kato T, Bader G, Montplaisir JY, Lavigne GJ. The significance of saliva during sleep and the relevance of oromotor movements. Sleep Med Rev. 2002 Jun;6(3):213-27. doi: 10.1053/smrv.2001.0183. PMID: 12531122.

See more on Doctor's Note

Q.

Why Do People Experience Drooling While Sleeping and How Common Is It?

A.

People often drool while sleeping because their mouth muscles relax and they swallow less saliva, and this is generally common.

References:

Thie NM, Kato T, Bader G, Montplaisir JY, Lavigne GJ. The significance of saliva during sleep and the relevance of oromotor movements. Sleep Med Rev. 2002 Jun;6(3):213-27. doi: 10.1053/smrv.2001.0183. PMID: 12531122.

Kalf JG, Bloem BR, Munneke M. Diurnal and nocturnal drooling in Parkinson's disease. J Neurol. 2012 Jan;259(1):119-23. doi: 10.1007/s00415-011-6138-2. Epub 2011 Jun 23. PMID: 21698387; PMCID: PMC3251785.

Chen Y, Huang H, Ning P, Zhao Q, Wang H, Shen Q, Xu Y. Frequency and factors related to drooling in Chinese patients with multiple system atrophy: a cross-sectional study. Clin Auton Res. 2019 Dec;29(6):595-601. doi: 10.1007/s10286-019-00602-2. Epub 2019 Mar 12. PMID: 30864043.

See more on Doctor's Note

Q.

What Are the Common Causes of Excessive Saliva Production?

A.

Excess saliva production (sialorrhea) can be caused by normal body responses, medications, or medical conditions that affect how your mouth and throat work.

References:

Alhajj M, Babos M. Physiology, Salivation. [Updated 2023 Jul 24]. In: StatPearls [Internet].

Boyce HW, Bakheet MR. Sialorrhea: a review of a vexing, often unrecognized sign of oropharyngeal and esophageal disease. J Clin Gastroenterol. 2005 Feb;39(2):89-97. PMID: 15681902.

Iorgulescu G. Saliva between normal and pathological. Important factors in determining systemic and oral health. J Med Life. 2009 Jul-Sep;2(3):303-7. PMID: 20112475; PMCID: PMC5052503.

See more on Doctor's Note

Q.

What Might Cause Sudden Drooling During Sleep?

A.

Sudden drooling during sleep may happen because your mouth’s muscles relax, you swallow less often, or medications increase saliva production.

References:

Freudenreich O. Drug-induced sialorrhea. Drugs Today (Barc). 2005 Jun;41(6):411-8. doi: 10.1358/dot.2005.41.6.893628. PMID: 16110348.

Canfora F, Calabria E, Spagnuolo G, Coppola N, Armogida NG, Mazzaccara C, Solari D, D'Aniello L, Aria M, Pecoraro G, Mignogna MD, Leuci S, Adamo D. Salivary Complaints in Burning Mouth Syndrome: A Cross Sectional Study on 500 Patients. J Clin Med. 2023 Aug 26;12(17):5561. doi: 10.3390/jcm12175561. PMID: 37685630; PMCID: PMC10488611.

Thie NM, Kato T, Bader G, Montplaisir JY, Lavigne GJ. The significance of saliva during sleep and the relevance of oromotor movements. Sleep Med Rev. 2002 Jun;6(3):213-27. doi: 10.1053/smrv.2001.0183. PMID: 12531122.

See more on Doctor's Note

Q.

What Strategies Can Help Stop Drooling While Awake?

A.

Strategies to reduce drooling while awake include exercises and self-management techniques to improve swallowing and muscle control, as well as medications or therapies when needed.

References:

James E, Ellis C, Brassington R, Sathasivam S, Young CA. Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis. Cochrane Database Syst Rev. 2022 May 20;5(5):CD006981. doi: 10.1002/14651858.CD006981.pub3. PMID: 35593746; PMCID: PMC9121913.

de Bruijn TWP, Sohier J, van der Burg JJW. Outpatient Treatment Based on Self-Management Strategies for Chronic Drooling in Two Children. J Dev Phys Disabil. 2017;29(5):735-755. doi: 10.1007/s10882-017-9553-1. Epub 2017 May 31. PMID: 28943744; PMCID: PMC5585278.

Bergmans B, Clark V, Isaacson SH, Bäumer T. Recommendations for a paradigm shift in approach to increase the recognition and treatment of sialorrhea in Parkinson's disease. Clin Park Relat Disord. 2023 Oct 11;9:100223. doi: 10.1016/j.prdoa.2023.100223. Erratum in: Clin Park Relat Disord. 2024 Apr 18;10:100250. doi: 10.1016/j.prdoa.2024.100250. PMID: 38021341; PMCID: PMC10643485.

See more on Doctor's Note

Q.

What Conditions Lead to Excessive Drooling While Sleeping?

A.

Excessive drooling while sleeping can happen when you swallow less during sleep along with conditions that affect muscle control, such as Parkinson’s disease or other neurological issues.

