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Published on: 2/24/2026
Low HDL cholesterol raises your risk of heart disease and stroke; low means under 40 mg/dL in men and under 50 mg/dL in women, and it usually has no symptoms so it is found on a blood test.
Next steps center on reducing overall cardiovascular risk with regular exercise, quitting smoking, a Mediterranean style diet, weight loss if needed, and controlling blood sugar and triglycerides, plus talking with your clinician about your 10 year risk and whether statins are indicated even if LDL looks okay. There are several factors to consider; see below for causes, how to prioritize changes, specific targets, and urgent warning signs.
If you've been told your HDL cholesterol is low, you might be wondering what that really means for your health. Cholesterol can be confusing, especially when some types are considered "good" and others "bad."
The short answer: Low HDL cholesterol increases your risk of heart disease and stroke. But the good news is that there are clear, evidence-based steps you can take to improve your numbers and protect your heart.
Let's break it down in simple terms.
HDL stands for high-density lipoprotein. It's often called the "good" cholesterol because it helps remove excess cholesterol from your bloodstream.
Think of HDL cholesterol as a cleanup crew. It:
When HDL levels are healthy, this process lowers the buildup of plaque in your arteries. When HDL cholesterol is low, more cholesterol can stay in the bloodstream, increasing the risk of clogged arteries.
According to major cardiology guidelines:
Low HDL cholesterol is one component of dyslipidemia, a condition where blood lipid levels are abnormal.
If you're concerned about your cholesterol levels and want to understand your overall risk better, you can use a free AI-powered Dyslipidemia symptom checker to get personalized insights in just a few minutes.
Heart disease usually develops over many years. It starts with plaque buildup inside arteries — a process called atherosclerosis.
When HDL cholesterol is low:
This increases your risk of:
Low HDL cholesterol often occurs alongside other risk factors, including:
The combination of these factors significantly raises cardiovascular risk.
Several factors can lower HDL cholesterol. Some are genetic, but many are related to lifestyle.
Genetics also play a role. Some people naturally have lower HDL cholesterol levels despite healthy habits.
Here's the important part:
Low HDL cholesterol usually causes no symptoms.
You will not "feel" low HDL. Most people only discover it through routine blood work.
That's why regular cholesterol screening is critical — especially if you:
Yes — but the approach may not be what you expect.
In the past, doctors focused on raising HDL cholesterol numbers directly. However, research has shown that simply increasing HDL with medication does not always reduce heart attack risk.
Today, the focus is on overall cardiovascular risk reduction, not just boosting HDL levels alone.
That said, certain lifestyle changes can improve HDL cholesterol naturally and reduce heart disease risk overall.
Physical activity is one of the most effective ways to raise HDL cholesterol.
Aim for:
Even modest weight loss combined with exercise can improve HDL levels.
If you smoke, quitting can significantly increase HDL cholesterol — sometimes within weeks.
Smoking directly lowers HDL and damages blood vessels. Stopping is one of the most powerful heart-protective steps you can take.
Focus on heart-healthy eating patterns:
Emphasize:
Reduce:
Diets such as the Mediterranean diet are strongly associated with improved cardiovascular outcomes.
Excess abdominal fat is closely linked to low HDL cholesterol.
Even losing 5–10% of body weight can improve lipid levels and insulin sensitivity.
If you have diabetes or high triglycerides, managing these conditions can indirectly improve HDL cholesterol and lower heart risk.
Medication decisions are not based on HDL cholesterol alone.
Your doctor will look at:
In many cases, statins are prescribed if overall heart risk is elevated — even if HDL cholesterol is low but LDL is normal.
Importantly:
You should speak to a doctor if:
These symptoms could indicate a serious cardiovascular issue and require urgent evaluation.
Even if you feel fine, low HDL cholesterol is worth discussing. A healthcare professional can calculate your overall risk and create a prevention plan tailored to you.
It's important not to panic over a single lab result. Low HDL cholesterol is one piece of a much larger puzzle.
Heart disease risk is influenced by:
Improving just one area can positively affect many others.
If you're wondering whether your symptoms or cholesterol levels could indicate dyslipidemia, take a moment to complete this free Dyslipidemia symptom checker — it takes just a few minutes and can help you better understand your risk.
Most importantly, speak to a doctor about any abnormal cholesterol result or symptoms that could signal heart disease. Cardiovascular conditions can be life-threatening, but with early detection and the right steps, they are often preventable and manageable.
Taking action now — calmly and informed — is one of the most powerful things you can do for your long-term health.
(References)
* Rader DJ, Tall AR. HDL cholesterol and cardiovascular disease: Still an enigma? J Clin Endocrinol Metab. 2017 Aug 1;102(8):3191-3199. doi: 10.1210/jc.2017-00215. PMID: 28609756.
* Barter PJ, Kontush A. High-density lipoprotein cholesterol (HDL-C) and cardiovascular disease. Curr Opin Cardiol. 2019 Sep;34(5):543-548. doi: 10.1097/HCO.0000000000000641. PMID: 31335805.
* Kontush A, Kassis N. HDL Cholesterol and Cardiovascular Risk: Beyond the Numbers. Cardiol Rev. 2018 Sep/Oct;26(5):207-212. doi: 10.1097/CRD.0000000000000210. PMID: 30048386.
* Lusis AJ, Fogelman AM, Reue K. HDL cholesterol: role in cardiovascular disease and potential therapeutic strategies. Nat Rev Cardiol. 2020 Jul;17(7):447-458. doi: 10.1038/s41569-020-0355-0. PMID: 32322046.
* Rosenson RS, Badimon JJ, Fuster V. High-density lipoprotein cholesterol (HDL-C) levels and cardiovascular events: Still a strong association? J Clin Lipidol. 2021 May-Jun;15(3):363-366. doi: 10.1016/j.jacl.2021.03.003. PMID: 33867375.
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