Our Services
Medical Information
Helpful Resources
Published on: 9/23/2026
Low HDL cholesterol means your "good" cholesterol, which helps clear excess cholesterol from your arteries, is under about 40 mg/dL for men or 50 mg/dL for women, which raises the risk of plaque buildup, heart attack, and stroke. Common causes include inactivity, smoking, excess weight, insulin resistance, a diet high in refined carbs and trans fats, certain medications, and inherited factors. Raising it usually involves regular aerobic exercise, quitting smoking, losing extra weight, replacing trans and refined carbs with healthy fats like olive oil, nuts, and fatty fish, and moderating alcohol. Because HDL is only one piece of your cardiovascular picture, and because triglycerides, LDL, and underlying conditions change what your numbers actually mean, there are several important factors to consider before acting on a single result. See below to understand more.
If you are unsure whether your cholesterol numbers, fatigue, or other symptoms point to a larger metabolic or heart issue, a few minutes of clarity can help you decide what to do next and what to ask your doctor. Take a free, instant, online symptom check to better understand what may be going on and how to navigate your next steps.
Last reviewed for medical accuracy: 09/23/2026
High-density lipoprotein (HDL) cholesterol is often called “good” cholesterol because it helps transport excess cholesterol from your arteries to your liver, where it can be broken down and removed. When your HDL level is too low, you may be at higher risk for plaque buildup in your blood vessels and, ultimately, heart disease.
According to the American Heart Association and other leading health organizations:
If your HDL level falls below these thresholds, it’s time to look at lifestyle and, in some cases, medical steps to raise it.
Several factors can contribute to low HDL levels:
Most people with low HDL don’t feel any symptoms. Cholesterol problems are usually discovered during a routine blood test called a lipid panel. If you’re unsure about your risk, you could try a free, online symptom check, using the doctor approved Ubie Symptom Checker.
Get moving
Choose healthier fats
Limit refined carbs and added sugars
Maintain or achieve a healthy weight
Quit smoking
Drink alcohol in moderation (if you drink at all)
If lifestyle changes alone aren’t enough, your doctor may discuss medications:
Your doctor will weigh the potential benefits against side effects and interactions with other medications.
While low HDL itself rarely causes immediate symptoms, don’t ignore warning signs of heart trouble:
If you experience any of these, call emergency services or go to the nearest emergency department. For non-urgent questions, speak to a doctor about your cholesterol numbers and overall heart health.
Remember, raising your HDL is a journey. Small, consistent steps—like taking a daily walk or swapping out refined carbs for whole grains—add up over time. Always keep an open dialogue with your healthcare provider, and never hesitate to speak to a doctor about any health concerns, especially if you suspect a heart condition or any other serious issue.
(References)
* Garg A, Simha V. Update on dyslipidemia. J Clin Endocrinol Metab. 2007 May;92(5):1581-9. doi: 10.1210/jc.2007-0275. PMID: 17483372.
* Kelly DM, Jones TH. Testosterone: a metabolic hormone in health and disease. J Endocrinol. 2013 Jun;217(3):R25-45. doi: 10.1530/JOE-12-0455. Epub 2013 Apr 29. PMID: 23378050.
* Hellerstein M, Turner S. Reverse cholesterol transport fluxes. Curr Opin Lipidol. 2014 Feb;25(1):40-7. doi: 10.1097/MOL.0000000000000050. PMID: 24362356.
* Castle J, Feinstein SB. Ultrasound-directed, site-specific gene delivery. Methods Mol Biol. 2014;1141:67-76. doi: 10.1007/978-1-4939-0363-4_3. PMID: 24567131.
* Ossoli A, Neufeld EB, Thacker SG, Vaisman B, Pryor M, Freeman LA, Brantner CA, Baranova I, Francone NO, Demosky SJ Jr, Vitali C, Locatelli M, Abbate M, Zoja C, Franceschini G, Calabresi L, Remaley AT. Lipoprotein X Causes Renal Disease in LCAT Deficiency. PLoS One. 2016;11(2):e0150083. doi: 10.1371/journal.pone.0150083. Epub 2016 Feb 26. PMID: 26919698; PMCID: PMC4769176.
* Zemsky CJ, Sherman SW, Schubert HD, Suh LH. Case Report: Management of Corneal Clouding from Lecithin: Cholesterol Acyltransferase Deficiency. Optom Vis Sci. 2019 Feb;96(2):137-141. doi: 10.1097/OPX.0000000000001329. PMID: 30601362.
* Freeman LA, Karathanasis SK, Remaley AT. Novel lecithin: cholesterol acyltransferase-based therapeutic approaches. Curr Opin Lipidol. 2020 Apr;31(2):71-79. doi: 10.1097/MOL.0000000000000673. PMID: 32073411; PMCID: PMC8525913.
* Masana L, Correig E, Ibarretxe D, Anoro E, Arroyo JA, Jericó C, Guerrero C, Miret M, Näf S, Pardo A, Perea V, Pérez-Bernalte R, Plana N, Ramírez-Montesinos R, Royuela M, Soler C, Urquizu-Padilla M, Zamora A, Pedro-Botet J, STACOV-XULA research group. Low HDL and high triglycerides predict COVID-19 severity. Sci Rep. 2021 Mar 30;11(1):7217. doi: 10.1038/s41598-021-86747-5. Epub 2021 Mar 30. PMID: 33785815; PMCID: PMC8010012.
* Thomas MS, Calle M, Fernandez ML. Healthy plant-based diets improve dyslipidemias, insulin resistance, and inflammation in metabolic syndrome. A narrative review. Adv Nutr. 2023 Jan;14(1):44-54. doi: 10.1016/j.advnut.2022.10.002. Epub 2022 Dec 17. PMID: 36811593; PMCID: PMC10103000.
* Fabian D, Padda IS, Johal GS. Hypoalphalipoproteinemia. 2023 Jan. PMID: 36943964.
We would love to help them too.
For First Time Users
We provide a database of explanations from real doctors on a range of medical topics. Get started by exploring our library of questions and topics you want to learn more about.
Was this page helpful?
Purpose and positioning of servicesUbie Doctor's Note is a service for informational purposes. The provision of information by physicians, medical professionals, etc. is not a medical treatment. If medical treatment is required, please consult your doctor or medical institution. We strive to provide reliable and accurate information, but we do not guarantee the completeness of the content. If you find any errors in the information, please contact us.