References:

Thie NM, Kato T, Bader G, Montplaisir JY, Lavigne GJ. The significance of saliva during sleep and the relevance of oromotor movements. Sleep Med Rev. 2002 Jun;6(3):213-27. doi: 10.1053/smrv.2001.0183. PMID: 12531122.

Kalf JG, Bloem BR, Munneke M. Diurnal and nocturnal drooling in Parkinson's disease. J Neurol. 2012 Jan;259(1):119-23. doi: 10.1007/s00415-011-6138-2. Epub 2011 Jun 23. PMID: 21698387; PMCID: PMC3251785.

Morgante F, Bavikatte G, Anwar F, Mohamed B. The burden of sialorrhoea in chronic neurological conditions: current treatment options and the role of incobotulinumtoxinA (Xeomin®). Ther Adv Neurol Disord. 2019 Nov 28;12:1756286419888601. doi: 10.1177/1756286419888601. PMID: 31819763; PMCID: PMC6883364.

See more on Doctor's Note

Q.

What Causes Slight Drooling From the Corners of the Mouth While Awake?

A.

Slight drooling from the corners of the mouth while awake can occur when saliva builds up due to decreased swallowing or slight muscle and nerve changes.

References:

Silvestre-Donat FJ, Silvestre-Rangil J. Drooling. Monogr Oral Sci. 2014;24:126-34. doi: 10.1159/000358793. Epub 2014 May 23. PMID: 24862600.

Kalf JG, Bloem BR, Munneke M. Diurnal and nocturnal drooling in Parkinson's disease. J Neurol. 2012 Jan;259(1):119-23. doi: 10.1007/s00415-011-6138-2. Epub 2011 Jun 23. PMID: 21698387; PMCID: PMC3251785.

Lakraj AA, Moghimi N, Jabbari B. Sialorrhea: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins. Toxins (Basel). 2013 May 21;5(5):1010-31. doi: 10.3390/toxins5051010. PMID: 23698357; PMCID: PMC3709276.

See more on Doctor's Note

Q.

What Might Cause a Drooling Sensation on One Side of the Mouth?

A.

Drooling on one side of the mouth can be caused by differences in how your muscles and nerves work on that side, which may lead to extra saliva pooling there.

References:

Canfora F, Calabria E, Spagnuolo G, Coppola N, Armogida NG, Mazzaccara C, Solari D, D'Aniello L, Aria M, Pecoraro G, Mignogna MD, Leuci S, Adamo D. Salivary Complaints in Burning Mouth Syndrome: A Cross Sectional Study on 500 Patients. J Clin Med. 2023 Aug 26;12(17):5561. doi: 10.3390/jcm12175561. PMID: 37685630; PMCID: PMC10488611.

Lakraj AA, Moghimi N, Jabbari B. Sialorrhea: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins. Toxins (Basel). 2013 May 21;5(5):1010-31. doi: 10.3390/toxins5051010. PMID: 23698357; PMCID: PMC3709276.

Meningaud JP, Pitak-Arnnop P, Chikhani L, Bertrand JC. Drooling of saliva: a review of the etiology and management options. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Jan;101(1):48-57. doi: 10.1016/j.tripleo.2005.08.018. PMID: 16360607.

See more on Doctor's Note

Q.

Is There a Connection between Sweating and Drooling While Sleeping?

A.

Yes, there can be a connection between sweating and drooling during sleep because both are controlled by your body's autonomic system.

References:

Pearlmutter P, DeRose G, Samson C, Linehan N, Cen Y, Begdache L, Won D, Koh A. Sweat and saliva cortisol response to stress and nutrition factors. Sci Rep. 2020 Nov 4;10(1):19050. doi: 10.1038/s41598-020-75871-3. PMID: 33149196; PMCID: PMC7643128.

Thie NM, Kato T, Bader G, Montplaisir JY, Lavigne GJ. The significance of saliva during sleep and the relevance of oromotor movements. Sleep Med Rev. 2002 Jun;6(3):213-27. doi: 10.1053/smrv.2001.0183. PMID: 12531122.

Kalf JG, Bloem BR, Munneke M. Diurnal and nocturnal drooling in Parkinson's disease. J Neurol. 2012 Jan;259(1):119-23. doi: 10.1007/s00415-011-6138-2. Epub 2011 Jun 23. PMID: 21698387; PMCID: PMC3251785.

See more on Doctor's Note

Q.

How Can a Drool Rash at the Corner of the Mouth Be Treated?

A.

Treating a drool rash from the corners of the mouth usually involves keeping the area clean and dry while using protective creams and, if necessary, targeted medications.

References:

Federico JR, Basehore BM, Zito PM. Angular Chelitis. [Updated 2023 Mar 7]. In: StatPearls [Internet].

Tolaymat L, Hall MR. Perioral Dermatitis. [Updated 2023 Sep 4]. In: StatPearls [Internet].

Bhaiyya PS, Sonar PR, Paul P, Gabhane SS, Rathi A, Dhole PD. Burning Mouth Syndrome in Association With Angular Cheilitis: A Case Report. Cureus. 2024 Aug 21;16(8):e67407. doi: 10.7759/cureus.67407. PMID: 39310405; PMCID: PMC11415152.

See more on Doctor's Note

Q.

Why Am I Producing So Much Saliva All of a Sudden?

A.

Sudden, excessive saliva production can result from changes in your body, medications, or even stress and hunger cues.

References:

Iorgulescu G. Saliva between normal and pathological. Important factors in determining systemic and oral health. J Med Life. 2009 Jul-Sep;2(3):303-7. PMID: 20112475; PMCID: PMC5052503.

Jansen A, Boon B, Nauta H, van den Hout M. Salivation discordant with hunger. Behav Res Ther. 1992 Mar;30(2):163-6. doi: 10.1016/0005-7967(92)90139-8. PMID: 1567345.

Miranda-Rius J, Brunet-Llobet L, Lahor-Soler E, Farré M. Salivary Secretory Disorders, Inducing Drugs, and Clinical Management. Int J Med Sci. 2015 Sep 22;12(10):811-24. doi: 10.7150/ijms.12912. PMID: 26516310; PMCID: PMC4615242.

See more on Doctor's Note

Q.

What Does It Mean If You Are Producing a Lot of Saliva?

A.

Producing a lot of saliva can be a normal reaction or sometimes a sign that your body is trying to protect or clean your mouth, but in some cases, it might indicate an underlying issue.

References:

Iorgulescu G. Saliva between normal and pathological. Important factors in determining systemic and oral health. J Med Life. 2009 Jul-Sep;2(3):303-7. PMID: 20112475; PMCID: PMC5052503.

Bozorgi C, Holleufer C, Wendin K. Saliva Secretion and Swallowing-The Impact of Different Types of Food and Drink on Subsequent Intake. Nutrients. 2020 Jan 19;12(1):256. doi: 10.3390/nu12010256. PMID: 31963804; PMCID: PMC7019672.

Thie NM, Kato T, Bader G, Montplaisir JY, Lavigne GJ. The significance of saliva during sleep and the relevance of oromotor movements. Sleep Med Rev. 2002 Jun;6(3):213-27. doi: 10.1053/smrv.2001.0183. PMID: 12531122.

See more on Doctor's Note

Q.

What Causes Drooling on One Side of the Mouth?

A.

Drooling on one side of the mouth can result from uneven muscle or nerve control, side-specific gland activity, or the impact of certain medications on saliva production.

References:

Lakraj AA, Moghimi N, Jabbari B. Sialorrhea: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins. Toxins (Basel). 2013 May 21;5(5):1010-31. doi: 10.3390/toxins5051010. PMID: 23698357; PMCID: PMC3709276.

Meningaud JP, Pitak-Arnnop P, Chikhani L, Bertrand JC. Drooling of saliva: a review of the etiology and management options. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Jan;101(1):48-57. doi: 10.1016/j.tripleo.2005.08.018. PMID: 16360607.

Miranda-Rius J, Brunet-Llobet L, Lahor-Soler E, Farré M. Salivary Secretory Disorders, Inducing Drugs, and Clinical Management. Int J Med Sci. 2015 Sep 22;12(10):811-24. doi: 10.7150/ijms.12912. PMID: 26516310; PMCID: PMC4615242.

See more on Doctor's Note

Q.

Why Is Saliva Leaking From the Corners of My Mouth?

A.

Saliva leaking from the corners of your mouth can happen when your body makes too much saliva or when you don’t swallow it regularly, often due to muscle control or nerve issues.

References:

Lakraj AA, Moghimi N, Jabbari B. Sialorrhea: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins. Toxins (Basel). 2013 May 21;5(5):1010-31. doi: 10.3390/toxins5051010. PMID: 23698357; PMCID: PMC3709276.

Meningaud JP, Pitak-Arnnop P, Chikhani L, Bertrand JC. Drooling of saliva: a review of the etiology and management options. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Jan;101(1):48-57. doi: 10.1016/j.tripleo.2005.08.018. PMID: 16360607.

Błochowiak K, Olewicz-Gawlik A, Polańska A, Nowak-Gabryel M, Kocięcki J, Witmanowski H, Sokalski J. Oral mucosal manifestations in primary and secondary Sjögren syndrome and dry mouth syndrome. Postepy Dermatol Alergol. 2016 Feb;33(1):23-7. doi: 10.5114/pdia.2016.57764. Epub 2016 Feb 29. PMID: 26985175; PMCID: PMC4793060.

See more on Doctor's Note

Q.

What Are the Reasons for Drooling While Awake?

A.

Drooling while awake can happen when the body produces extra saliva or when swallowing isn’t working well, often due to neurological problems or side effects from medications.

References:

Polychronis S, Nasios G, Dardiotis E, Messinis L, Pagano G. Pathophysiology and Symptomatology of Drooling in Parkinson's Disease. Healthcare (Basel). 2022 Mar 11;10(3):516. doi: 10.3390/healthcare10030516. PMID: 35326994; PMCID: PMC8951596.

Silvestre-Donat FJ, Silvestre-Rangil J. Drooling. Monogr Oral Sci. 2014;24:126-34. doi: 10.1159/000358793. Epub 2014 May 23. PMID: 24862600.

Freudenreich O. Drug-induced sialorrhea. Drugs Today (Barc). 2005 Jun;41(6):411-8. doi: 10.1358/dot.2005.41.6.893628. PMID: 16110348.

See more on Doctor's Note

Q.

What Causes Drooling From the Corners of My Mouth?

A.

Drooling from the corners of your mouth can happen when extra saliva builds up and isn’t swallowed, often because of conditions like burning mouth syndrome or side effects from medications.

References:

Canfora F, Calabria E, Spagnuolo G, Coppola N, Armogida NG, Mazzaccara C, Solari D, D'Aniello L, Aria M, Pecoraro G, Mignogna MD, Leuci S, Adamo D. Salivary Complaints in Burning Mouth Syndrome: A Cross Sectional Study on 500 Patients. J Clin Med. 2023 Aug 26;12(17):5561. doi: 10.3390/jcm12175561. PMID: 37685630; PMCID: PMC10488611.

Silvestre-Donat FJ, Silvestre-Rangil J. Drooling. Monogr Oral Sci. 2014;24:126-34. doi: 10.1159/000358793. Epub 2014 May 23. PMID: 24862600.

Freudenreich O. Drug-induced sialorrhea. Drugs Today (Barc). 2005 Jun;41(6):411-8. doi: 10.1358/dot.2005.41.6.893628. PMID: 16110348.

See more on Doctor's Note

Q.

What Are the Medical Conditions Associated with Excessive Production of Saliva?

A.

Excessive saliva, or sialorrhea, can be associated with several medical conditions that affect the mouth, throat, or nervous system.

References:

Alhajj M, Babos M. Physiology, Salivation. [Updated 2023 Jul 24]. In: StatPearls [Internet].

Boyce HW, Bakheet MR. Sialorrhea: a review of a vexing, often unrecognized sign of oropharyngeal and esophageal disease. J Clin Gastroenterol. 2005 Feb;39(2):89-97. PMID: 15681902.

Lakraj AA, Moghimi N, Jabbari B. Sialorrhea: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins. Toxins (Basel). 2013 May 21;5(5):1010-31. doi: 10.3390/toxins5051010. PMID: 23698357; PMCID: PMC3709276.

See more on Doctor's Note

Q.

Why Is My Mouth Suddenly Full of Saliva?

A.

A sudden increase in saliva can happen when your mouth makes extra saliva or you’re not swallowing as often, which can be caused by reasons like burning mouth syndrome, certain foods, or even changes in your body.

References:

Canfora F, Calabria E, Spagnuolo G, Coppola N, Armogida NG, Mazzaccara C, Solari D, D'Aniello L, Aria M, Pecoraro G, Mignogna MD, Leuci S, Adamo D. Salivary Complaints in Burning Mouth Syndrome: A Cross Sectional Study on 500 Patients. J Clin Med. 2023 Aug 26;12(17):5561. doi: 10.3390/jcm12175561. PMID: 37685630; PMCID: PMC10488611.

Alhajj M, Babos M. Physiology, Salivation. [Updated 2023 Jul 24]. In: StatPearls [Internet].

Bozorgi C, Holleufer C, Wendin K. Saliva Secretion and Swallowing-The Impact of Different Types of Food and Drink on Subsequent Intake. Nutrients. 2020 Jan 19;12(1):256. doi: 10.3390/nu12010256. PMID: 31963804; PMCID: PMC7019672.

See more on Doctor's Note

Q.

What Could Cause Drooling From the Left Side of the Mouth?

A.

Drooling from one side of the mouth can happen when the muscles or nerves controlling saliva aren’t working evenly, which may be due to medication side effects or a neurological condition such as Parkinson’s disease.

References:

Freudenreich O. Drug-induced sialorrhea. Drugs Today (Barc). 2005 Jun;41(6):411-8. doi: 10.1358/dot.2005.41.6.893628. PMID: 16110348.

Leung AK, Kao CP. Drooling in children. Paediatr Child Health. 1999 Sep;4(6):406-11. doi: 10.1093/pch/4.6.406. PMID: 20212951; PMCID: PMC2827743.

Polychronis S, Nasios G, Dardiotis E, Messinis L, Pagano G. Pathophysiology and Symptomatology of Drooling in Parkinson's Disease. Healthcare (Basel). 2022 Mar 11;10(3):516. doi: 10.3390/healthcare10030516. PMID: 35326994; PMCID: PMC8951596.

See more on Doctor's Note

Q.

What Does White Saliva at the Corner of the Mouth Indicate?

A.

White saliva at the corner of your mouth may indicate that the saliva is becoming thicker or drying out, which can be a sign of irritation or even a yeast infection like Candida that can lead to angular cheilitis.

References:

Federico JR, Basehore BM, Zito PM. Angular Chelitis. [Updated 2023 Mar 7]. In: StatPearls [Internet].

Taylor M, Brizuela M, Raja A. Oral Candidiasis. [Updated 2023 Jul 4]. In: StatPearls [Internet].

Proctor GB, Shaalan AM. Disease-Induced Changes in Salivary Gland Function and the Composition of Saliva. J Dent Res. 2021 Oct;100(11):1201-1209. doi: 10.1177/00220345211004842. Epub 2021 Apr 17. PMID: 33870742; PMCID: PMC8461045.

See more on Doctor's Note

Q.

What Could Cause Drooling on the Right Side of the Mouth?

A.

Drooling on one side of your mouth can happen when the nerves or muscles on that side are not working as well as the other side, making it hard to swallow saliva evenly.

References:

Morgante F, Bavikatte G, Anwar F, Mohamed B. The burden of sialorrhoea in chronic neurological conditions: current treatment options and the role of incobotulinumtoxinA (Xeomin®). Ther Adv Neurol Disord. 2019 Nov 28;12:1756286419888601. doi: 10.1177/1756286419888601. PMID: 31819763; PMCID: PMC6883364.

Schubert G, Haverland J, Wyst CV, McGreevy J. How Much Drool Is Too Much? Clin Pediatr Emerg Med. 2019 Dec;20(4):100742. doi: 10.1016/j.cpem.2019.100742. Epub 2019 Dec 13. PMID: 32288647; PMCID: PMC7106023.

Iorgulescu G. Saliva between normal and pathological. Important factors in determining systemic and oral health. J Med Life. 2009 Jul-Sep;2(3):303-7. PMID: 20112475; PMCID: PMC5052503.

See more on Doctor's Note

Q.

Can Medication Cause Drooling As a Side Effect?

A.

Yes, some medications can lead to drooling because they affect your saliva production and how well you swallow.

References:

Essali A, Rihawi A, Altujjar M, Alhafez B, Tarboush A, Alhaj Hasan N. Anticholinergic medication for non-clozapine neuroleptic-induced hypersalivation in people with schizophrenia. Cochrane Database Syst Rev. 2013 Dec 19;2013(12):CD009546. doi: 10.1002/14651858.CD009546.pub2. PMID: 24353163; PMCID: PMC11357688.

Miranda-Rius J, Brunet-Llobet L, Lahor-Soler E, Farré M. Salivary Secretory Disorders, Inducing Drugs, and Clinical Management. Int J Med Sci. 2015 Sep 22;12(10):811-24. doi: 10.7150/ijms.12912. PMID: 26516310; PMCID: PMC4615242.

Wolff A, Joshi RK, Ekström J, Aframian D, Pedersen AM, Proctor G, Narayana N, Villa A, Sia YW, Aliko A, McGowan R, Kerr AR, Jensen SB, Vissink A, Dawes C. A Guide to Medications Inducing Salivary Gland Dysfunction, Xerostomia, and Subjective Sialorrhea: A Systematic Review Sponsored by the World Workshop on Oral Medicine VI. Drugs R D. 2017 Mar;17(1):1-28. doi: 10.1007/s40268-016-0153-9. PMID: 27853957; PMCID: PMC5318321.

See more on Doctor's Note

Q.

What Causes Saliva to Build Up in the Corner of My Mouth?

A.

Saliva can build up in the corner of your mouth when the normal swallowing process is reduced or if your mouth muscles and nerves aren’t fully controlling the saliva flow.

References:

Morgante F, Bavikatte G, Anwar F, Mohamed B. The burden of sialorrhoea in chronic neurological conditions: current treatment options and the role of incobotulinumtoxinA (Xeomin®). Ther Adv Neurol Disord. 2019 Nov 28;12:1756286419888601. doi: 10.1177/1756286419888601. PMID: 31819763; PMCID: PMC6883364.

Bhaiyya PS, Sonar PR, Paul P, Gabhane SS, Rathi A, Dhole PD. Burning Mouth Syndrome in Association With Angular Cheilitis: A Case Report. Cureus. 2024 Aug 21;16(8):e67407. doi: 10.7759/cureus.67407. PMID: 39310405; PMCID: PMC11415152.

See more on Doctor's Note

Q.

Why Does Saliva Collect in the Corner of My Mouth When Talking?

A.

When you talk, you may notice saliva collecting at the corners of your mouth because you're swallowing less frequently and the natural movement of your lips can allow saliva to pool.

References:

Canfora F, Calabria E, Spagnuolo G, Coppola N, Armogida NG, Mazzaccara C, Solari D, D'Aniello L, Aria M, Pecoraro G, Mignogna MD, Leuci S, Adamo D. Salivary Complaints in Burning Mouth Syndrome: A Cross Sectional Study on 500 Patients. J Clin Med. 2023 Aug 26;12(17):5561. doi: 10.3390/jcm12175561. PMID: 37685630; PMCID: PMC10488611.

Iorgulescu G. Saliva between normal and pathological. Important factors in determining systemic and oral health. J Med Life. 2009 Jul-Sep;2(3):303-7. PMID: 20112475; PMCID: PMC5052503.

Satzl M, Schmierer A, Zeman F, Schmalz G, Loew T. Significant variation in salivation by short-term suggestive intervention: a randomized controlled cross-over clinical study. Head Face Med. 2014 Nov 27;10:49. doi: 10.1186/1746-160X-10-49. PMID: 25428655; PMCID: PMC4289223.

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Q.

Can Drooling Lead to Angular Cheilitis?

A.

Yes, drooling can lead to angular cheilitis because constant moisture can irritate and break down the skin at the corners of the mouth.

References:

Bhaiyya PS, Sonar PR, Paul P, Gabhane SS, Rathi A, Dhole PD. Burning Mouth Syndrome in Association With Angular Cheilitis: A Case Report. Cureus. 2024 Aug 21;16(8):e67407. doi: 10.7759/cureus.67407. PMID: 39310405; PMCID: PMC11415152.

Lugović-Mihić L, Pilipović K, Crnarić I, Šitum M, Duvančić T. Differential Diagnosis of Cheilitis - How to Classify Cheilitis? Acta Clin Croat. 2018 Jun;57(2):342-351. doi: 10.20471/acc.2018.57.02.16. PMID: 30431729; PMCID: PMC6531998.

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Q.

What Might Cause Slight Drooling From the Right Side of the Mouth?

A.

Slight drooling from one side of the mouth can occur when the nerves or muscles on that side do not manage saliva as well as on the other side, which may happen in early or mild neurological disorders.

References:

Polychronis S, Nasios G, Dardiotis E, Messinis L, Pagano G. Pathophysiology and Symptomatology of Drooling in Parkinson's Disease. Healthcare (Basel). 2022 Mar 11;10(3):516. doi: 10.3390/healthcare10030516. PMID: 35326994; PMCID: PMC8951596.

Iorgulescu G. Saliva between normal and pathological. Important factors in determining systemic and oral health. J Med Life. 2009 Jul-Sep;2(3):303-7. PMID: 20112475; PMCID: PMC5052503.

Huang T, Tang LL, Zhao JY, Shang SA, Chen YC, Tian YY, Zhang YD. Drooling disrupts the brain functional connectivity network in Parkinson's disease. CNS Neurosci Ther. 2023 Oct;29(10):3094-3107. doi: 10.1111/cns.14251. Epub 2023 May 5. PMID: 37144606; PMCID: PMC10493659.

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Q.

What Causes a Sensation of Drooling on the Left Side of the Mouth?

A.

A drooling sensation on one side of your mouth may happen when the nerves or muscles on that side do not manage saliva as well as the other side, sometimes due to neurological conditions like Parkinson’s disease.

References:

Polychronis S, Nasios G, Dardiotis E, Messinis L, Pagano G. Pathophysiology and Symptomatology of Drooling in Parkinson's Disease. Healthcare (Basel). 2022 Mar 11;10(3):516. doi: 10.3390/healthcare10030516. PMID: 35326994; PMCID: PMC8951596.

Iorgulescu G. Saliva between normal and pathological. Important factors in determining systemic and oral health. J Med Life. 2009 Jul-Sep;2(3):303-7. PMID: 20112475; PMCID: PMC5052503.

Huang T, Tang LL, Zhao JY, Shang SA, Chen YC, Tian YY, Zhang YD. Drooling disrupts the brain functional connectivity network in Parkinson's disease. CNS Neurosci Ther. 2023 Oct;29(10):3094-3107. doi: 10.1111/cns.14251. Epub 2023 May 5. PMID: 37144606; PMCID: PMC10493659.

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Q.

What Might Cause Excess Saliva on One Side of the Mouth?

A.

Excess saliva on one side of the mouth can happen when one salivary gland or its control system acts differently than the other, causing more saliva to be produced or not cleared well.

References:

Miranda-Rius J, Brunet-Llobet L, Lahor-Soler E, Farré M. Salivary Secretory Disorders, Inducing Drugs, and Clinical Management. Int J Med Sci. 2015 Sep 22;12(10):811-24. doi: 10.7150/ijms.12912. PMID: 26516310; PMCID: PMC4615242.

Bozorgi C, Holleufer C, Wendin K. Saliva Secretion and Swallowing-The Impact of Different Types of Food and Drink on Subsequent Intake. Nutrients. 2020 Jan 19;12(1):256. doi: 10.3390/nu12010256. PMID: 31963804; PMCID: PMC7019672.

Iorgulescu G. Saliva between normal and pathological. Important factors in determining systemic and oral health. J Med Life. 2009 Jul-Sep;2(3):303-7. PMID: 20112475; PMCID: PMC5052503.

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Q.

What Causes a Sensation of Drooling on the Right Side of the Mouth?

A.

A feeling of drooling on one side of your mouth may be caused by uneven saliva control due to nerve or muscle issues that affect one side more than the other.

References:

Lakraj AA, Moghimi N, Jabbari B. Sialorrhea: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins. Toxins (Basel). 2013 May 21;5(5):1010-31. doi: 10.3390/toxins5051010. PMID: 23698357; PMCID: PMC3709276.

Morgante F, Bavikatte G, Anwar F, Mohamed B. The burden of sialorrhoea in chronic neurological conditions: current treatment options and the role of incobotulinumtoxinA (Xeomin®). Ther Adv Neurol Disord. 2019 Nov 28;12:1756286419888601. doi: 10.1177/1756286419888601. PMID: 31819763; PMCID: PMC6883364.

Srivanitchapoom P, Pandey S, Hallett M. Drooling in Parkinson's disease: a review. Parkinsonism Relat Disord. 2014 Nov;20(11):1109-18. doi: 10.1016/j.parkreldis.2014.08.013. Epub 2014 Aug 27. PMID: 25200111; PMCID: PMC4252747.

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Q.

What Could Cause Saliva to Drip From the Side of the Mouth?

A.

Saliva dripping from the side of your mouth can happen when too much saliva is made or when you have trouble swallowing it, which is often seen with certain nerve or muscle problems.

References:

Lakraj AA, Moghimi N, Jabbari B. Sialorrhea: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins. Toxins (Basel). 2013 May 21;5(5):1010-31. doi: 10.3390/toxins5051010. PMID: 23698357; PMCID: PMC3709276.

Morgante F, Bavikatte G, Anwar F, Mohamed B. The burden of sialorrhoea in chronic neurological conditions: current treatment options and the role of incobotulinumtoxinA (Xeomin®). Ther Adv Neurol Disord. 2019 Nov 28;12:1756286419888601. doi: 10.1177/1756286419888601. PMID: 31819763; PMCID: PMC6883364.

Srivanitchapoom P, Pandey S, Hallett M. Drooling in Parkinson's disease: a review. Parkinsonism Relat Disord. 2014 Nov;20(11):1109-18. doi: 10.1016/j.parkreldis.2014.08.013. Epub 2014 Aug 27. PMID: 25200111; PMCID: PMC4252747.

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Q.

What Conditions Might Excess Saliva Be a Symptom Of?

A.

Excess saliva can be a sign of conditions that affect the nerves, mouth, or salivary glands, like certain neurological diseases or burning mouth syndrome.

References:

Morgante F, Bavikatte G, Anwar F, Mohamed B. The burden of sialorrhoea in chronic neurological conditions: current treatment options and the role of incobotulinumtoxinA (Xeomin®). Ther Adv Neurol Disord. 2019 Nov 28;12:1756286419888601. doi: 10.1177/1756286419888601. PMID: 31819763; PMCID: PMC6883364.

Canfora F, Calabria E, Spagnuolo G, Coppola N, Armogida NG, Mazzaccara C, Solari D, D'Aniello L, Aria M, Pecoraro G, Mignogna MD, Leuci S, Adamo D. Salivary Complaints in Burning Mouth Syndrome: A Cross Sectional Study on 500 Patients. J Clin Med. 2023 Aug 26;12(17):5561. doi: 10.3390/jcm12175561. PMID: 37685630; PMCID: PMC10488611.

Proctor GB, Shaalan AM. Disease-Induced Changes in Salivary Gland Function and the Composition of Saliva. J Dent Res. 2021 Oct;100(11):1201-1209. doi: 10.1177/00220345211004842. Epub 2021 Apr 17. PMID: 33870742; PMCID: PMC8461045.

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Q.

How Can I Get Rid of Excess Saliva in My Mouth?

A.

You can reduce excess saliva by using certain medications or treatments, like anticholinergic drugs or botulinum toxin injections, under a doctor's guidance.

References:

MohammadSadeghi A, Karimzadeh I, Bagheri Lankarani K, Banakar M. Pharmacotherapy for reducing saliva and droplet production in airborne procedures may help to decrease the COVID-19 transmission: A hypothesis. Med Hypotheses. 2020 Nov;144:109874. doi: 10.1016/j.mehy.2020.109874. Epub 2020 Jun 1. PMID: 32535455; PMCID: PMC7831535.

Lakraj AA, Moghimi N, Jabbari B. Sialorrhea: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins. Toxins (Basel). 2013 May 21;5(5):1010-31. doi: 10.3390/toxins5051010. PMID: 23698357; PMCID: PMC3709276.

James E, Ellis C, Brassington R, Sathasivam S, Young CA. Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis. Cochrane Database Syst Rev. 2022 May 20;5(5):CD006981. doi: 10.1002/14651858.CD006981.pub3. PMID: 35593746; PMCID: PMC9121913.

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Q.

What Could Cause Salty Saliva on One Side of the Mouth?

A.

Salty saliva on one side of your mouth might be due to a change in how your salivary glands work, which could be influenced by an infection, medication, or other local factors.

References:

Abduljabbar T, Alhamdan RS, Al Deeb M, AlAali KA, Vohra F. Association of Salivary Content Alteration and Early Ageusia Symptoms in COVID-19 Infections: A Systematic Review. Eur J Dent. 2020 Dec;14(S 01):S152-S158. doi: 10.1055/s-0040-1716986. Epub 2020 Nov 26. PMID: 33242917; PMCID: PMC7775251.

Miranda-Rius J, Brunet-Llobet L, Lahor-Soler E, Farré M. Salivary Secretory Disorders, Inducing Drugs, and Clinical Management. Int J Med Sci. 2015 Sep 22;12(10):811-24. doi: 10.7150/ijms.12912. PMID: 26516310; PMCID: PMC4615242.

Zolotukhin S. Metabolic hormones in saliva: origins and functions. Oral Dis. 2013 Apr;19(3):219-29. doi: 10.1111/odi.12015. Epub 2012 Sep 21. PMID: 22994880; PMCID: PMC3530011.

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Q.

How Can I Stop the Corners of My Mouth From Drooling?

A.

You can help stop drooling from the corners of your mouth by reducing saliva production or helping your muscles control it better, using treatments like botulinum toxin injections or certain medications.

References:

Lakraj AA, Moghimi N, Jabbari B. Sialorrhea: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins. Toxins (Basel). 2013 May 21;5(5):1010-31. doi: 10.3390/toxins5051010. PMID: 23698357; PMCID: PMC3709276.

Chen CR, Su YC, Chen HC, Lin YC. Botulinum Toxin for Drooling in Adults with Diseases of the Central Nervous System: A Meta-Analysis. Healthcare (Basel). 2023 Jul 6;11(13):1956. doi: 10.3390/healthcare11131956. PMID: 37444790; PMCID: PMC10341342.

Bittmann S, Luchter E, Bittmann L, Moschuring-Alieva E, Villalon G. Current Aspects of Treatment Options of Chronic Sialorrhea in Children. J Clin Med Res. 2022 Jun;14(6):246-249. doi: 10.14740/jocmr4766. Epub 2022 Jun 27. PMID: 35836725; PMCID: PMC9275433.

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Q.

What Causes the Corner of the Mouth to Feel Like It's Drooling?

A.

The feeling of drooling at the corner of your mouth may be caused by conditions that increase saliva production or affect how you control saliva, such as burning mouth syndrome or neurological conditions like Parkinson’s disease.

References:

Canfora F, Calabria E, Spagnuolo G, Coppola N, Armogida NG, Mazzaccara C, Solari D, D'Aniello L, Aria M, Pecoraro G, Mignogna MD, Leuci S, Adamo D. Salivary Complaints in Burning Mouth Syndrome: A Cross Sectional Study on 500 Patients. J Clin Med. 2023 Aug 26;12(17):5561. doi: 10.3390/jcm12175561. PMID: 37685630; PMCID: PMC10488611.

https://www.medsci.org/v12p0811.htm

https://www.medsci.org/v12p0811.htm

Polychronis S, Nasios G, Dardiotis E, Messinis L, Pagano G. Pathophysiology and Symptomatology of Drooling in Parkinson's Disease. Healthcare (Basel). 2022 Mar 11;10(3):516. doi: 10.3390/healthcare10030516. PMID: 35326994; PMCID: PMC8951596.

See more on Doctor's Note

Q.

What Might Cause Excess Saliva on the Right Side of the Mouth?

A.

Excess saliva on one side of your mouth might be linked to a local issue with the salivary glands or differences in how nerves and muscles manage saliva on that side.

References:

Miranda-Rius J, Brunet-Llobet L, Lahor-Soler E, Farré M. Salivary Secretory Disorders, Inducing Drugs, and Clinical Management. Int J Med Sci. 2015 Sep 22;12(10):811-24. doi: 10.7150/ijms.12912. PMID: 26516310; PMCID: PMC4615242.

Lakraj AA, Moghimi N, Jabbari B. Sialorrhea: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins. Toxins (Basel). 2013 May 21;5(5):1010-31. doi: 10.3390/toxins5051010. PMID: 23698357; PMCID: PMC3709276.

Leung AK, Kao CP. Drooling in children. Paediatr Child Health. 1999 Sep;4(6):406-11. doi: 10.1093/pch/4.6.406. PMID: 20212951; PMCID: PMC2827743.

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Q.

What Could Cause More Saliva on One Side of the Mouth?

A.

More saliva on one side of the mouth can happen when one salivary gland is working differently or when the nerves and muscles on that side do not control saliva as well.

References:

Lakraj AA, Moghimi N, Jabbari B. Sialorrhea: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins. Toxins (Basel). 2013 May 21;5(5):1010-31. doi: 10.3390/toxins5051010. PMID: 23698357; PMCID: PMC3709276.

Miranda-Rius J, Brunet-Llobet L, Lahor-Soler E, Farré M. Salivary Secretory Disorders, Inducing Drugs, and Clinical Management. Int J Med Sci. 2015 Sep 22;12(10):811-24. doi: 10.7150/ijms.12912. PMID: 26516310; PMCID: PMC4615242.

Iorgulescu G. Saliva between normal and pathological. Important factors in determining systemic and oral health. J Med Life. 2009 Jul-Sep;2(3):303-7. PMID: 20112475; PMCID: PMC5052503.

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